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Biomedical subjects

W J Yang

Publications and source records attributed to W J Yang.

At least 55 records · Page 3Linked to original sources

Whole body heat balance during the human thoracic hyperthermia.

A whole-body heat balance model during hyperthermia is developed. In the model, local temperature is calculated using a finite-element model. The perfusion blood, along with its energy, is circulated to the rest of the body, where the heat dissipation is calculated using lumped segments. With this model the effects of the electromagnetic power dosage on the body core temperature and the responses of other body elements are analysed for the human thoracic hyperthermia.

Biophysics↗

[Effect of albendazole and pyrantel in treating intestinal helminthiasis and controlling the recurrence of hookworm infections].

A total of 720 human intestinal helminthic infections were divided into 4 groups and treated with albendazole 400mg/d x 3d, 400mg/d x 5d, pyrantel 1,500mg/d x 3d, or 1,500mg/d x 5d. Half a month after treatment, the negative rates of hookworm egg were 98.6, 98.6, 86.2 and 93.5%, those of ascaris egg were 96.5, 98.2, 92.9 and 96.3%, and those of whipworm egg were 86.4, 89.0, 68.9 and 67.0% respectively. Reduction rate of hookworm egg reached more than 98% in all the 4 groups. Six months after treatment, however, the positive rates of all the 4 groups rose again in varying degrees. The predominant species of hookworm infections was Necator americanus before the treatment and Ancylostoma duodenale after the treatment. It was demonstrated that the recurrence of hookworm infection resulted from A. duodenale infections, while a single dose of 400mg albendazole per day for 3 or 5 days showed good effect in controlling the recurrence of hookworm infections in a certain area.

Adolescent↗

Turbulent flows through a disk-type prosthetic heart valve.

A numerical model is developed to predict the complex velocity, shear and pressure fields in steady turbulent flow through a disk-type prosthetic heart valve in a constant diameter chamber. The governing Navier-Stokes equations are reduced to a set of simultaneous algebraic finite-difference equations which are solved by a fast-converging line-iterations technique. A two-parameter, two-equation model is employed to determine the turbulent viscosity. Numerical results are obtained for stream function, vorticity, and shear and normal stresses. The regions of very high shear and normal stresses in the fluid and at the walls are identified. The maximum value of the shear stress occurring near the upstream corner of the disk may cause hemolysis. The technique can be used together with in-vitro physical experiments to evaluate existing or future prosthetic heart valve designs.

Arteriosclerosis↗

Mass transfer from gas bubbles to impinging flow of biological fluids with chemical reaction.

The rates of mass transfer from a gas bubble to an impinging flow of a biological fluid such as whole blood and plasma are investigated analytically and experimentally. Gases commonly found dissolved in body fluids are included. Consideration is given to the effects of the chemical reaction between the dissolved gas and the liquid on the rate of mass transfer. Through the application of boundary layer theory the over-all transfer is found to be Sh/(Re)(1/2) = 0.845 Sc(1/3) in the absence of chemical reaction, and Sh/(Re) (1/2) = F' (0) in the presence of chemical reaction, where Sh, Re, and Sc are the Sherwood, Reynolds, and Schmidt numbers, respectively, and F' (0) is a function of Sc and the dimensionless reaction rate constant. Analytical results are also obtained for the bubble lifetime and the bubble radius-time history. These results, which are not incompatible with experimental results, can be applied to predict the dissolution of the entrapped gas emboli in the circulatory system of the human body.

Biochemistry↗