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Biomedical subjects

W H Douglas

Publications and source records attributed to W H Douglas.

At least 37 records · Page 2Linked to original sources

Retention of adhesive cement on the tooth surface after crown cementation.

STATEMENT OF PROBLEM: Adhesive cements increase crown retention, but it is unknown if traces of cement remain undetected on the tooth surface after clinical removal of excess cement, which could exacerbate plaque retention. PURPOSE: This study measured the surface area, volume, mean depth, and maximum depth of a resin composite and a compomer luting cement left adherent on the tooth surface after removal of excess cement, as judged clinically. METHODS AND MATERIAL: Four groups of specimens (n = 48) were prepared for full coverage crowns: group AC bonding alloy with chamfer finish line, group G gold alloy with chamfer finish line, group PC porcelain with a chamfer finish line, and group PS porcelain with a shoulder finish line. Two profiles of the mesial and distal surfaces of the teeth were carried out: (1) tooth with crown seated but not cemented and (2) tooth with the crown cemented in place. Two cements and 2 methods of cement removal were studied. RESULTS: A 4-way analysis of variance for cement, crown type, method of removal, and tooth surface morphology showed that significantly greater volumes and mean depth, but not surface areas, of resin composite cement remained adherent than compomer cement (P<.05). Among crown types, significant differences were found for cement volume (group G>AC, G>PC, G>PS), cement surface area (group AC>PC, G>PC, G>PS), and maximum cement depth (group G>AC). There was no significant difference between the 2 methods of cement removal. Significantly larger surface areas and maximum depths of cement were retained on the anatomically grooved mesial surface of the maxillary first premolars than on the ungrooved distal surface. CONCLUSION: Subclinical cement retention occurred after crown cementation, which was influenced by cement, crown type, and tooth surface morphology but not method of cement removal.

Adhesives↗

Crack propensity of porcelain laminate veneers: A simulated operatory evaluation.

STATEMENT OF PROBLEM: Anterior teeth are especially subject to the thermal variations of ingested food and drinks. Postoperative cracks of porcelain laminates are considered a possible consequence of polymerization shrinkage, function, and thermocycling. PURPOSE: This investigation was conducted to define the parameters associated with the development of cracks in porcelain veneers using cyclic thermal fatigue. MATERIAL AND METHODS: Twenty-seven maxillary incisors were restored with porcelain laminate veneers and subjected to thermocycling (5 degrees C to 50 degrees C) for 1000 cycles. Ceramic cracks were reported for 11 of the 27 specimens. Teeth were sectioned and prepared for SEM analysis. Measurements of the ceramic and the luting composite thicknesses were performed for each specimen at different restoration locations (facial, incisal, and proximal). RESULTS: No significant differences in the ceramic or the luting composite thicknesses were observed between cracked and uncracked specimens. However, significant differences were observed in the ratio of the ceramic and luting composite thicknesses. Most cracked samples exhibited a ratio at the facial location below 3.0 (2.6 +/- 0.35), whereas most noncracked specimens were above this value (3.9 +/- 0.19). Incisal and especially proximal measurements alone were not significantly different between cracked versus uncracked specimens. Ceramic was slightly thinner in the facial aspect than in the proximal aspect, which was also thinner than the incisal aspect. Composite in the facial aspect was thinner in the cervical area than in the incisal third of the tooth. CONCLUSIONS: Significant cyclic temperature changes can induce the development of flaws in porcelain veneers. Control of tooth reduction and the application of die spacers during laboratory procedures undoubtedly represent key elements; a sufficient and even thickness of ceramic combined with a minimal thickness of luting composite will provide the restoration with a favorable configuration with regard to crack propensity, namely, a ceramic and luting composite thickness ratio above 3.

Analysis of Variance↗

Effect of luting composite shrinkage and thermal loads on the stress distribution in porcelain laminate veneers.

