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Biomedical subjects

W Gregoir

Publications and source records attributed to W Gregoir.

At least 19 recordsLinked to original sources

[Prostate hypertrophy. Surgical experience in Belgium. Multi-center study of 1,140 patients of 80 years and older].

An inquiry organized by the Belgian Society of Surgery brought data on the mortality and morbidity of surgery on patients of 80 years and older for benign prostatic hypertrophy in a total number of 1,140 operations. Consensus exist to see this surgery as planned surgery. The mortality was 73 (6.3%) without statistical difference between endoscopic and open surgery. The morbidity of 824 patients was 165. This last figure relates to the big series in the literature. The mortality is in direct relation to the age of the patients. Evaluation of cardio-pulmonary risk (70.8% of the mortality), operation on indication at earlier diagnosis and prospective studies on the risk of operation in this population group are indicated.

Aged

Prevention of postoperative deep-vein thrombosis by low-dose heparin in open prostatectomy.

A double-blind trial was designed to investigate the efficacy of low-dose heparin in preventing deep-vein thrombosis (DVT) after open prostatectomy... The diagnosis of DVT was established by the 125I-fibrinogen test. The incidence of DVT was 39.4% in the control group (33 patients) and 9.7% in the heparin group (31 patients) (p less than 0.01). These results suggest that low-dose heparin effectively prevents DVT after open prostatectomy

Aged

Ureteral stasis in cervicoprostatic obstructions.

A urodynamic study of patients with prostatic adenoma or other types of cervicoprostatic obstructions demonstrate that ureteral stasis is not a consequence of a direct compression of the intramural ureter by the adenoma but is secondary to dynamic disturbances.

Constriction, Pathologic

The trigonointestinal implantations.

The author reports the indications, operative technique and long-term results of trigonosigmoidostomy in 26 cases of bladder exstrophy. The long-term results were considered as excellent in 20 cases, satisfactory in 4 and bad in 2. Even after a long period of up to 20 years, the function of the ureterotrigonal junction remains intact and ascending pyelonephritis does not occur. Social life is normal and sexual function is possible. In cases when internal diversion is counterindicated, the trigone can be successfully implanted into an isolated loop of the ileum or colon.

Adolescent

Selective pudendal arteriography.

Selective pudendal arteriography is indicated in selected cases of male impotence when there is a strong presumption that peripheral arterial lesions are responsible for it. These lesions are classified as: (a) traumatic; (b) obstructive in thrombo-angiitis or atheroma, and (c) dysplasic. Selective arteriography will confirm the diagnosis and indicate the nature of the obstruction, its degree and extension.

Adult

Exstrophy of the bladder: treatment by trigonosigmoidostomy--long-term results.

Twenty-five patients with bladder exstrophy were treated by implanting the vesical trigone into the sigmoid colon. Twenty-three have been followed for 3 to 19 years, with an average of 10 years. Taking into account the clinical status, renal function, the intravenous urogram, continence and social life, 18 patients were considered to have had an excellent result. There were 2 failures; 1 post-operative death occurred due to ruptured oesophageal varices and 1 patient developed bilateral hydronephrosis which necessitated cutaneous urinary diversion. In 4 cases the results, while satisfactory, were only fair in that 2 developed stones and 2 showed symptomatic electrolyte disturbances requiring treatment. Trigonosigmoidostomy preserves intact the ureterovesical junction which prevents colo-ureteric reflux and this probably accounts for the generally excellent long-term results. We believe the operation is preferable to ureterosigmoidostomy in the management of bladder exstrophy.

Adolescent

Haemostatic prostatic adenomectomy.

1,500 cases of retropubic adenomectomy with preventive ligation of the prostatic arterial pedicles and trigonisation of the posterior urethra are presented. The technical details are described. The mortality rate is 0.7%. One of the most frequent complications is pulmonary embolus, lethal in only 0.3% of the cases. In moderate and large adenomas, by the efficiency of haemostatic control and the quality of the late results, the procedure has given more satisfaction than other types of surgical or endoscopic adenomectomies.

Arteries

[Extravesical antirefluxplasty (author's transl)].

The indications and the detailed technique of extravesical antirefluxplasty are presented. Realized on 409 ureters (247 cases), extravesical antirefluxplasty has been successful in 95% of these cases. The failures, i.e., obstructions (1,5%) and persistent reflux (3%), are analized.

Humans

[Late urological complications of reconstructive surgery of the aortic bifurcation (author's transl)].

Ureteral obstruction following aorto-iliac or aorto-femoral dacron prosthesis has rarely been described. It seems, however, as shown in our three cases, that this complication is more common than was previously believed. In all three cases, ureteral obstruction was attributed to retroperitoneal fibrosis enclosing the graft. The threat of such a complication should lead the surgeon to carry out intravenous urography in all patients with a vascular prosthesis.

Aged

[The physiopathology of vesicoureteral reflux (author's transl)].

The tightness of the ureterovesical junction depends on all the structures composing the terminal and intra-mural ureter. The muscular, collagenic, and elastic fibers of the ureter constitute a mesh net which is stretched during bladder distention and closes the ureteric orifice as a valve. Congenital vesico-ureteric reflux results from a primary structural insufficiency of the terminal ureter or insufficiency of the bladder wall backing. As embryology shows primary reflux can be caused by a high ectopic implantation of the ureter. It results from the development of an ureteric bud appearing in a lower than normal position on the Wolffian duct. This results in a higher and more lateral opening of the ureteric orifice in the bladder which leads to a shorter intra-mural tunnel predisposing it to reflux. Secondary or acquired refluxes are associated with chronic obstructions (i.e. neurogenic bladder--lower urinary tract obstruction), and inflammatory lesions. Their pathogeneses are described and discussed. The maturation of the ureterovesical junction is considered a mechanism involving a reduced likelihood of secondary reflux. It may also, during the first years of life, palliate some minimal structural deficiencies of the intra-mural ureter, but growth and development are unlikely to normalize an ureter presenting at birth with a severe constitutional anomaly.

Adolescent