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Biomedical subjects

W House

Publications and source records attributed to W House.

At least 19 recordsLinked to original sources
PubMed1991

Lymphocyte-macrophage activity in the human endolymphatic sac.

The human endolymphatic sac was analysed electron microscopically in patients undergoing acoustic Schwannoma surgery or vestibular nerve section. In addition, endolymphatic sacs from cadavers were analysed light microscopically. The results show that the human sac is endowed with a variable number of leucocytes and that there is a continuous recirculation of immuno-competent cells in this area of the inner ear that may be of importance for clearance of the inner ear from foreign substances and microorganisms derived from nearby located infection-prone areas. The possibility in Meniere's disease of a disturbed immunological activity in the sac is discussed.

Ear, Inner↗
PubMed1990

Normal nasal airway resistance in noses of different sizes and shapes.

Measurement of nasal airway resistance is becoming a common clinical technique. Accurate definition of the normal range of airflow is critical for maximal usefulness of this technique. Since typical nasal size and shape vary greatly with ethnic background, different norms for different ethnic groups may be appropriate. Nasal airway flow and resistance and external nasal size and shape were measured in 130 asymptomatic subjects (52 black, 56 white, and 22 Hispanic). Nasal length, width, columellar length, and nasolabial angle were similar for whites and Hispanics, but both groups differed significantly from blacks--even when changes attributable to biologic aging were factored out. In spite of these differences, there was no significant difference in any nasal airflow or resistance parameter among groups, suggesting that currently used airflow and resistance standards are valid for these three different ethnic groups.

Airway Resistance↗
PubMed1990

[Cochlear implants].

William House gives in the address the essential of his philosophy about cochlear implant: "My 30 years of experience with cochlear implants has gone by very quickly. It is only during the past 10 years that cochlear implants have been widely used throughout the world. During that 10 years we have seen a change in the attitudes of scepticism and outright feeling of opposition to this technology to general acceptance and widespread interest. Implants are still in their infancy, and my present feeling is that it will take at least 20 years for this technology to reach maturity. I feel that we will only reach the ultimate maturity of cochlear implant technology if we keep a very open mind as to different types of devices and processing schemes, and if we try to keep our technology as simplified as possible in order to minimize our clinical time in working with these patients, and also minimize the cost of the manufacturing and maintenance of complex systems".

Adult↗
PubMed1987

Comparison of outcome of low-risk labour in an isolated general practice maternity unit and a specialist maternity hospital.

The outcome of labour of 185 low-risk pregnancies at an isolated general practitioner maternity unit was compared with that for 185 comparable low-risk pregnancies at a specialist maternity hospital. No difference was found in mode of delivery or in the proportion of women requiring no analgesia, although significantly more women in the general practice group received analgesia beyond nitrous oxide. There was a significantly higher level of intervention in labour in the maternity hospital group in the form of fetal monitoring and augmentation of labour. The duration of first stage of labour was longer and meconium staining less frequent in the general practice group. Fourteen (7.6%) of the general practice group were transferred in labour to the specialist unit.The results suggest that where considerations for selection of low-risk pregnancy permit, the general practice maternity unit can provide a distinctive style of intrapartum care with minimum intervention.

Delivery Rooms↗
PubMed1987

Outcome of women booked into an isolated general practice maternity unit over eight years.

The outcome of pregnancy of 1303 women admitted for delivery (including those transferred after admission) at an isolated general practitioner maternity unit over the period 1978-85 was studied. The outcome following change of booking before admission was also assessed for the years 1982-85. The crude perinatal mortality rate was 1.5 per 1000 for all admissions between 1978 and 1985. Of the women admitted in 1978-85 7.4% were transferred after admission while for those booked at the unit in 1982-85 11.3% had their place of booking changed. A higher proportion of nulliparous women than multiparous women were transferred or had their place of booking changed. The main reasons for transfer after admission were delay in the first stage of labour (21.9%), spontaneous rupture of membranes not in labour (16.7%) and hypertension (15.6%), and for change of booking postmaturity (26.9%) and hypertension (16.4%).Sufficient information concerning risk of transfer and change of booking may now be available from studies of isolated general practice maternity units for pregnant women at low risk to make an informed choice of place for delivery.

Delivery Rooms↗