STATEMENT OF PROBLEM: Cyclic thermal fatigue has demonstrated a significant influence of the thicknesses of luting composite and ceramic in crack propensity of porcelain laminates. PURPOSE: This study was conducted to define potentially involved parameters for crack development in porcelain laminates bonded to teeth. Finite element modeling was used to evaluate the respective effects of luting composite shrinkage and significant thermal changes. MATERIAL AND METHODS: A buccolingual cross-section of a maxillary incisor was digitized and used as a template to generate a single 2-dimensional mesh, including all the different restorative designs. Luting composite shrinkage was simulated at a baseline temperature of 20 degrees C. The effect of thermal loads from 20 degrees C to 5 degrees C and from 20 degrees C to 50 degrees C was assessed with and without preexisting composite shrinkage. RESULTS: Shrinkage of the luting composite alone generated important compressive forces on the ceramic, either at the restoration surface or interface. Compression intensity was related to geometry and ratio of thicknesses between the ceramic and luting composite (CER/CPR). Lower ratios produced higher compression forces in the ceramic. When thermal loads were combined to the composite shrinking forces, the stress pattern was significantly changed only for the experimental conditions with the lowest CER/CPR ratio. Temperature increase reduced compressive stresses and exacerbated tensile stresses. Thermal loads were simulated alone (situation of an "ideal nonshrinking" luting composite) and generated mainly tensile stresses in the ceramic, which intensity was again modulated by the CER/CPR ratio and the local geometry of composite and ceramic. Because of ceramic brittleness, these tensile forces were more detrimental than the high compression created by composite shrinkage alone. The stress pattern was not influenced by the incisal length of the veneer but rather by the facial thickness of ceramic. The worst record made with a shrinking luting agent (500 microm of luting composite, lowest CER/CPR ratio, 5 degrees C) was much less harmful than the worst record made with a hypothetical "nonshrinking" luting material. CONCLUSIONS: The ratio of the thickness of cement and luting composite appears to have a relevant influence on the stress distribution in porcelain laminates. Restorations that are too thin, combined with poor internal fit, resulted in higher stresses at both the surface and interface of the restoration. Because of its precompressed state given by composite shrinkage, ceramics performed better with regard to temperature-induced tensile forces.

Ceramics↗

Rationalization of incisor shape: experimental-numerical analysis.

STATEMENT OF PROBLEM: Moving from the posterior segment in the anterior direction within the dental arch, the process of "incisivization" takes place. The occlusal table is gradually replaced by an incisal edge that has the function of cutting. PURPOSE: This study considers these genetically controlled changes by using strain gauge measurements and finite element analyses to rationalize the clinical and biologic advantages of incisal form. A direct clinical link in the common esthetic procedure of anterior veneering is expected. MATERIAL AND METHODS: Six maxillary incisors were mounted in a positioning device and equipped with 2 strain gauges bonded to the palatal surface: gauge 1 (G1) in the concavity and gauge 2 (G2) on the cingulum. A 50 N load was applied on the palatal side of the incisal edge, perpendicular to the long axis of the tooth. Displacement of the load tip and the palatal strain were recorded after successively removing one third, two thirds, and the total thickness of the facial enamel. The same experiment was reproduced with the finite element method (FEM). Four additional experimental designs were tested with the FEM by simulating the progressive thinning and elimination of palatal enamel and a thickened palatal lobe. Surface tangential stresses and local strain in the area corresponding to gauges 1 and 2 were calculated from the postprocessing files. RESULTS: The FEM was validated by experimental results considering both displacement of the load tip ( approximately 120 +/- 30 microm) and tangential surface strain at G1/G2. Recorded strains were always higher in the concavity when compared with the cingulum; high tensile strains were recorded at G1 after the total removal of the facial enamel. The entire facial surface was submitted to compressive forces. Subsequent compressive stresses were higher ( approximately 150 MPa) when facial enamel was thin or when the palatal enamel was removed. However, their absolute value never reached the elevated and potentially harmful tensile stresses measured in the palatal concavity, especially in the absence of facial enamel (272 MPa). Multiple experimental cracks were generated in the remaining palatal enamel as a consequence of stress redistribution. However, smooth and convex surfaces with local enamel bulk such as the cingulum, the marginal ridges, and the facial cervical third of the anatomic crown showed the lowest stress level. The optimal configuration with regard to the stress pattern was given by the modified natural tooth that exhibited thick palatal enamel and a mostly convex palatal surface. CONCLUSIONS: Palatal concavity that provides the incisor with its sharp incisal edge and cutting ability proved to be an area of stress concentration. This shortcoming can be compensated by specific areas that feature thick enamel such as the cingulum and the marginal ridges. When enamel is worn or removed from the facial surface, its replacement should be carried out by using materials with properties similar to enamel to restore the original biomechanical behavior of the tooth.

Compliance↗

Fracture toughness of conventional, resin-modified glass-ionomer and composite luting cements.

