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Biomedical subjects

W J Jones

Publications and source records attributed to W J Jones.

At least 55 records · Page 3Linked to original sources

Strategic capital planning scenarios for the future.

Hospitals have traditionally looked to income from operations, depreciation, debt, and philanthropy as their major source of revenue. This viewpoint, however, is changing as hospitals move from being the hub of the healthcare provider network to being spokes in an integrated delivery network (IDN), and the traditional tools of debt financing and revenue optimizing become less effective.

Capital Financing↗

Administrative complement and managerial efficiency in South Carolina hospitals.

This article examines the infrastructure and efficiency of administrative personnel employed by hospitals in South Carolina. The analysis suggests that variation in the administrative complement and the efficiency of hospital administrators is related to the scale of operations and related organizational complexity, the occupancy rate, ownership, and affiliation with multihospital systems. The results of the study also indicate that the administrative complement should be regarded as a resource that results in a discretionary rather than a committed cost and might be altered to increase productivity and improve profitability.

Bed Occupancy↗

Preventing falls in hospitals. The roles of patient age and diagnostic status in predicting falls.

Patient falls are some of the most frequent accidents in hospitals, and they can lead to significant personal and financial costs for both patients and facilities. This study examines the relationship between two patients characteristics and patient falls at a large general hospital and a small psychiatric facility in Tennessee; its findings should be useful for hospital risk management.

Accidental Falls↗

Relationship of alcohol production to lipid composition of yeast in a continuous flow bioreactor.

Saccharomyces cerevisiae was cultivated in a controlled aerated, dual-stage (column), continuous flow bioreactor in a hybrid free-cell and immobilized-cell state. The yeast cells maintained an ethanol concentration of 58-64 and 91-98 g/L in stages I and II, respectively. The lipid composition of the cells cultivated under these conditions was correlated to the effects of aeration by interrupting the aeration on days 113 and 266 of continuous operation. Under conditions of aeration or nonaeration, an alternating increase and decrease in the contents of squalene, sterols, and fatty acids of the respiratory-competent and -deficient unattached free cells was observed. The cellular free lipid compositions of the immobilized cells in the aerated and nonaerated conditions were similar and characteristic of respiratory-deficient cells with the exception of the immobilized cells exposed to a higher ethanol concentration (stage II). These cells contained a broader range of sterol components and increased levels of unsaturated fatty acids than immobilized cells at a lower ethanol concentration (stage I). The neutral lipid to phospholipid ratio decreased for respiratory-deficient cells with phosphatidylethanolamine and phosphatidylinositol being the principal phospholipids. The data demonstrated the essentiality of the hybrid bioreactor design for continuous long term performance and the importance of maintaining specific yeast lipid constituents for continuous high alcohol productivity.

Chromatography, Thin Layer↗

Reality-based strategies for real times.

In today's troubled time, tactical strategic planning can carry a health-care organization only so far. And while strategic planning and risk-taking do not generally go hand-in-hand, maybe it's about time that they do, the author contends. Strategists are certain to find the non-traditional strategic planning initiatives posed below to be provocative, if not compelling.

Hospital Administration↗

Letting technology dictate design.

Hospitals have two basic choices when embarking on major expansion or renovation projects: They can either let the design of the new structure dictate how the hospital will use the technology it houses or let the technology guide design strategy. This article makes a case for the second option--letting technology dictate design.

Diffusion of Innovation↗

Assessment and support of sexual functioning in 458 men seeking genitourinary reconstructive surgery.

Horton and associates focused on an aspect of genital reconstructive surgery: restored or improved sexual functioning. The availability a physician skilled in the application of modern sexual counseling has been demonstrated in a group of 458 men to assist in maximizing the benefit of such surgery on patients' sexual and coital success. The sexual therapist was a valued member of the team approach to patient care. The necessity of psychiatric assessment for some was apparent, as it would be in any population of patients seeking plastic or corrective surgery. The association of the sexual therapist with various mental health professionals was important. The recognition of mental and emotional difficulties was primary, but the further skills the sexual therapist brought by application of sexual therapy techniques was also important. Men disadvantaged sexually by genital abnormality gained from a sensitive and educational approach, one that included their partners in the context of open communication and offered specific suggestions for their own specific needs and situations. Sexual therapy techniques and skills instruction added a vital dimension to the complete care of these men seeking correction of genital abnormalities. The techniques and approaches themselves were fairly straightforward and simple, as well as fairly standardized. Described by Masters and Johnson, Jones and others, they were clearly effective in enhancing comfort with sexuality and less pressured approaches to sexual behavior, and ultimately in enhancing sexual functioning itself.

Gender Identity↗

Role of aldosterone and dietary potassium in potassium adaptation in the distal colon of the rat.

The present experiments were designed to differentiate the effects of aldosterone and chronic potassium loading in the mechanism of colonic potassium adaptation, using a recently described animal model that permits systematic manipulation of aldosterone and dietary potassium. Unidirectional 42K fluxes were performed under short-circuit conditions across isolated distal colonic mucosa from rats with intact adrenal glands and in adrenalectomized, hormone-replaced animals. Administration of a potassium-enriched diet reversed net potassium absorption (+0.43 +/- 0.10 muEq/h.cm2) in intact animals to net potassium secretion (-0.76 +/- 0.08 muEq/h.cm2). Infusion of aldosterone in adrenalectomized animals, in an amount equivalent to that produced by potassium loading in intact rats, reduced JnetK to zero (-0.03 +/- 0.06 muEq/h.cm2). Similarly, zero net potassium transport (-0.14 +/- 0.08 muEq/h.cm2) was observed when experimental rats were fed a potassium-enriched diet and maintained with basal aldosterone levels. Therefore, both elevated aldosterone levels and a potassium-enriched diet had an effect on net potassium transport, but neither produced the full effects of chronic potassium loading. An increase in net potassium secretion (-0.57 +/- 0.07 myEq/h.cm2) comparable to that of intact potassium-loaded animals did, however, occur when potassium loading and elevated aldosterone levels were combined in experimental animals. These studies demonstrate that (a) chronic potassium loading alters active potassium transport by an aldosterone-independent mechanism and (b) the mechanism of chronic potassium adaptation represents the additive effects of increased dietary potassium and aldosterone.

Adaptation, Physiological↗

Evidence of a common pathway of carbon dioxide reduction to methane in methanogens.

The roles of methanofuran and tetrahydromethanopterin as carriers of C1 moieties in the reduction of carbon dioxide to methane were studied in representatives of diverse groups of methanogens, confirming that these roles, first reported for Methanobacterium thermoautotrophicum, are common for methanogenesis in general. Extracts of the methanogens tested converted formyl-methanofuran and methyl-tetrahydromethanopterin to methane; the extractable cofactors derived from the same methanogens, with one exception, complemented a methanofuran- and tetrahydromethanopterin-deficient enzyme system from M. thermoautotrophicum. The amounts of extractable methanofuran and tetrahydromethanopterin were determined for each representative methanogen.

Archaea↗