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Biomedical subjects

W H Annesley

Publications and source records attributed to W H Annesley.

At least 37 records · Page 2Linked to original sources

Krypton red laser photocoagulation of subretinal neovascular membranes located within the foveal avascular zone.

Fifty-one eyes with senile macular degeneration and a well-defined subretinal neovascular membrane located within 250 microns from the center of the foveal avascular zone were treated with krypton red laser photocoagulation. Follow-up ranged from 8 to 18 months (mean, 10 months). The eyes were divided into two groups based upon the location of the neovascular membrane. Group I (juxtafoveal membrane 1 to 250 microns from the center of the foveal avascular zone) contained 26 eyes. Following treatment the visual acuity in 16 of the 26 eyes (62%) improved by two or more lines on the Snellen chart or stabilized. Group II (subfoveal membrane present under the center of the foveal avascular zone) contained 25 eyes. Following treatment only 7 of 25 eyes (28%) improved by two or more Snellen lines or maintained their pretreatment visual acuity. Of 16 eyes that had a pretreatment visual acuity of 20/100 or better, only 2 eyes (12%) remained in this group following treatment.

Aged↗

Optic disc edema in the presumed ocular histoplasmosis syndrome.

Two patients with presumed ocular histoplasmosis syndrome developed optic disc edema. In both cases the edema resolved without residual impairment of visual function. Although peripapillary changes in ocular histoplasmosis are common, optic disc edema is rare. The pathogenesis of the edema is unknown.

Adult↗

Central serous chorioretinopathy: a seasonal variation?

A review of 345 consecutive cases of patients under the age of 40 years with central serous chorioretinopathy seen between 1969 and 1979 was performed in order to define temporal patterns of occurrence. The monthly distribution of cases significantly differed (p less than 0.01) from an expected random distribution. Although a statistical trend analysis failed to confirm a definite seasonal variation (p less than 0.01), an increased number of cases were seen in March and April.

Adult↗

Retinal pigment epithelial tears.

Retinal pigment epithelial tears have been recognized recently as a complication of retinal pigment epithelial detachments. They are characterized by sudden separation of detached from attached pigment epithelium at the margin of the detachment. Retraction of the overlying pigment epithelium occurs and exposes Bruch's membrane and choroid. Most pigment epithelial tears appear to arise spontaneously, but they also may occur following krypton red laser photocoagulation. The visual prognosis is poor in eyes in which the tear involves the subfoveolar pigment epithelium.

Aged↗

Familial pars planitis.

Pars planitis has rarely been noted to occur in more than one member of a family. We report the occurrence of this disorder in more than one member of two unrelated families. The affected members of one of these families included a 37-year-old woman and three of her six children. The affected members of the other family were two teenaged brothers. No specific cause for the familial clustering of pars planitis has been identified in the affected members of these families.

Adolescent↗

Familial exudative vitreoretinopathy.

Fifteen patients in three families with familial exudative vitreoretinopathy were examined and followed. Eleven of the 15 (73%) were asymptomatic and showed only peripheral non-vascularization of the peripheral temporal retina. An acute proliferative form resembling acute retrolental fibroplasia was characterized by dragging of the retina to the temporal side and subretinal exudation which developed in children between the ages of birth and ten years. The acute proliferative changes in pediatric patients typically occurred asymmetrically, with one eye remaining asymptomatic or less severely affected while the other eye progressed to severe temporal dragging of the retina, subretinal exudation, and retinal detachment.

Adolescent↗

Vitrectomy and cystoid macular edema.

Twenty-two patients who underwent vitrectomy surgery for chronic cystoid macular edema (CME) were evaluated. These patients all had uneventful intracapsular cataract extraction, but CME with vitreous adhesions to the cataract incision later developed. Vitrectomy was performed to remove the vitreous from the anterior segment structures in each case. Nineteen of the 22 patients showed improved visual acuities within six months, and all but two had complete resolutions of the CME by one year. These two patients did show marked improvements of visual acuity. The majority of patients younger than 65 years of age had final visual acuities of 20/50 or better, whereas the majority of those older than 65 years had less than 20/50. The results were not influenced by the duration or the pattern of the CME prior to vitrectomy. A prospective study to determine the value of vitrectomy in this type of patient is suggested.

Aged↗

Macular branch vein occlusion.

