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Biomedical subjects

W I Anderson

Publications and source records attributed to W I Anderson.

At least 37 records · Page 2Linked to original sources
PubMed1990

Two rare cutaneous neoplasms in horses: apocrine gland adenocarcinoma and carcinosarcoma.

Two rare equine cutaneous neoplasms, an apocrine gland adenocarcinoma and a carcinosarcoma were diagnosed in a 17-year-old pony and a 14-year-old mare, respectively. The apocrine gland adenocarcinoma was present on the prepuce. Histologically, papillary projections of low cuboidal to columnar epithelial cells were generally well differentiated, and surrounded dilated acini. Stromal invasion was present, but vascular and lymphatic invasion was not seen. The carcinosarcoma was present in the right flank of the mare. Two discrete cell populations were characterized histologically. One portion of the mass was composed of elongated, loosely arranged mesenchymatous cells; the second population consisted of dense sheets of pleomorphic, basophilic cells forming irregular acini.

Adenocarcinoma↗
PubMed1990

Infarction of the pons and medulla oblongata caused by arteriolar thrombosis in a horse.

Infarction of the pons and rostral medulla secondary to arteriolar thrombosis was documented histologically in a 17-year-old mixed-Arabian female horse. Clinically, the animal experienced a sudden onset of a head tilt and subsequent non-controllable seizures. There was no historical, clinical or histological evidence to suggest the presence of infection of Equine Herpesvirus-1 or the feeding of corn contaminated by Fusarium moniliforme.

Animals↗
PubMed1989

Multifocal bullous emphysema with concurrent bronchial hypoplasia in two aged Afghan hounds.

Multiple scattered foci of bullous emphysema were detected in the lungs of two aged Afghan Hounds. The affected parenchyma contained bronchi with rudimentary cartilage and small smooth muscle bundles. The bronchi were generally lined by cuboidal epithelium. The animals were generally asymptomatic throughout their entire lives. One, the female, developed dyspnoea and tachypnoea terminally, following the rupture of two bullae.

Animals↗
PubMed1989

Eurytrema procyonis in a raccoon (Procyon lotor) from New York state--a first report.

The digenean, Eurytrema procyonis, found in the pancreatic ducts of the raccoon (Procyon lotor), is reported for the first time from a juvenile female raccoon captured in July 1987, in New York State (USA). The presence of greater than 183 trematodes in the pancreatic ducts was an incidental finding at necropsy to an interstitial pneumonia which had caused emaciation, and for which the animal was euthanized. The pancreas, with the exception of the major pancreatic duct, was histologically normal. The duct, containing the parasites, was dilated and contained a diffuse subepithelial inflammatory infiltrate consisting primarily of eosinophils. Epithelial hyperplasia was present in tubulo-alveolar glands, and goblet cells were prominent.

Animals↗
PubMed1989

Thyroid follicular carcinoma with pulmonary metastases in a beaver (Castor canadensis).

An 11-yr-old female beaver (Castor canadensis) died after a 3 1/2 mo course of intermittent diarrhea, lethargy and anorexia. A postmortem examination revealed both a necrotizing ulcerative colitis and bilaterally enlarged thyroid glands. Histologically, the necrotizing colitis was similar to that caused by canine or feline parvovirus. Thyroid glands were multilobulated. Lobules were composed of irregularly arranged, variably sized follicles, some of which contained colloid. Follicles were lined by a pleomorphic population of tall cuboidal to columnar epithelial cells. Capsular invasion was present. Similar cells, forming follicles were present within the pulmonary parenchyma. This is the first documented case of a thyroid follicular carcinoma with pulmonary metastases in a beaver.

Adenocarcinoma↗
PubMed1989

Study of association between histologic features and echogenicity of architecturally normal cat kidneys.

