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Biomedical subjects

W J Bean

Publications and source records attributed to W J Bean.

At least 55 records · Page 3Linked to original sources
PubMed1985

Hepatic cysts: treatment with alcohol.

Six patients with hepatic cysts were successfully treated with percutaneous aspiration and temporary direct injection of sterile alcohol U.S.P. (95% ethanol) into the cyst cavities through an aspiration catheter. Five cysts were treated percutaneously using sonographic guidance, and one cyst was treated under direct vision during a cholecystectomy. It is ideal to treat with 25% replacement volume of alcohol. The larger cysts may require more than one alcohol treatment at the same sitting to be effective. There was no recurrence of the treated cysts on follow-up examinations of 6-18 months. Minor complications of transient pain, temperature elevation, and hemorrhage into a cyst occurred. No major complications were encountered. The results of this series would indicate that aspiration and injection of alcohol is the treatment of choice for symptomatic congenital hepatic cysts.

Aged↗
PubMed1985

Fibrous mass complicating epidural morphine infusion.

The benefits of continuous epidural morphine infusion using an implanted pump delivery system to control intractable cancer pain have recently been described. Most articles on this subject relate to dosage, technique, degree of pain relief, and tolerance. There are some anticipated complications of the treatment related to the surgical implantation of the system and drug toxicity. We present a complication presumably related to the epidural catheter. A fibrous reaction that developed around the catheter tip progressed into a mass. This caused a significant displacement of the spinal cord with the development of long tract symptoms. Identification of this abnormality using myelography and computed tomography led to prompt surgical decompression resulting in improvement of the patient's condition.

Aged↗
PubMed1984

Correlation of influenza A virus nucleoprotein genes with host species.

The RNAs coding for the nucleoproteins of a panel of influenza isolates from human and nonhuman hosts were compared by RNA-RNA hybridization to determine the extent of genetic diversity of this protein and to determine if related nucleoproteins (NP) are consistently found in viruses from certain hosts. Five nucleoprotein groups were defined. Group 1 contains nearly all of the avian influenza viruses, group 2 includes only certain viruses isolated from gulls, group 3 includes all recent equine influenza strains, group 4 contains only equine/Prague/1/56, and group 5 contains all human and swine influenza isolates. The maintenance of specific nucleoproteins in viruses from certain species suggests that these proteins have evolved functionally significant differences that favor their replication in a specific host.

Animals↗
PubMed1984

Subclavian steal: treatment with percutaneous transluminal angioplasty.

Three cases of subclavian steal were treated with percutaneous transluminal angioplasty of the subclavian stenosis. One patient had dilatation of the lesion three separate times, without CNS complications. Initial screening with continuous wave Doppler ultrasound proved successful in identifying patients with the subclavian steal phenomenon and any associated carotid disease.

Angioplasty, Balloon↗
PubMed1984

Are seals frequently infected with avian influenza viruses?

Influenza A virus isolates of the H4N5 subtype (which has previously been detected only in birds) were recovered from harbor seals dying of viral pneumonia on the New England coast from June 1982 through March 1983. When these isolates were compared with other mammalian and avian viruses in serological assays and RNA-RNA competitive hybridization, it was found that the seal viruses were most closely related antigenically and genetically to recent avian virus strains and were readily distinguishable from mammalian viruses, including H7N7 isolates recovered from seals in 1980. Unlike any previous isolates from mammals, these recent seal viruses replicate in the intestinal tracts of ducks, a characteristic of avian viruses. The association of avian viruses with influenza outbreaks in seals suggests that transmission of avian viruses to seals is occurring in nature. Potentially, this may be an example of the adaptation of avian viruses to mammals, which would represent an intermediate step in the evolution of new mammalian strains.

Animal Diseases↗
PubMed1983

Swine influenza-like viruses in turkeys: potential source of virus for humans?

Influenza A viruses (subtype H1N1), recently isolated from turkeys in different areas of the United States, were determined to be closely related to strains typically associated with pigs. This conclusion was based on comparisons of H1N1 isolates from pigs, humans, ducks, and turkeys with polyclonal and monoclonal antibodies, RNA-RNA competitive hybridization, and replication studies. One of the H1N1 isolates from turkeys caused influenza in a laboratory technician, who displayed fever, respiratory illness, virus shedding, and seroconversion. These results suggest that turkeys as well as pigs are involved in the maintenance of these viruses and their transmission to humans.

Animals↗
PubMed1983

Mediastinal pancreatic pseudocyst.

We have described a case of extension into the mediastinum by a pancreatic pseudocyst. This rare phenomenon should be included in the differential diagnosis of mediastinal mass lesions. We advocate the use of CT in evaluating a mediastinal mass to determine its solid or cystic nature, size, extent, and relationship to adjacent structures.

Adult↗
PubMed1982

Mass mortality of harbor seals: pneumonia associated with influenza A virus.

More than 400 harbor seals, most of them immature, died along the New England coast between December 1979 and October 1980 of acute pneumonia associated with influenza virus, A/Seal/Mass/1/180 (H7N7). The virus has avian characteristics, replicates principally in mammals, and causes mild respiratory disease in experimentally infected seals. Concurrent infection with a previously undescribed mycoplasma or adverse environmental conditions may have triggered the epizootic. The similarities between this epizootic and other seal mortalities in the past suggest that these events may be linked by common biological and environmental factors.

Animals↗