[Pharmacokinetic studies with mexiletine in patients with renal insufficiency].
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Biomedical subjects
Publications and source records attributed to W Herbinger.
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In a review, clinical, phonocardiographic and cardioangiographic findings in mitral valve prolaps syndrome are discussed. Echocardiography is recommended as a noninvasive screening method for the diagnosis of this syndrome.
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A total of 710 blood samples was tested with the new Reflomat apparatus. There was a good correlation with the GOD-Perid method (correlation coefficient for serum r = 0.993; for whole blood r = 0.983). In two thirds of the cases deviation from the reference value was less than +/- 7 mg/dl for serum, less than +/- 14 mg/dl in 95%, the corresponding values for whole blood +/- 11 mg/dl and +/- 22 mg/dl, respectively. The percentage deviation from the reference value was below +/- 13% for serum, and under +/- 22% for whole blood in 95% of measurements. In the range under 100 mg/dl variations were much more marked for whole blood than at the higher levels (100-350 mg/dl). The accuracy of the Reflotest¿ system and the accuracy from day to day proved to be exceptionally good. In the range 100-200 mg/dl the variation coefficient was between 1 and 2%.
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