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Biomedical subjects

W J Montgomery

Publications and source records attributed to W J Montgomery.

23 records · Page 2Linked to original sources

Arthrotomography of the glenoid labrum.

Arthrotomography was used to study the glenoid labrum in 8 patients with problems of shoulder instability. In 4 patients, an anterior lesion of the labrum was noted radiographically. The abnormality was confirmed at surgery in 3 of the 4. In 1 of the 3, anterior capsular detachment was also demonstrated radiographically and confirmed surgically. One patient had voluntary posterior subluxation: radiographically, the labrum was normal, and at surgery no abnormalities could be found. The technique, which is simple to perform is described and radiographic anatomy discussed.

Adolescent↗

Evaluation of an ultrasmall superparamagnetic iron oxide in MRI in a bone tumor model in rabbits.

Ultrasmall superparamagnetic iron oxides (USPIOs) are a class of MRI contrast agents having moderately selective affinity for the reticuloendothelial cells of lymph nodes and bone marrow. This study evaluated a USPIO preparation, Combidex (Code 7227), in MRI of a rabbit bone tumor model. VX2 carcinoma implanted into the tibial marrow of nine subject rabbits was studied. After tumor growth, the subjects underwent MRI of their lesions both before and after intravenous administration of Code 7227. Code 7227 was judged subjectively to conspicuously reduce the signal intensity of normal marrow on some pulse sequences. A hypointense zone outlined the tumor margins on postcontrast imaging, which allowed improved visualization of the soft tissue component of the larger lesions. Accumulation of the contrast agent in a zone of inflammation outside the tumor margin was demonstrated on histologic sections of the lesions. Code 7227 deserves additional study as a potential contrast agent for MRI of bone tumors.

Animals↗

MR imaging of unusual chordomas.

Chordomas are uncommon primary skeletal neoplasms arising from notochordal remnants. Approximately 50% arise in the sacrum, 35% in the clivus, and less than 15% in the true vertebrae. We report magnetic resonance (MR) studies of four unusual primary chordomas, three in the lumbar region (L1, L2, and L3) and one in the Meckel cave. It is often difficult to differentiate the MR findings of these four tumors from other common neoplasms.

Chordoma↗