OBJECTIVES: This study was conducted to determine if significant differences existed between the fracture toughness of three types of luting cement, and, if the method of mixing conventional glass-ionomer luting cements, hand-mixed or mechanically mixed, influenced the value obtained. METHODS: Three types of luting cement were investigated: conventional glass-ionomer cement (two handmixed and two capsulated cements, KetacCem, Fuji I and KetacCem Maxicap, Fuji Cap I), a resin-modified glass-ionomer cement (Vitremer Luting Cement) and a resin composite cement (Scotchbond Resin Cement). Eleven specimens of each of the six cements were fabricated to determine the plane strain fracture toughness using the chevron notch short rod technique. After seven days the specimens were loaded in a water bath, at a crosshead speed of 4 microns/s and the fracture toughness values calculated. RESULTS: ANOVA indicated significant differences between the cements (p < 0.0001) and each cement was compared with all others using Fishers PSLD test (p < 0.05). The rank order of results from highest fracture toughness value to lowest (mean +/- s.d.) was Scotchbond Resin Cement (1.31 +/- 0.17), Vitremer Luting Cement (1.08 +/- 0.1), Fuji Cap I (0.37 +/- 0.04), KetacCem Maxicap (0.37 +/- 0.05), Fuji I (0.34 +/- 0.04), KetacCem (0.27 +/- 0.03). SIGNIFICANCE: Of the cements tested, the resin composite cement is most likely to resist clinical failure by cement cohesive failure.

Analysis of Variance↗

Comparison of two measurement techniques for clinical wear.

OBJECTIVES: Clinical wear of restorations is generally evaluated by marginal integrity over time. In this study, both a subjective and an objective method for wear assessment are compared, and the relative advantages and disadvantages of each are considered. METHODS: A surface evaluation technique for quantitative measurement of wear, as developed at the University of Minnesota (UMN) has been compared to the commonly employed method of wear assessment used by Leinfelder (LF). Measurements were made by comparing suitable casts of restored teeth before and after clinical function. Semi-quantitative wear assessment was studied in comparison with detailed quantitative information about the topology of the pre- and post-wear occlusal surfaces obtained from stylus profilometry and processed by imaging techniques. Fourteen model sets of baseline, 2, 3 and 5 year old Class II composite restorations from a Danish clinical trial were evaluated using both techniques. RESULTS: In general, after 5 years of function, the digitizing method (UMN) generated wear values that were twice as high, indicating that general wear of restorative materials is underestimated by the LF-method. CONCLUSIONS: The comparison clearly revealed the advantages and limitations of each technique. Evaluation of wear by means of the LF technique provides global semi-quantitative data on restoration margins relative to enamel, underestimating general wear of the restorative material. Advanced 3-D measuring techniques such as the UMN method provide extensive quantitative data regarding wear patterns of the entire occlusal surface, i.e. restoration and enamel. Such a highly accurate technique is capable of differentiation between wear behavior of restorative materials early on in clinical studies. In addition, through its digital alignment procedure, the UMN method provides data on accuracy of the replication process used in clinical studies.

Analysis of Variance↗

Rationalization of esthetic restorative dentistry based on biomimetics.

UNLABELLED: The exponential progressivism that characterizes the current decade often comes with substantial financial implications. Dental care is not spared by this phenomenon. However, new generations of concepts emerging from biomimetics provide the operator with the ability to restore the biomechanical, structural, and esthetic integrity of teeth. The development of adhesion and the evolution of porcelain veneers constitute striking examples of this nascent process. Indications for bonding porcelain are extending to more perilous situations (crown-fractured incisors, nonvital teeth), resulting in considerable improvements, comprising both the medical-biologic aspect (economy of sound tissues and maintenance of tooth vitality) and the socioeconomical context (decrease of costs compared to traditional and more invasive prosthetic treatments). CLINICAL SIGNIFICANCE: In the bonded porcelain veneer and its extensions, restorative dentistry has found new solutions for the anterior segment that balance the need for functional and esthetic reconstruction. The optimal stiffness of porcelain in thin section, the ideal surface characteristics, and the biomechanical continuum achieved through high performance bonding mean the crown of the tooth as a whole can support incisal or masticatory function. By the same token, the conduction of optical effects from within the tooth combined with the ideal surface features of the porcelain veneer make this restorative approach the ultimate in esthetic satisfaction, for both the practitioner and the patient.

Cuspid↗

Design optimization and evolution of bonded ceramics for the anterior dentition: a finite-element analysis.