Thirty-eight grossly and histologically normal cat kidneys were examined ultrasonographically. The echogenicity of the renal cortex was subjectively evaluated by scoring it as largely or not largely different from the echogenicity of the renal medulla and as similar or not similar to the echogenicity of the renal sinus. The presence or absence of a medullary hyperechoic band was determined. The length, width, and height of each kidney was measured. Hematoxylin and eosin-stained sections of each kidney were examined microscopically. The amount of fat vacuoles in the tubular epithelium of the renal cortex was scored as plentiful or not plentiful. The presence or absence of a medullary band of mineral deposits within the lumina of renal tubules was determined. A plentiful amount of fat vacuoles in renal cortex was associated positively with a large difference in echogenicity between cortex and medulla (P less than 0.01) and with similar echogenicity of cortex and sinus (P less than 0.01). The presence of a medullary hyperechoic band was associated positively with a band of mineral deposits within medullary tubular lumen (P 0.01). Kidneys with a large difference in echogenicity between cortex and medulla and kidneys with a plentiful amount of fat vacuoles were not significantly different in size (P = 0.56). These groups were larger (P less than 0.01) in length, width, and height than were kidneys without a large difference in echogenicity between cortex and medulla and kidneys that did not have plentiful cortical fat vacuoles.

Animals↗
PubMed1989

Presumptive subcutaneous surgical transplantation of a urinary bladder transitional cell carcinoma in a dog.

A urinary bladder mass in a 12-year-old spayed female West Highland White Terrier was diagnosed after exploratory surgery and biopsy as a transitional cell carcinoma. Four months later the dog presented with an ulcerated plaque-like cutaneous lesion at the previous surgical incision site; concurrent inguinal lymphadenopathy and recurrence of the urinary bladder mass were identified. Transitional cell carcinoma was diagnosed at all 3 sites. Although a definitive relationship cannot be established between the initial surgery for urinary bladder mass and the resultant subcutaneous lesion, surgical implantation should be considered as a source for the neoplastic cells.

Animals↗
PubMed1989

Subclinical lumbar polyradiculopathy in aged domestic, laboratory, and exotic mammalian species--a light and selected electron microscopic study.

Lumbar polyradiculopathy, characterized by ballooning myelin sheaths and axonal distortion, was documented in multiple, aged, domestic, laboratory, and exotic mammalian species. Animals studied that exhibited this nerve rootlet change included the goat, sheep, pig, white-tailed deer, gerbil, vole, ferret, beaver, hedgehog, chinchilla, North Chinese leopard, lion, cheetah, mountain lion, llama, East African eland, Uganda giraffe, polar bear, and drill. Ultrastructurally, lumbar nerve rootlets from the North Chinese leopard revealed prominent and often multiple lamellar separations in the area of myelin bubbling. Clefts in myelin sheaths contained macrophages with engulfed fragments of myelin. Axons were sometimes variously attenuated, and the axoplasm contained densely packed neurofilaments. In all species, the lesion was subclinical and considered an incidental age-related finding.

Aging↗
PubMed1989

Idiopathic benign lichenoid keratosis on the pinna of the ear in four dogs.

Histologically, multiple wart-like papules or hyperkeratotic plaques on the ear pinnae from 4 dogs were characterized as idiopathic benign lichenoid keratosis. Common histologic features included a discrete lesion of irregular and papillated epidermal hyperplasia with a moderate diffuse lichenoid interface inflammatory infiltrate consisting of lymphocytes and plasma cells. There was also focal hydropic degeneration of the epidermal basal cell layer, pigmentary incontinence, and mixed orthokeratotic and parakeratotic hyperkeratosis. In all 4 dogs, the pinnal lesions were unilateral and asymptomatic. Complete surgical excision was curative.

Animals↗
PubMed1988

Cerebellar infarction caused by arterial thrombosis in a dog.

A cerebellar infarction was found to be caused by a vascular thrombosis in a dog. The cause of the thrombosis was not determined. The dog had signs of a central vestibular disturbance. Scintigraphic imaging of the brain revealed evidence of increased uptake of the radionucleotide within the cranial vault. Analysis of CSF revealed albuminocytologic dissociation. Histologically, there was severe, locally extensive, well-demarcated hemorrhagic necrosis within the left cerebellar hemisphere. A mural thrombus was evident within a large meningeal artery. Although thrombosis of cerebrospinal vessels is rare in the dog, it should be considered in the differential diagnosis as a cause of acute CNS dysfunction.

Animals↗