Search PubMed⌕ Search

Biomedical subjects

W J Fessel

Publications and source records attributed to W J Fessel.

11 recordsLinked to original sources
PubMed1979

Systemic lupus erythematosus as seen in primary care.

Systemic lupus erythematosus does not wholly deserve its bad reputation. At the Kaiser-Permanente Medical Center in San Francisco, the ten-year survival rate among patients with the disease has been about 90%. Many clinicians no longer hold renal biopsy to be mandatory in cases of the disease, even if there is clinical evidence of renal involvement. Clinically significant renal involvement occurs in fewer than 10% of patients. Initiation of corticosteroid therapy when deterioration of renal function is demonstrable is recommended. Cytotoxic agents are seldom indicated.

Adolescent↗
PubMed1978

ANA-negative systemic lupus erythematosus.

The presence of antinuclear antibodies (ANA) in serum is generally considered a decisive diagnostic sign of systemic lupus erythematosus (SLE). Ten patients with clinical signs of disease but persistent negative tests for ANA are examined in this study. Hair fall, Raynaud's phenomenon and recurrent oral ulcers were common in the ANA-negative group. ANA-negative SLE seems to be a subgroup of SLE that has not previously been given adequate attention.

Adult↗