OBJECTIVE: Finite-element method was used to explore the stress distribution of incisors restored with porcelain veneers. The design of the incisal palatal finish line was analyzed as a function of incisal overlap and initial tooth substance loss (coronal fractures). METHOD AND MATERIALS: The treatment of intact and fractured incisors was investigated using 8 different designs of porcelain veneer. The palatal finish line varied from butt margins to extended chamfers. The stress distribution was assessed in a 2-dimensional finite-element model, reproducing a buccolingual cross section of an incisor. A palatal 50-N horizontal force was applied to the incisal edge to simulate an extreme functional load. The palatal surface tangential stresses were calculated. RESULTS: Considerable differences were detected in the stresses at the level of the incisal-palatal restoration margin. The margins of restorations with limited incisal overlap (butt margin or minichamfer) showed low tensile stresses or even compressive stresses. Restorations with a long chamfer extending into the palatal concavity were subjected to the highest tensile stresses. In the presence of moderate crown fractures (incisal one third) or severe wear, butt margins limited the palatal extension of ceramic, thus reducing the amount of stress at the restoration interface. In the presence of severe crown fractures (incisal two thirds), the margins (either butt or chamfered) were subjected to low tensile forces when located in the smooth convex area of the cingulum. CONCLUSION: Because of the geometry and natural elastic modulus of mineralized tooth structures, a concentration of tensile stresses is formed at the palatal concavity of teeth restored with porcelain veneers. Long chamfers extending into the palatal concavity are unfavorable because thin extensions of ceramic are generated in an area of maximum tensile stresses. Minichamfers or butt margins are generally recommended, especially in the presence of moderate crown fractures or severe wear.

Compressive Strength↗

Optimization of resilience and stress distribution in porcelain veneers for the treatment of crown-fractured incisors.

The present study was conducted to define, when restoring extensive loss of dentin, the configuration of the restoration that will best reproduce the biomechanical properties of the intact original tooth in terms of resilience and stress distribution. The treatment of 1/3-crown fractures and 2/3-crown fractures was investigated using different designs of facial porcelain veneers with and without underlying composite buildup. The stress distribution and tooth compliance were assessed in a numeric model reproducing a 2-dimensional buccolingual cross section of an incisor. A 50-N facial force was applied to simulate an incisal impact situation. The facial surface tangential stresses were calculated, and the maximum displacement (horizontal direction) at the most incisal node of the enamel surface was also recorded and used to calculate the tooth compliance (i.e., displacement/load or resilience) for each test condition. Tensile stresses were generated on the facial surface of the porcelain laminates with a similar pattern for all test conditions, the cervical part of the crown being the most quiescent area. Substantial differences appeared in the incisal half of the crown, the lowest stresses being observed for extensively fractured teeth restored without composite buildup (facial peaks at approximately 33 MPa). Fractured teeth restored with minimal veneers and a "dentin-like" composite buildup showed stress patterns similar to the intact tooth (facial peaks at approximately 50 MPa). The natural tooth gave the highest tooth compliance or flexibility. All restorative designs featured increased tooth stiffness. However, the original tooth compliance was almost restored when composite was used to replace the missing dentin, with the porcelain acting only as a facial and incisal enamel substitute. When restoring crown-fractured incisors, tooth compliance and stress distribution can be modulated by the combination of composite and ceramics. Optimized configurations can be reached to reproduce the original biomechanical behavior of the intact tooth. The use of ceramic alone generates low stress concentrations, but also less compliant restored teeth.

Biomechanical Phenomena↗

Additive contour of porcelain veneers: a key element in enamel preservation, adhesion, and esthetics for aging dentition.

Esthetics and function are equal concerns when restoring the anterior dentition. Modern concepts in restorative dentistry have brought new solutions through bonded porcelain veneers that are stress distributors and involve the crown of the tooth as a whole in supporting occlusal force and masticatory function. This recovery of the original biomechanics of the intact tooth, the biomimetic principle, is particularly valuable when considering the restoration of an aging dentition. Both function and appearance are affected by the senescent changes of the aging teeth. Erosion and surface wear lead to a progressive thinning of enamel, ultimately leading to increased crown flexibility and higher surface strains. It appears therefore that the restoration of tooth volume will not only re-establish the original and youthful appearance of the smile but will also allow the biomimetic recovery of the crown. The final treatment outcome strongly depends on the therapeutic approach chosen, the driving force of which should be the preservation of the thin remaining enamel. While a number of preparation techniques will expose dentin to a great extent, the principle of enamel preservation can still be fulfilled by the use of a specific approach. This article describes a treatment method which includes the use of a diagnostic template. This type of work strategy, documented with clinical cases, integrates additive wax-ups and acrylic mock-ups. The latter will provide a significant amount of diagnostic information and economy of tooth substrate, the importance of which cannot be overestimated in the completion, functionality, and longevity of the final restoration.

