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Biomedical subjects

W H Hall

Publications and source records attributed to W H Hall.

At least 73 records · Page 4Linked to original sources

Rupture of the spleen in infective endocarditis.

A patient had delayed spontaneous rupture of the spleen complicating infective endocarditis. In 20 other cases reported through 1973, the most common presentation was found to be left upper quadrant pain followed by signs of peritoneal irritation and cardiovascular collapse. Abdominal paracentesis consistently yields free blood or pus in the peritoneal cavity; blood replacement and emergency splenectomy may be lifesaving. The basic pathological mechanisms may be (1) rupture of a mycotic aneurysm into the splenic substance (2) rupture of a splenic abscess, and (3) rupture of a suppurating intrasplenic vessel with hematoma formation, subcapsular dissection, and delayed capsular tear.

Endocarditis, Bacterial↗

Effect of L-asparagine on growth of Mycobacterium tuberculosis and on utilization of other amino acids.

l-Asparagine controls the utilization of other amino acids by Mycobacterium tuberculosis (H37Ra) in aerated, liquid synthetic media. In a mixture containing asparagine and either l-alanine or l-glutamic acid, amino acid utilization is diphasic, with asparagine being utilized first. Short-term growth rates and cell yields are diminished and mimic those seen with asparagine alone. Catabolite repression is the probable regulatory mechanism responsible for this effect of asparagine. In contrast, in the presence of aspartic acid, asparagine stimulates growth and increases utilization of aspartic acid.

Aerobiosis↗

Antibiotic susceptibility of Pseudomonas pseudomallei.

The in vitro activity of various antibiotics against Pseudomonas pseudomallei was studied. The tetracyclines were the most active, followed by gentamicin, kanamycin, novobiocin, chloramphenicol, rifampin, cycloserine, erythromycin, and ampicillin.

Anti-Bacterial Agents↗