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Biomedical subjects

W Hassler

Publications and source records attributed to W Hassler.

88 records · Page 5Linked to original sources
PubMed1984

Intra- and perioperative aspects of the hemodynamics of supratentorial AV-malformations.

The risks which result from hemodynamic changes after surgery of 35 patients with supratentorial arterio-venous angiomas were investigated. With the help of a miniaturized 20 MHz Doppler probe flow and resistance were measured before, during, and after operations. The Doppler findings were compared with pre- and postoperative angiograms and intraoperative surgical findings. Postoperative angiograms were performed immediately after operation. The risk of haemorrhage and oedema was found to be high in cases of large vessels with slow flow and high resistance, in high flow angiomas, in stagnating arteries visible longer than 10 s and a length more than 6 cm, and in cases of pre-operative steal. These hemodynamic risky angiomas must be treated either by multiple step-operation or hypotension.

Blood Flow Velocity↗
PubMed1984

[Pediatric craniocerebral injuries requiring surgical treatment].

A survey is given of the craniocerebral traumas in children necessitating surgical treatment. The particularities of craniocerebral traumas in children are contrasted to those in adult persons. Diagnostic possibilities and consequences of the injury are discussed.

Brain Injuries↗
PubMed1983

Results and value of immediate postoperative angiography after operations for arteriovenous malformations.

Postoperative angiograms show immediate haemodynamic changes in large vessels, with a decrease in the diameter of the internal carotid artery and filling of vascular territories not previously injected. In 90% of the feeding vessels there is a disproportion between vessel lumen and flow after removal of the angioma. Mechanisms for adaptation exist, but they are inadequate in the immediate postoperative period. There is an increased risk of postoperative bleeding and brain swelling in patients with long feeding vessels, which are visible for longer than ten seconds in the angiogram.

Brain Edema↗
PubMed1979

[Traumatic sinus injuries and their operative treatment in the light of the normal anatomy of the cerebral sinuses and its variations (author's transl)].

In the light of our personal experiences, the present day possibilities of operative repair of sinus injuries are reported. The bases for such work is an exact knowledge of the topographical anatomy of the sinuses and its variations, which are described here. In addition to a historical survey of the development of the operative techniques the present-day procedures are described. The frequency and the prognosis are discussed.

Child↗
PubMed1978

Microsurgery of tumours of the frontal white matter.

Seventy eight microsurgical extirpations of tumours located in the frontal white matter led to adjustment of the normal anatomy of the frontal brain according to microsurgical requirements, and also to relation with modern diagnostic procedures, especially computerized tomography (CT-scanning). The advantages of microsurgical treatment have been demonstrated. Thus, only exact comprehension of topographical anatomy allows a methodical, careful, and radical procedure. As vessels were commonly saved, postoperative courses were relatively benign because of less tendency to oedema. Out of 78 patients, 3 died while in hospital, and two recurrences were observed in the following 23 months. Postoperatively 51 patients improved, 18 stayed unchanged neurologically, and 9 patients deteriorated permanently. The usual microsurgical instruments were employed. Vascular problems were dealt with by the routine techniques used at our hospital.

Astrocytoma↗
PubMedDate not supplied

Multiple intracranial tuberculomas with atypical response to tuberculostatic chemotherapy: literature review and a case report.

Approximately 34 cases of intracranial tuberculomas with paradoxical response to antituberculous chemotherapy have been documented worldwide. In most of the previously reported cases an associated tuberculous meningitis was reported. The majority of these patients were children or young adults, who had inoperable intracranial tuberculomas located in high risk regions that developed a few weeks or months after the start of an appropriate chemotherapy. Fifty-three percent of the patients recovered completely, 37% improved with mild neurological defects and 10% died. It is interesting that these intracranial tuberculomas developed or enlarged at a stage when systemic tuberculosis was being treated successfully. A recent experience with these potentially curable tumors of the central nervous system is reported. The literature is reviewed, and diagnostic and therapeutic considerations are discussed. The possible immunological mechanisms of this phenomenon are analyzed. In conclusion, patients who are suspected to have a CNS-tuberculosis should receive a prolonged (12-30 months) course of effective antituberculous therapy. The evidence of new intracranial tuberculomas or the expansion of older existing lesions does not indicate the need to change the antituberculous drug program. In such cases systemic dexamethasone as adjuvant therapy for 4 to 8 weeks is worthwhile and effective. Surgical intervention may be necessary in situations with acute complications of CNS tuberculosis, such as shunting procedures for the treatment of hydrocephalus. When the diagnosis is not ensured and there is no response to therapy within 8 weeks, a stereotactic biopsy on a suspected tuberculoma could be performed. If the largest lesion is not located in high risk deep regions of the brain, it could be totally removed surgically. With this combined management, a satisfactory outcome can be obtained in the majority of cases.

Adult↗
PubMedDate not supplied

[The slit ventricle syndrome--causes, differential diagnosis and therapeutic problems].

Shunt dependent patients with clinical signs of shunt malfunction and slit ventricles on computerized tomography could suffer either from low pressure or from a slit-ventricle-syndrome with increased pressure. In such cases we recommend a lumbal punction with pressure monitoring to make the diagnosis certain. In case of increased pressure we firstly inject 0.9% NaCl into the proximal part of the ventricular catheter to remove it's obturation. Sometimes shunt revision can so be avoided in the slit-ventricle-syndrome.

Adolescent↗
PubMedDate not supplied

[Growing septum pellucidum cyst in infancy].

We report a baby's development with expanding cyst of the septum pellucidum. It was detected accidentally during diagnostic evaluation of epileptic convulsions and psychomotoric retardation. The dramatic increasing of the cyst was followed by cranial ultrasonography for ten months. The progression of clinical symptoms couldn't be explained because after drainage of the cyst, no improvement took place. MRT with Spectroscopy lead to the tentative diagnosis, Morbus Alexander. This couldn't be proved because no biopsy of the brain was performed against the decision of the child's mother, nor postmortal (the child died at 20 months).

Cysts↗