Acrylic Resins↗

Spatial chemical analysis of dental stain using wavelength dispersive spectrometry.

Six extracted human teeth with naturally-formed neglected stain were analyzed for chemical constituents using wavelength dispersive spectrometry (WDS), an electron microprobe technique. Spatial distribution, within a few microm resolution, of the compositional elements was obtained by line and map analyses, which provided relative concentrations of the elements in stain-enamel complex. Absolute concentrations at different locations across a specimen were obtained from quantitative analysis. Results showed that these neglected stains were highly calcified and contained a significant amount of organic matter (C, N, O, S), with traces of Fe and Cu. The tooth surface underneath the stain layer could be easily distinguished by the higher Ca and P content, as well as by finite amounts of C and S. Corresponding areas of high concentrations between S and Fe/Cu were observed, which suggested the complex of sulfur and metal ions as possible color-forming species. S was found to diffuse into surface enamel in the range of 10 microm.

Calcinosis↗

Do dental composites always shrink toward the light?

Many of the current light-curing composite restorative techniques are rationalized in compliance with the theory that composite shrinks toward the light. Shrinkage directed toward the margins is believed to be responsible for the observed improved marginal properties. However, the dental literature does not consistently support this theory. Experimental determination of contraction patterns is very difficult. In this study, a finite element technique is used to analyze the direction of composite shrinkage as it cures. The process of polymerization can be characterized by pre- and post-gel phases. The stress developed in a restoration can be relieved quickly by the flow of material still in the pre-gel phase. Residual stresses arise after gelation. Both auto- as well as photo-curing composites were analyzed. In photo-curing composites, the gel-point varies throughout the material with the intensity of the light. Experimentally determined light transmittance data for different materials were used in the simulation. Degree of cure and time-dependent shrinkage properties were also included from experimental measurements. The analysis showed that the shrinkage direction was not significantly affected by the orientation of the incoming curing light, but instead was mostly determined by the bonding of the restoration to the tooth and by the free surfaces. Consequently, differences between the contraction patterns of auto- and photo-cure were minimal. It was concluded that composite does not shrink toward the light, but that the direction is predominantly determined by cavity shape and bond quality. Improved marginal properties should be pursued by the optimization of other factors, such as the polymerization process, the curing procedure, and the bond quality. The direction of shrinkage vectors in response to light position does not seem to be an appropriate criterion for the optimization of marginal quality.

Animals↗

The future of dental materials.

This article reviews some of the rapid developments in dental materials that have occurred during the last 25 years, especially adhesive, biocompatible and aesthetic materials. Some innovative research developments, which have exciting possibilities for future dental treatment, are outlined.

Biocompatible Materials↗

Stain removal efficacy: an in vitro evaluation using quantitative image analysis.

OBJECTIVE: This study developed a computer image analysis technique as a quantitative means to measure changes in dental stain after brushing with various dentifrices. METHOD AND MATERIALS: Enamel specimens with naturally occurring mature stain were cut from bovine incisors. The specimens were subjected to in vitro toothbrushing with one of the four tested groups, consisting of two dentifrices that make claims of stain removal (Aquafresh Whitening and Rembrandt Sensitive), a regular dentifrice, (Aquafresh Triple Protection), and water. Digital images of stain specimens were recorded under standardized lighting conditions and analyzed with an image analysis software. The area-intensity stain determinant, which accounted for the reflected intensity and the corresponding areas of stain, was computed. Stain removal efficacy was calculated based on the difference in area-intensity stain determinant before and after brushing. RESULTS: Brushing with any of the tested dentifrices removed more stain than did brushing with water alone. The finding that brushing with a regular dentifrice resulted in higher stain removal efficacy than brushing with water seems to indicate a role for abrasivity. Aquafresh Whitening had a higher stain removal efficacy than did Rembrandt for the removal of mature calcified stain used in this study. However, there were certain stains that none of the dentifrices removed. CONCLUSION: Computer image analysis provides an objective and quantitative measurement to distinguish in vitro stain removal efficacy of dentifrices.

