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Biomedical subjects

W G Webster

Publications and source records attributed to W G Webster.

29 records · Page 2Linked to original sources

Morphological asymmetries of the cat brain.

The fissure patterns of 112 cat brains were examined and 45% were found to be asymmetric with respect to Otsuka and Hassler sulcus pattern types. As well, 22% were asymmetric with respect to the presence of a postcrutiate sulcus. No relationship was found between the presence or asymmetry of specific cortical features and paw preference, suggesting that these asymmetries are not associated with a functional asymmetry in visual discrimination performance previously demonstrated in the cat.

Animals↗

Problem-solving strategies and manifest brain asymmetry.

The dichhaptic stimulation procedures developed by Witelson (1974) for the study of brain lateralization in children were modified and extended for use with adults. Consistent with findings in children, an overall left hand advantage was found under conditions of simultaneous or dichhaptic stimulation, although it was not found under conditions of monohaptic stimulation. The major purpose of the study was to determine whether in adults hand differences (assumed to reflect hemisphere utilization) could be influenced by the use of differential problem-solving strategies. Half the Ss were instructed to approach the haptic learning and recognition problems in a "sequential" or "analytic" manner, and half to approach them in a "holistic" or "Gestalt" manner. The results indicated that the degree of left hand superiority was indeed influenced by this manipulation, although it is to be noted that the actual basis of the effect is unclear. The results were consistent with the idea that brain lateralization must be defined, not strictly by tasks, but by strategies used by subjects to perform the tasks used to detect and study that lateralization. It is suggested that this immensely complicates the issue of interpreting the origin and basis of individual and group differences in laterality effects.

Adult↗

Anatomical asymmetry of the cerebral hemispheres of the cat brain.

The fissure patterns of 39 cat brains were examined and each hemisphere was classified according to the scheme of Otsuka and Hassier. Of the 33 brains for which there was no ambiguity of classification for either hemisphere, 45 percent were asymmetrical. Included among these asymmetrical brains was that of a newborn kitten. As the asymmetry is focussed predominantly in the region of the visual cortex, it is suggested that this may form the substrate of the functional asymmetry in visual discrimination performance previously demonstrated in cats.

Animals↗

Interocular transfer of lateral mirror-image discriminations by cats: evidence of species differences.

Interocular transfer of mirror-image discriminations has been shown to be paradoxical in split-chiasm monkeys tested in a lighted Wisconsin General Test Apparatus (WGTA) with 3-dimensional forms, but veridical in split-chiasm cats tested in a darkened 2-choice discrimination box with transilluminated patterns. In the present study, 8 split-chiasm cats showed veridical interocular transfer of a mirror-image and a non-mirror-image discrimination in a WGTA or a 2-choice discrimination box. On the basis of the testing parameters used, it is argued that the discrepancy in the literature arises from a species difference (having a behavioral rather than a gross neurological basis), and not from differences in behavioral testing apparatus or mode of stimulus presentation.

Animals↗

Development of paw preference in rats following unilateral cortical ablations in infancy.

Rats which received unilateral anterior cortical lesions in infancy manifested a preference for the paw contralateral to the intact hemisphere when tested at 5 wk. and at 10 wk. of age. That this effect was locus specific and was not due to a change in the over-all balance of activity between the hemispheres was indicated by the fact that similar lesions made in the posterior cortex did not influence which paw the animals subsequently preferred. The posterior lesions, however, may have lowered the frequency of ambidexterity, a finding interpreted in terms of theoretical arguments concerning bilateral symmetry and the discrimination and memory of left and right.

Age Factors↗