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Biomedical subjects

W J de Kort

Publications and source records attributed to W J de Kort.

5 recordsLinked to original sources
PubMed2000

Bath psoralen-ultraviolet A therapy in atopic eczema.

AIMS: To evaluate the efficacy of bath psoralen-ultraviolet A (PUVA) therapy in severe cases of atopic dermatitis (AD) in adults using the extended Six Area, Six Sign Atopic Dermatitis (SASSAD) score. METHODS: Thirty-five adult subjects with severe AD underwent bath PUVA therapy for a maximum of 30 sessions ranging from one to three times a week. The only other treatment allowed during the study was topical application of hydrocortisone. RESULTS: There were a total of six drop-outs, three due to aggravation of symptoms. After the maximum 30 sessions the remaining 29 subjects showed 82.1% improvement in the severity of lesions, 75.2% reduction in extension of lesions, 74% improvement in itching and 79% improvement in night-time rest. Patient evaluations gave an overall score of 8.8 on a scale of 0-10.

Adolescent↗
PubMed1992

[Delayed-type allergy for heparin and fractions of low-molecular-weight heparin].

A patient is described with proven delayed type allergy for heparin and a low molecular heparin. A literature survey shows that the dermatological picture varies. Occurrence of erythematous plaques without a superficial dermatitis is possible. Epicutaneous tests are often not sufficient, and intracutaneous or even subcutaneous tests are necessary to demonstrate the allergy.

Eczema↗
PubMed1990

[The treatment of psoriasis in a day care center].

We describe the treatment of 196 patients with psoriasis, in the psoriasis day care centre at Ede. Treatments involve salt water baths followed by radiation of UVB, additional radiation of the scalp and therapy-resistant parts of the skin and anthralin 'short contact therapy'. During the anthralin therapy the hairy scalp is treated with liq. carb. dexerg. 5% in soya oleum. The results were evaluated by means of the psoriasis area and severity index (PASI) and of a questionnaire which was completed by 144 patients. In an average course of 28.4 treatment sessions (range 9-51), the PASI decreased by 84.3%. Evaluation of the PASI included the hairy scalp, the axillae and the inguinal region. The answers to the questionnaire indicated a risk of rather rapid relapse however, according to many patients, only a small part of the skin surface was affected. The additional value of the treatment is attributed to the setting of the psoriasis day care centre and the relatively safe therapeutic possibilities offered there.

Adolescent↗