Analysis of Variance↗

Variation in tooth wear in young adults over a two-year period.

STATEMENT OF PROBLEM: Although all the processes of loss of hard tissue are important, attrition on the occlusal surfaces commands our attention. PURPOSE OF STUDY: The enamel wear rate of 18 young adults over 2 consecutive years was measured independently by volume loss and mean depth loss. Any significant differences in tooth wear resulting from gender and a clinical diagnosis of bruxism were identified. MATERIAL AND METHODS: A strict protocol for dental impressions provided epoxy models, which were digitized with a null point contact stylus. AnSur software provided a complete morphologic description of changes in the wear facets. RESULTS: The mean loss for all teeth measured was 0.04 mm3 by volume and 10.7 microns by depth for the first year. CONCLUSIONS: These numbers were approximately doubled at 2 years of cumulative wear.

Adult↗

Analysis of strain gage method for measurement of post-gel shrinkage in resin composites.

OBJECTIVE: The objective of this study was to refine a strain gage method for measuring polymerization contraction of resin composites and to isolate the net post-gel contraction by identifying factors contributing to the measured strains. The hypothesis to be tested was that carefully controlled strain gage measurements of composite polymerization could isolate post-gel contraction events. METHODS: Composite was placed on a biaxial strain gage and light-cured. This method enabled real-time registration of the progress of shrinkage strain, corresponding to elastic modulus development. Strain from the two axes of the strain gage were averaged and plotted as a function of time. A representative curve was calculated from the mean of ten measurements. The following factors influencing the total contraction measurement were evaluated: thermal expansion of the gage, thermal expansion of the composite due to the exothermic reaction and exposure to the curing light, and adhesion of the composite to the gage. These parameters were measured so that the net deformation of the composite during polymerization could be calculated. RESULTS: Parametric studies of pre-cured and photointiator-free materials confirmed the hypothesis that strain gages measure post-gel contraction. Thermal artifacts were measured and subtracted from the total strain output. SIGNIFICANCE: Strain gages are suitable for measuring the clinically significant phase of composite polymerization contraction.

Adhesiveness↗

Comparison of the porosity of hand-mixed and capsulated glass-ionomer luting cements.

The strength of dental glass-ionomer cements will be influenced by defects present within its structure. This study measured the surface area porosity, percentage surface area porosity, and mean surface area of small bubbles (<0.01 mm2) and the surface area porosity, percentage surface area porosity and diameter of large bubbles within 40-microm-thick layers of four cements, using image analysis software. Two hand-mixed cements (Fuji I and KetacCem) and two capsulated cements (Fuji Cap I and KetacCem Maxicap) were viewed under transmitted light at x117.6 magnification. For each selected area (64.75 mm2) of each cement sample, five independent measurements were made of each of these parameters. Analysis of variance (ANOVA) indicated that there were no significant differences between the four cements in the small bubble parameters measured, whilst there were significant differences in the surface area porosity, percentage surface area porosity and diameter of the large bubbles. It was concluded that the hand-mixed cements tested had a greater number of larger diameter bubbles compared with the capsulated cements.

Analysis of Variance↗

Inhibitive effect of a resin-modified glass ionomer cement on remote enamel artificial caries.

Glass ionomer cements (GICs) demonstrate the inhibition of caries lesions formed immediately adjacent to the restoration. This in vitro study was conducted to evaluate the distance at which a resin-modified GIC is able to exert its cariostatic effect on artificial enamel lesions ('remote effect'). Resin-modified GIC or bis-GMA resin was applied on the cervical third of the labial surface of 10 paired halves of bovine incisors. Specimens were separately immersed for 3 weeks in lactic acid gel which was changed every other day to reduce fluoride accumulation. Artificial lesions were examined by the cross-sectional microhardness (MHN) method. Volume percent mineral, mineral loss (delta Z value) and change in mineral content (delta M) were computed for each MHN profile, performed at distances of 0.2, 0.5, 1.0, 2.0, 4.0 and 7.0 mm from the edge of the materials. delta Z values of the resin-modified GIC group were significantly lower than those of the bis-GMA control group at all remote sites (t test, p < 0.05). The delta M caused by resin-modified GIC was more pronounced within 1.0 mm from the material which suggested that the demineralization inhibition can be divided into the near effect (< 1.0 mm). In this in vitro study, resin-modified GIC provided caries resistance in bovine enamel located at a considerable distance from the margin of the material.

Animals↗