Search PubMed⌕ Search

Biomedical subjects

W J Bock

Publications and source records attributed to W J Bock.

At least 91 records · Page 5Linked to original sources
PubMed1978

[Diverse findings in cranial CT and scintigraphy in space occupying lesions (author's transl)].

Incongruent statements in CT and scintigraphy may disturb therapy planning. Many years of scintigraphy have presented here an established method. Cranial CT was performed here with 2000 persons in one year. Parallel CT and scintigraphy was performed in about 350 cases. There were some cases with positive findings in CT and negative in scintigraphy and vice versa. These cases will be compared with the definite diagnosis, we will discuss the different findings and the relevance of both methods as a diagnostic aid for the neurosurgeon and therapeutic radiologist.

Brain Neoplasms↗
PubMed1977

Electroencephalographic investigations of traumatic apallic syndrome in childhood and adolescence.

Reports of electroencephalographic changes in cases of the traumatic apallic syndrome in children and adolescents are very rare. We tried to correlate special electroencephalographic patterns with the three different stages that are usually seen. We found high voltage subdelta and delta activity in the initial symptom complex, an EEG with dominating delta-theta activity and voltage of medium height corresponding to the fully developed stage, and a flat theta EEG in the stage of remission. The difficulties in interpretation of the changes, especially in children, are discussed. Longitudinal electroencephalographic studies are recommended for diagnosing complications, such as haematomas or palsies, and for prognosis.

Accidents, Traffic↗
PubMed1977

[Elektro-clinical results in cases with carotis-sinus-cavernosus-fistula (author's transl)].

Eight cases of carotid cavernous fistulas are reported. Electroencephalograms were done before, during and after operative attack und during digital carotid compression. Preoperative, there was a mild general slowing, ipsilaterally marked in the parieto-temporal region. During digital carotid compression slowing may be found on the opposite side because of a steal syndrome. The degree of these physical changes and of those during hyperventilation depends on the individual cerebral blood flow and the corresponding situation of cerebral blood flow and the corresponding situation of cerebral metabolism. These changes are especially marked under anaesthetics. That is why derivations under anaesthetics seem to be most important for indicating the operation and to be correlated to the functional disturbances by the fistula. delta-activity is no contra-indication, when faster activity is superposed. Seizure potentials, only, seem to be a contra-indication. Pathogenetic mechanisms of electroencephalographic changes are being discussed. From that can be concluded that early operative treatment is necessary. Especially if the patient is young, there may be no need for compression training. Simultaneously, there is a possibility for curing neuro-ophthalmic disturbances.

Adolescent↗
PubMed1976

Analysis of fiber types in the pigeon's metapatagialis muscle. II. Effects of denervation.

The pigeon's metapatagialis muscle consists of three slips, two twitch and one tonic, and these slips are distinguishable at the gross anatomical level. Comparative studies of denervation are facilitated because the two fiber types are under the same mechanical forces, can be denervated as one muscle, and can be distinguished after denervation. Both fiber types atrophied after denervation, with the twitch fibers having a more variable response. Pathological alterations observed by light microscopy suggested that the twitch fibers were more affected by denervation than the tonus fibers. Ultrastructurally, both fiber types showed the same changes, with the twitch fibers again being more consistently altered. Proliferation of the transverse tubular system and sarcoplasmic reticulum were more marked in the tonus than twitch fibers, and the sarcoplasmic reticulum proliferated prior to the transverse tubules. Filament and fibril degeneration, peripheral and central degeneration, lysosomes and their derivatives, and satellite cell proliferation were common to both fiber types. Contracture knots were common to the denervated fibers, and were suggested to be characteristic of degenerating fibers. Degenerating motor end plates were observed, and most neurons in the fibers were naked, lacking myelin sheaths. The results are discussed in relation to the function of the neuron in maintaining the muscle, and the possibility of denervation inducing a transformation of tonic to twitch fibers.

Animals↗
PubMed1976

[Blood gas analytical study on cerebral circulation under the influence of dihydroergotoxin (author's transl)].

The demand for sufficient blood supply and oxygenation of cerebral tissue after brain surgery or severe head injuries requires the clinical investigation of drugs which are supposed to improve cerebral blood flow and metabolism. We have therefore used the hydrogenated derivatives of the ergotoxin components of the secale alcaloids in the post-operative and posttraumatic period of neurosurgical patients, respectively, and studied their effect on cerebral metabolism by successive analysis of blood gases in the arterial and venous blood. A significant increase of cerebral venous CO2-concentration following the administration of dihydroergotoxin in these patients in all probability is attributable to an improved O2-utilisation in the cerebral tissue.

Blood↗
PubMed1975

The relation between intracrainal pressure, mean arterial pressure and cerebral blood flow in patients with severe head injury.

UNLABELLED: In patients with severe head injuries ICP, MAP and CBF were measured continuously. In most patients there was a positive vasopressor response to increasing ICP, but the ICP/MAP ratio varied considerably in individual cases. CBF was diminished either by increasing ICP or by decreasing MAP. This effect was more marked with ICP above 40 mm Hg or MAP below 110 mm Hg. In terminal stages there was often a negative MAP/ICP ratio accompanied by massive cerebral hyperaemia. Key words: Severe head injury--intracranial pressure--mean arterial pressure--cerebral blood flow--cerebral perfusion pressure--critical limit of ICP and CBF. ABBREVIATIONS: ICP equals intracranial pressure (mm Hg); CBF, Flow equals cerebral blood flow (ml/min); MAP equals mean arterial pressure (mm Hg); CPP equals cerebral perfusion pressure (mm Hg) (difference between MAP and ICP); BP equals blood pressure.

Blood Pressure↗
PubMed1975

Demonstration of cervical spinal canal before and after fusion operation.

With the help of myelography using "oil soluble" positive contrast media, it is possible with a horizontal beam and a prone patient to outline the dorsal limit of the vertebrae and to estimate the degree of disc protrusion in the cervical region. In order to demonstrate the effect of anterior "ventral" fusion and especially the removal of the disc protrusion a large number of patients were again subjected to myelography following operation. It was; therefore, desirable that the contrast medium instilled pre-operatively should be mobilized in order to achieve such a demonstration in the cervical region. The method of operative myelography are described and illustrated by photographs.

Cervical Vertebrae↗
PubMed1975

[Long-Term Results of Surgical Treatment of Spinal Tumours in Children and Adolescents].

Catamneses of children up to the age of 16, operated on spinal tumours, are reported. Spinal tumours of this age account for about 15% of the total (all ages). There are about 50% intradural and 50% extradural tumours. The most frequent extradural tumours are sarcomas, followed by lipomas and dysontogenetic tumours like teratomas. Intradural tumours consist of intramedullary and extramedullary ones, about 50% each. Intramedullary tumours are gliomas, extramedullary ones may be neurinomas, meningeomas and vascular tumours. Time from onset of first diffuse symptoms up to clinical diagnosis depends on growth tendency of the tumour as well as on its localization. Hence, case history in cases of intramedullary gliomas usually covers two years, of sarcomas only a couple of months. In half of the cases, pain was the first symptom, followed by disturbed motor function. In more than 50% of the cases, complete restoration or significant improvement could be achieved by surgery. In the remaining half, there was either no change or even deterioration of the disturbed function. It seems justified to replace the former pessimistic attitude towards therapy of spinal tumours in childhood by a discret optimism. If in addition other spinal diseases like disk herniation are taken into account, prognosis is even more favourable.

Adolescent↗