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Biomedical subjects

W Hoppe

Publications and source records attributed to W Hoppe.

At least 109 records · Page 6Linked to original sources
PubMedDate not supplied

Permanent deafness associated with furosemide administration.

Six cases of hearing impairment have been presented. Furosemide was administered to all of these patients at the time of the alleged onset of the deafness. None of the known or suspected causes of deafness occurring in transplant patients was evident in these cases. With the experimental evidence that furosemide does induce stria damage and the absence of other recognized causes of deafness in this series of patients, furosemide must be considered the etiologic agent responsible for the permanent sensorineural hearing loss. A characteristic audiometric pattern of hearing impairment emerged and a possible explanation for these features has been given. Certain precautionary steps in the use of ototoxic drugs are suggested.

Acute Kidney Injury↗
PubMedDate not supplied

[Ultrastructural findings of the muscles around lip clefts].

Our electron microscopic observations show alterations of the muscles near the cleft margins confirming the theory resulting from light microscopic and immunohistochemical findings that the myogenic structures surrounding cleft margins are inferior tissue that is capable neither of regeneration nor of normal function. The clinical implication derived from these observations is that the tissue in the vicinity of the clefts should be generously excised when doing cheiloplasties.

Cleft Lip↗
PubMedDate not supplied

[Auxiliary MR spectroscopy of blood plasma in the diagnosis of malignant head and neck tumors].

Magnetic resonance (MR) spectroscopy of an EDTA or citrate plasma sample (also referred to as "Fossel test" after Fossel, who first described it) started out as a promising method for fast and simple diagnosis of malignancies. Although the results of our own studies of the head and neck area confirm this tendency, we believe--and so do meanwhile also other investigators--that the clinical use of this test in its present form is not feasible because of lacking specificity.

Adult↗