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Biomedical subjects

W J van der Gulden

Publications and source records attributed to W J van der Gulden.

15 recordsLinked to original sources

[Animal experiments--no vivisection].

Summary of the inaugural address, delivered on September 21, 1988, on the assumption of the special laboratory animal science chair which was created by the Animal and Society Foundation in the University of Nijmegen. The ethical and scientific conditions to prevent that animal experiments have to be disqualified as 'vivisection' are discussed.

Animal Welfare↗

[Animal models (author's transl)].

Animal models are frequently used in medico-biological studies. The why and wherefore of animal models, the question of the requirements which have to be satisfied by an animal model, the pros and cons of animal models, the question of alternatives, the types of animal models available, the choice that has to be made and the manner in which an animal model is used, are discussed in succession. In addition, the animal models and techniques in use in the Central Animal Laboratory of the University of Nijmegen are reviewed.

Animals↗

[Experiments in animals (author's transl)].

Experiments in laboratory animals are designed to safeguard patients and subjects from possible injury which might be caused by an experiment. It is also expected, however, that results will be more rapidly obtainable, more accurate and more reliable in laboratory animals. Since the beginning of the twentieth century, small animals in particular have been adapted for research by standardization of the genetic pattern, the microflora, the feed and the environment. This was primarily done for the benefit of particular forms of research; subsequently, the need of adapted experimental animals for all research in behalf of medicine, biology, public health and veterinary medicine was recognized. A number of future developments in the field of experimental studies in animals are the following: standardization of large animals such as monkeys, increasing attention devoted to the choice of the animal model and to controlling the conditions in which an experiment is carried out and the coming into operation of the Experiments in Animals Act. These developments will require increasing expertness and close co-operation between investigators, laboratory animal scientists and animal technicians.

Animals↗