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Biomedical subjects

W J Cumming

Publications and source records attributed to W J Cumming.

At least 37 records · Page 2Linked to original sources
PubMed1987

Review of coracoclavicular ligament reconstruction using Dacron graft material.

Operative management of Grade III acromioclavicular dislocations in young, active patients is a controversial issue with regard to operative management. Nine patients with complete dislocation (Allman Grade III) of the acromioclavicular joint who had undergone reconstruction of the coracoclavicular ligament with woven Dacron arterial grafts were reviewed clinically, radiologically and functionally utilizing an isokinetic dynamometer. Average follow-up was 2 years and 7 months. All results were good or excellent in terms of function, range of movement and patient acceptance. One patient developed a transient brachial plexus lesion due to compression caused by exuberant heterotopic calcification in the region of the synthetic ligament. One other exceptional patient continued to get more than occasional discomfort. It is concluded that Dacron loop repair is a relatively simple surgical technique with minimal morbidity and high efficacy in restoring stability and function in high demand patients.

Acromioclavicular Joint↗
PubMed1987

Subacute myelopathy caused by spinal venous infarction.

A 44 year old female presented with a subacute myelopathy in association with pelvic venous thrombosis. It is inferred from the temporal relationship of these events that the patient suffered a subacute spinal venous infarction. This is discussed along with the aetiology, anatomical distribution and management of the condition.

Adult↗
PubMed1984

Needle biopsies.

Explore the source record for details and available documents.

Biopsy, Needle↗
PubMed1984

Lipid myopathy. Case report and review.

The past decade has seen an increasing number of reports of patients suffering from disorders of lipid with major abnormalities of the neuromuscular system. On the basis of these reports it has been suggested that carnitine deficiency can be subdivided into a myopathic form where the deficiency is confined to muscle and a systemic form where there is more wide-spread carnitine depletion. Recent evidence based on clinical and experimental material casts doubt on this rigid subdivision. It is suggested that patients with carnitine deficiency should not be rigorously subdivided until further clarification of the underlying biochemical abnormalities have been undertaken.

Adult↗
PubMed1982

Computed tomography in dystrophia myotonica.

The calves and thighs of ten patients with dystrophia myotonica and four normal controls were studied by CT. The morphology of the anterior and posterior muscle groups of the calf and the extensor, flexor and adductor groups of the thigh were studied and their attenuation values analysed. Clinical measurement of muscle force was compared with attenuation values in each muscle group. The principal morphological change observed in diseased muscle was fatty infiltration. The amount of fatty infiltration in the calf muscles paralleled the severity of clinically apparent disease. However, in the thigh, fatty infiltration was observed in the extensors of three of the five patients who clinically had involvement of calf muscles alone. Detailed analysis of attenuation values was no better in detecting diseased muscle except of the adductor group of the thigh in those patients with both proximal and distal lower limb involvement. Comparison between muscle force and attenuation values showed a significant correlation in only the anterior muscle group of the calf in the normal controls and in those patients with clinically apparent disease of the calf muscles alone.

Adult↗
PubMed1982

Femoral shaft fractures in children: the effect of initial shortening on subsequent limb overgrowth.

Twenty-six children between the ages of ten months and 15 years with closed fractures of the femoral shaft treated by closed means were reviewed to determine whether shortening at the time of fracture union overcame the problem of subsequent limb overgrowth. The mean shortening at the time of union was 9.8 millimeters. The mean overgrowth was 8.8 mm. The initial shortening and subsequent limb overgrowth were related, with a correlation coefficient of 0.63 (p less than 0.01). The greater the initial shortening, the stronger appeared to be the stimulus for overgrowth.

Adolescent↗
PubMed1981

Morphometric comparison of Duchenne's muscular dystrophy and experimental bupivacaine myopathy.

The findings of this study confirm the role of the hyaline fibre in D.M.D. and support the concept of continuing necrosis with progressive failure of regeneration as the major factor in the aetiology of the pathological changes. The persistence of internal nuclei , "split" fibres and progressive fibrosis are secondary phenomenon. Comparison of the changes in D.M.D. with those seen in experimental Bupivacaine myopathy shows that the changes in the experimental myopathy are comparable to those seen in D.M.D. between the ages of 4 and 6 years. It is suggested that Bupivacaine myopathy is an acceptable animal model for D.M.D.

Animals↗
PubMed1980

Cardiac complications of polymyositis.

We report 3 cases of polymyositis, confirmed by enzyme assay and muscle biopsy, complicated by serious cardiac disease. They showed progressive fascicular block, despite immunosuppressive therapy sufficient to control the skeletal muscle disease, culminating in complete heart block with syncope, requiring the implantation of a pacemaker. In addition, all 3 showed echocardiographic evidence of dilated cardiomyopathy.

Adult↗
PubMed1980

Procainamide-induced myositis.

The risk of developing a syndrome resembling lupus erythematosus when taking procainamide has been well recognized for over 15 years, although the development of myopathy has been reported on one occasion only, in this instance without histopathological evidence of muscle inflammation. The patient reported in this paper developed a severe, rapidly progressive vasculitis, apparently limited to muscle, after taking procainamide for 42 months, his myopathy remitting rapidly after withdrawal of the drug and a short course of treatment with azathioprine. Although this man had no clinical evidence of SLE, he had impressive immunological evidence to support this diagnosis.

Aged↗
PubMed1980

Hydrocephalus and tuberculous meningitis in adults.

Hydrocephalus is well recognised as a complication of tuberculous meningitis in childhood. This complication may occur more frequently in the acute stage in adults than has been appreciated. Three cases are described to illustrate this observation. Early recognition and prompt treatment may improve mortality and morbidity at any age.

Adolescent↗
PubMed1979

Acute intoxication with sodium valproate.

Two epileptic patients developed an acute toxic encephalopathy consisting of altered behavior, deteriorating seizure control, and confusion while taking sodium valproate alone. Serum valproate levels were greater than 100 microgram/ml in both. Toxic symptoms resolved when the dose of valproate was reduced, with a consequent fall in serum concentration of the drug.

Acute Disease↗