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Biomedical subjects

W J Fleming

Publications and source records attributed to W J Fleming.

31 records · Page 2Linked to original sources
PubMed1978

Rabies and cerebrospinal nematodosis in woodchucks (Marmota monax) from New York.

Abnormal behavior, suggestive of rabies, is not an unusual finding in woodchucks (Marmota monax). Necropsy records, rabies antibody tests, and necropsy examinations performed by the authors indicate that migration of ascarid larvae usually is responsible for the abnormal behavior, and that rabies is an infrequent finding. Baermannization of brain tissue is suggested for a differential diagnosis.

Animals↗
PubMed1977

Selenium and white muscle disease in woodchucks.

Gross and histologic examination of wood chcks (Marmota monax) trapped on farms in Central New York revealed white muscle disease(WMD). The concentration of selenium in the animal tissues, vegetation and soils in the vicinity of trapping did not consistently correlate with the presence of WMD.

Animals↗
PubMed1976

Effect on caries of self-application of a zirconium silicate paste containing 9% stannous fluoride.

A 2-year clinical trial was conducted using an adolescent population from a low-fluoride area to evaluate the anticaries effect of self-applications of zirconium silicate paste containing 9% stannous fluoride. tthree study groups totaling 464 children, with an initial average of 12.8 years, completed the study. The control group brushed with a non-fluoride zirconium silicate paste (tzircate Prophylaxis Paste) once each year: the first experimental group brushed with zirconium silicate paste containing 9% stannous fluoride (Zircate Treatment Paste) once each year; and the second experimental group brushed every 6 months with Zircate Treatment Paste. After 2 year, the DMFT and DMFS increments were virtually identical for the control group and the group that received one application of fluoride paste per year. The group that received two applications of fluoride paste per year had a DMTF increment that was about 24% less than that of the control group; however, the DMFS increment was only 5% less. These differences were not statistically significant at the P=.05 level.

Adolescent↗
PubMed1976

Preliminary investigation of the life history of Filaroides hirthi Georgi and Anderson, 1975.

Filaroides hirthi lungworm infection increased as a function of age among 47, 9 to 32 week old Beagle pups at a commercial breeding establishment. Probit analysis of these data yielded an estimate of 50% infection was by age 17.4 +/- 3.7 weeks. This parasite and/or its associated lesions remained in at least 40% of infected Beagles at least 10 months after exposure to infection had ceased. Reinfection rendered improbable by the nature of the new environment, a laboratory animal colony. Repeated efforts have failed to demonstrate by the Baermann technique eggs or larvae of this parasite in the feces, bronchial mucus, or intact lung tissue of infected Beagles. All efforts to identify an intermediate or alternate definitive hosts have likewise proved unavailing. Piperazines, dichlorvos, thiabendazole, dithiazanine iodide, and levamisole appear to be without effect on the proportion of Beagles infected. The diet, which contained uncooked meat, was fed in a controlled experiment to 10 Beagles from an uninfected source without producing a single case of F. hirthi infection. Life cycles of other members of the superfamily Metastrongyloidea and possible explanations for the non-patency of F. hirthi infection are discussed.

Age Factors↗
PubMed1881

Pulse Dicrotism.

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Journal Article↗
PubMedDate not supplied

Recovery of cholinesterase activity in mallard ducklings administered organophosphorus pesticides.

Oral doses of the organophosphorus pesticides acephate, dicrotophos, fensulfothion, fonofos, malathion, and parathion were administered to mallard ducklings (Anas platyrhynchos), and brain and plasma cholinesterase (ChE) activities were determined for up to 17 d after dosing. In vivo recovery of brain ChE activity to within 2 standard deviations of the mean activity of undosed birds occurred within 8 d, after being depressed an average of 25-58% at 24 h after dosing. In vivo recovery of plasma ChE appeared as fast as or faster than that of brain, but the pattern of recovery was more erratic and therefore statistical comparison with brain ChE recovery was not attempted. In vitro tests indicated that the potential for dephosphorylation to contribute to in vivo recovery of inhibited brain ChE differed among chemical treatments. Some ducklings died as a result of organophosphate dosing. In an experiment in which ducklings within each treatment group received the same dose (mg/kg), the brain ChE activity in birds that died was less than that in birds that survived. Brain ChE activities in ducklings that died were significantly different among pesticide treatments: fensulfothion greater than parathion greater than acephate greater than malathion (p less than or equal to 0.05).

Animals↗