Occlusion of a small macular tributary branch vein, not involving a major arcade, can be extremely subtle and the correct diagnosis is frequently missed. Capable of adversely affecting central visual acuity, macular vein occlusion has a variable clinical presentation and course which may elude more conventional examination techniques and require fluorescein angiography to confirm or establish its presence. Recognizing the need for increased awareness of this disorder, emphasis is placed on orientation through case presentations depicting the clinical and angiographic features of this subgroup of branch retinal vein occlusions. A retrospective evaluation of the clinical data and angiographic features of 75 individuals with macular branch vein occlusion permitted evaluation of 64 patients with follow-up ranging from two months to ten years. Various forms of medical therapy were used in the management of many of these individuals, but argon laser photocoagulation was only used in 22 patients. The limitations inherent in interpreting data from uncontrolled studies are acknowledged. Our observations support the need for recognition and intensive evaluation of this special group of vein occlusions.

Adult↗

The clinical course of serpiginous choroidopathy.

We closely observed nine patients (17 eyes) with serpiginous choroidopathy for time periods ranging from two to ten years. There were seven men and two women with ages ranging from 22 to 58 years, average age was 46 years. Eight patients were bilaterally affected; one patient had only one eye. The clinical course of the disease was characterized by multiple recurrences. The recurrences and progression of the disease often were not noticed by patients if the macular area was not involved. Serial fundus photographs proved to be invaluable in establishing progression. Although the disease usually progresses in a centrifugal manner from the disk toward the periphery, three patients demonstrated centripetal progression and one of these three permanently lost central acuity. Visual acuity was affected only when the foveal or parafoveal areas became involved, but in nine of the 17 eyes, visual acuity returned to a variable degree. None of the patients had any general systemic illness. However, five of the patients reported chronic exposure to an unusual variety of chemicals.

Adult↗

An alternative method of gas-fluid exchange through the limbus in giant tears and other complicated retinal detachments.

An alternative method of gas-fluid exchange through the limbus in patients with giant tears and complicated retinal detachments is presented. The indications for the combined surgery of scleral buckle, vitrectomy, and gas-fluid exchange are suggested. The results of this type of surgery in 5 patients with giatn retinal tears, and in 12 patients with complicated retinal detachments, are reported. Most failures were caused by massive periretinal proliferation.

Air↗

Varix of the optic disk.

A 74-year-old woman had a saccular dilatation, presumably of the central retinal vein, on the optic nerve head. The lesion caused no symptoms, and over a four-month period showed (vidence of thrombosis and stagnation within it. The lesion caused no interference with either the arterial or venous circulation of the retina. We advised no treatment and continue to observe the patient.

Aged↗

Necrotic melanocytoma of iris with secondary glaucoma.

A 23-year-old white man had a pigmented iris tumor that was not enlarging; it produced satellite iris lesions, diffuse pigmentation of the trabecular meshwork, and secondary glaucoma. Although enucleation was initially recommended, we chose to remove only the primary lesion with a sector iridectomy. Histologically, the lesion proved to be a benign melanocytoma that had undergone extensive necrosis. Postoperatively, the satellite lesions, pigmentation in the angle, and glaucoma all resolved.

Adult↗

Presumed ocular histoplasmosis syndrome. The fellow eye.

The fundus photographs of 308 patients with presumed ocular histoplasmosis syndrome (POHS) were examined. Bilateral macular involvement was found in 20% of the cases. The incidence of maculopathy, peripapillary lesions, and peripheral "punched-out" lesions in one fundus and only peeipapillary changes in the fellow eye was 12%. The incidence of these features in one fundus and clinically inactive, atrophic scars in the posterior pole of the fellow eye was 23%. Twenty-five patients with atrophic lesions in the macular area of the fellow eye were followed for an average of 24 months. Six patients (24%) demonstrated activation of eight previously documented atrophic lesions resulting in macular involvement. One patient also demonstrated activation from a pre-existing juxtapapillary lesion. None of the remaining 18 patients exhibited any evidence of serous or hemorrhagic retinal sequelae in the fellow eye.

Adolescent↗

Intraocular microsurgery: I. New instrumentation (SITE).

The SITE instrument appears to combine advantages of other instruments previously described. It meets the proposed objectives of an efficient cutter where tissue is removed at the front end of the tip. It allows the surgeon complete control of the suction and reflux systems. The instrument is of a simple modular dsign. A fiber optic attachment is available. It is dependable and safe.

Animals↗