Biomedical subjects
Publications and source records attributed to W Heldwein.
This report concerns a 77 years old woman with a solitary metastasis of a bronchiogenic carcinoma to the humerus, which had been involved by previously diagnosed polyostotic M. Paget (ostitis deformans). The distinction from sarcomatous changes in Paget's disease is discussed.
157 patients with histologically investigated colorectal tumours from 5 hospitals of the University of Munich were tested with the Haemoccult test. In 30 (35.7%) of 84 patients with malignancy of the colon and in 31 (58.5%) of 53 patients with adenomas or polyps the correctly performed test was negative. The test result showed no dependency on age or sex of the patient, nor on size, stage or localisation of the tumour. A problem-orientated history lowered the rate of false negative tests to 2.4%. The high rate of false negative results was not attributable to organisational or technical errors.
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Mallory and Weiss (1929) described the syndrome which is characterized by hemorrhages from mucous membrane gaps of the cardia ner the esophagus. There are many causes responsible: sudden intraluminal pressure, obliteration of the mucous membrane, alcohol excess, voluminous meals, myocard infarction. In 3-5% hyperemesis is accompanied by Mallory-Weiss-Syndrome. For diagnosis endoscopy is the method of choice; if conservative therapy is without result, surgical measures are necessary. Lately endoscopic electrocoagulation gains more and more importance. 2 cases are reported.
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Rosacea fulminans is a rare disorder of unknown cause that mainly affects postadolescent women, with abrupt onset and disfiguring course if left untreated. The simultaneous occurrence of rosacea fulminans and inflammatory bowel disease is rare and has been reported predominantly in the setting of ulcerative colitis. We describe here a case of rosacea fulminans in a patient with Crohn's disease and discuss a possible association between the two conditions.