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Biomedical subjects

W Hollmann

Publications and source records attributed to W Hollmann.

At least 91 records · Page 5Linked to original sources
PubMed1980

[Fifty years of ergospirometry (author's transl)].

With the development of ergospirometry, Knipping and Brauer introduced the diagnosis of performance in 1929. Ergospirometric methods have a certain importance today in research, diagnosis, therapy, rehabilitation, training and sport. Medical special disciplines such as sports medicine, pulmonology, cardiology, occupational medicine, social medicine and physiology of performance and also the fields of biomechanics, clinical pharmacology and biochemistry make use of ergospirometry and owe much new knowledge to it.

Biomechanical Phenomena↗
PubMed1980

[Global and regional changes of cardiopulmonary blood volume under continuous work load (author's transl)].

The present study describes a method for the continuous determination of global and regional stress-induced alterations of cardiopulmonary blood volumes in normals, trained athletes and patients with latent cardiac insufficiency. In contrast to normals and athletes there is an increase of the total cardiac blood volume in the cardiac patients. There are also significant differences in blood volume changes of the left lung between normals and athletes on the one hand and the cardiac patients on the other. The method is simple and non-hazardous; it permits the observation of the obviously different adaptation of the cardiopulmonary system during exercise in normals, athletes and cardiac patients.

Adaptation, Physiological↗
PubMed1979

[Carbohydrate-reduced diet and metabolism: about the influence of a 4-weeks isocaloric fat-rich, carbohydrate-reduced diet on body weight and metabolism (author's transl)].

The influence of a 4-weeks carbohydrate-reduced, fat-rich diet on 9 slightly overweighted men was investigated. Caloric and protein intake remained unchanged. 70% were fat, 20% carbohydrates. Glucose, cholesterol, triglycerids, serumproteins, urea, uric acid, sodium and potassium were measured in rest. At a 60 minutes bicycle ergometer test glucose, triglycerids, free fatty acids and glycerol were registrated before and after 20 and 60 minutes work. The intensity was 70% of the maximal oxygen uptake. These were the most important results: (1) Body weight decreased continuously. One of the causes is an elevated heat production. (2) Serum-protein and -glucose remained unchanged. Cholesterol and triglycerides were reduced. Serum-urea, -sodium and -potassium diminished continually. On the contrary, uric acid raised over the normal range. (3) Work performance was reduced for 20%. (4) Hypoglycemic values did not appear. The oxidation of fat by the working muscles, and fat mobilisation increased by a fat-rich diet.

Adult↗
PubMed1979

[Hip near osteosynthesis, total hip replacement and prevention of thromboembolism (author's transl)].

The effect of physiotherapy and pharmacological treatment in preventing thromboembolic disease at hip-near operations was compared from 1971 to 1978 in 787 patients being more than 60 years old. Physiotherapy alone and its completion by Dextran and Acetyl-salicylic-acid turned out to be insufficient. It was only by low-dose Heparin in combination with Dihydroergotamin (Dihydergot) and continuing physiotherapy that the rate of thromboembolism could be lowered effectively.

Dihydroergotamine↗
PubMed1979

[Possibilities of calculating the fat-free body mass and its reaction to a carbohydrate-poor, fat-rich diet].

9 healthy medical students got an isocaloric fat-rich carbohydrate-reduced diet during 14 days. Body-weight and lean body mass were registrated. We calculated lean body mass from measurement of skinfold thickness, total body potassium and total body water. Body-weight was reduced highly significantly by 3.4 kg on an average. Body potassium and body water remained unchanged. It can be concluded from these results that weight loss was caused by an exclusive reduction of the fat mass.

Adult↗
PubMed1978

Skeletal age and submaximal working capacity in boys.

