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Biomedical subjects

W H Phoon

Publications and source records attributed to W H Phoon.

45 records · Page 3Linked to original sources
PubMed1982

A profile of silicosis cases who died.

Silicosis cases which had been notified by doctors and confirmed after investigations were followed up by the Industrial Health Division. Up to August 1981, a total of 313 persons were confirmed as having the disease. Of these, 59 had died. The majority of these 59 persons had had their silica exposure in the granite quarries. 13 had been exposed to "rubber powder" which contained a high percentage of free silica. 52 of those who died were male, and their average age at death was 60.87 years. This did not appear to be significantly shorter than their life expectancy of 65.1 years. But the average age of death for the 7 women was 58.86 years, which was much shorter than their life expectancy of 70 years. Many of the men died from causes unrelated to silicosis. But 6 of the 7 women had progressive massive fibrosis (PMF) and they apparently died of the disease or complications arising from it.

Adult↗
PubMed1980

An episode of trichloroethylene poisoning.

Trichloroethylene is commonly used in industry as a solvent and degreasing agent. An incident is described in which 14 out of 23 workers using trichloroethylene to clean machine parts in an electronics factory suffered symptoms of poisoning, including fainting in 3. Subsequent investigation showed the widespread use of trichloroethylene in that factory; containers of the chemical were also kept exposed. Industrial hygiene assessments revealed vapour levels which exceeded the permissible limit. The implementation of control measures brought the vapour levels to below 50 ppm, a safe level.

Adolescent↗
PubMedDate not supplied

Determination of cyclohexanol in urine and its use in environmental monitoring of cyclohexanone exposure.

A simple and sensitive method for determining urinary cyclohexanol, the main metabolite of cyclohexanone, by hydrolysis and gas chromatography (GC) with a flame ionization detector was developed. A 2-mL urine sample was hydrolyzed with 0.4 mL of concentrated HCl and followed by extracting twice with diethylether. Two microL of the filtrate was injected into the GC with a methyl silicone column. The detection limit is estimated to be 0.4 mg/L. The coefficient of variation for the procedure is 8% and 10% for the range of concentration 5 and 50 mg/L, respectively. The within-run variation was 5.4% and between-day variation was 9.67%. The method was verified with urine samples collected from workers exposed to cyclohexanone. An excellent correlation (r = 0.88) was observed between environmental cyclohexanone exposure and cyclohexanol in urine. The procedure is relatively simple and reproducible and it can be applied for occupational health measurement of cyclohexanone exposure.

Calibration↗