Skeletal age (SA) and Vo2 at a heart rate of 130 (Vo130) during work on a bicycle ergometer were measured in 237 boys 8-18 years of age. Analysis indicates that Vo130 is well correlated with SA, but also is equally well correlated with chronological age (CA), height and body weight. Age-specific correlations show that Vo130 is associated with SA from 12 through 16 years of age. Partialing out SA results in a significant decrease in the correlations of either height or weight with Vo130 only in the 12-16 year subgroup. The total common variance explained in Vo130 when regressed over CA, height and weight is affected by the presence of SA only in the 12-16 age subset. In spite of the high degree of multicollinearity among the independent variates, correlation data seem to indicate that SA and Vo130 have a slightly higher degree of relationship circumpuberally, i.e. between 12 and 16 years of age.

Adolescent↗
PubMed1977

Modifications of serum glycoproteins the days following a prolonged physical exercise and the influence of physical training.

Eight male subjects (mean age 24.1 +/- 2.6 years) performed at intervals of 2 weeks successively a 3 h and two 2 h runs of different running speed. The days following the running there were moderate elevations of C-reactive protein, haptoglobin, alpha-1-acid glycoprotein, coeruloplasmin, transferrin, alpha-1-antitrypsin and plasminogen. There were small or no changes of albumin, alpha-2-macroglobulin and hemopexin. The elevations of the "acute phase reactants" were examined in three male subjects following a 2 h run before and after an endurance training period of 9 weeks. This demonstrated a decreased acute phase response after training as illustrated by the changes of C-reactive protein, haptoglobin and alpha-1-acid glycoprotein in spite of higher posttraining running speeds. Well-trained athletes have elevated levels of the serum protease inhibitors alpha-1-antitrypsin, alpha-2-macroglobulin and C1-inhibitor. These antiproteolytic glycoproteins might limit exercise-induced inflammatory reactions.

Adult↗
PubMed1977

Effects of 8 weeks' endurance training on skeletal muscle metabolism in 56-70-year-old sedentary men.

The effects of 8 weeks' endurance training on muscle metabolism at rest and after a submaximal bicycle ergometer exercise were studied in 31 previously sedentary men, aged 56-70. Training consisted of 3-5 one hour exercise bouts per week including walking-jogging, swimming, gymnastics and ball games. The effects of training were similar to those previously reported for younger men. Mean maximal oxygen uptake increased (11%), as did the resting values for muscle glycogen concentration, the enzymes representing aerobic energy metabolism (malate dehydrogenase, succinate dehydrogenase), and also some of the anaerobic enzymes (creatine phosphokinase, lactate dehydrogenase). Lactate production during submaximal work decreased. The enzyme activities were lower following acute exercise both before and after training.

Aged↗
PubMed1977

Submaximal working capacity, heart size and body size in boys 8-18 years.

Heart diameters, heart volume (HV), PWC130, VO2 at 130 heart rate, and cardiorespiratory reactions during work at 3 kgm-s-1 were obtained in 237 boys ranging in age from 8--18 years. Results indicate that heart size, PWC130, VO130, and exercise HR, VO2/HR, f and SBP change significantly with age. On the other hand, HV - kg-1 and work VO2, VE and VE/VO2 remain rather stable throughout the growth period. Correlation analysis indicates that about 85% of the observed variation in the size of the heart during growth can be accounted for by the body weight, while about 70% of the variation in light submaximal working capacity (VO130) can be explained by HV alone. Holding age, height and body weight constant by partial correlation procedures yeilds significant relationships between HV and VO130 (r = 0.461), and between HV - kg-1 and VO130 (r = 0.414). Age, height, weight and size of the heart correlated simultaneously against VO130 account for 75% of the variance in the dependent variable. It would seem important to suggest the need for study of the interactions between age, size and maturity, in addition to indicators of size and efficiency of the oxygen delivery system, and indices of muscle oxygen utilization efficiency. Such an approach will permit a more definite partitioning of the variance in submaximal aerobic capicity during growth, and would probably yeild a more conservative estimate of the relationship between the size of the heart and submaximal working capacity during growth.

Adolescent↗