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Biomedical subjects

W Fleischmann

Publications and source records attributed to W Fleischmann.

46 records · Page 3Linked to original sources
PubMed1991

[Trends in indications and technique of osteosynthesis. Innovations in surgery of the spine].

More understanding of the biomechanics of injured segments, standardized dorsal and ventral accesses to all spinal column levels, and developments in fixation systems specifically conceived for the stabilization of vertebral column lesions have all greatly expanded the operative indications for spinal column injuries. Modern fixation systems should have the following features: short-term application, angular stability, universal suitability for all types of fractures, ability to bear axial loads, thus dispensing with the need for additional external stabilization.

Fracture Fixation↗
PubMed1991

The transfixational plaster cast technique.

Unstable fractures of the forearm and leg as well as combined fractures of the arm and forearm are often difficult to treat adequately by closed reduction and plaster fixation. In tropical countries, however, open reduction is relatively contra-indicated because of increased risk of peri-operative infection, inadequate training of medical personnel, and lack of adequate equipment. Given these conditions, the use of the transfixational plaster cast offers an alternative which is simple, inexpensive, and with few complications. The principle and technique of the transfixational plaster cast are presented.

Bone Wires↗
PubMed1991

[The treatment of distal upper arm fractures].

The treatment of fractures of the distal humerus is very well standardized. The classification according to Müller allows for easy differentiation between the many types of fractures, helps in the determination of therapeutic guidelines and contributes to an objective comparison of results of treatment. Fractures in group A/B are treated either conservatively or with comparatively simple instrumentation using K-wires, screws, and plates. Injuries falling in group C demand a high standard of operative skill. The underlying principle of internal fixation aims primarily at reconstruction of the articular surface. The next operative step consists in the realignment of the reconstructed articular block with the proximal humeral fragment by osteosynthesis. Autologous cancellous bone is used to give a solid counterbalance for screw fixation and to re-establish osseous continuity. Sound assessment of concomitant injury to the soft tissue demands wide clinical experience. This is necessary for essential decision as to whether primary osteosynthesis, delayed, secondary reconstruction of the joint following recovery of the soft tissue or conservative treatment is indicated.

Elbow Joint↗
PubMed1985

[Ischemic colitis following reconstructive interventions of the aortoiliac vascular segment].

Ischemic colitis after aortoiliac vascular reconstructions represents a seldom but life-threatening postoperative complication (incidence: 1.6%, mortality rate: 50-70%). The authors present a retrospective evaluation of 10 cases observed in a consecutive series of 1121 reconstructive aorto-iliac procedures. The incidence of ischemic bowel complications was 1.3% in the group of abdominal aortic aneurysms but only 0.6% in the group of arterial occlusive disease. The pathogenesis including new approaches of prophylaxis, diagnostic and therapeutical measures are discussed. The risk of ischemic damage to the bowel may be best assessed from the preoperative aortogram (special vascular patterns), the intraoperative stump-pressure measurement in the inferior-mesenteric artery and the pre- and postoperative PB-Index. In contrast to earlier reports the leading clinical symptom is an unexplained prolonged gastrointestinal paralysis during the first postoperative week. Early diagnosis is most important and best realized by the routine use of colonscopy in all risk cases in the first 48 h. Such an aggressive diagnostic approach offers the possibility of early relaparotomy in a pretoxic stage and a better outcome for the patient than heretofore with a median delay of 11 days between vascular reconstruction and relaparotomy.

Aged↗
PubMedDate not supplied

[InterPro as a new tool for whole genome analysis. A comparative analysis of Mycobacterium tuberculosis, Bacillus subtilis and Escherichia coli as a case study].

InterPro was developed as a new integrated documentation resource for protein families, domains and functional sites to rationalize the complementary efforts of the PROSITE, PRINTS, Pfam and ProDom database projects and has applications in computational functional classification of newly determined sequences lacking biochemical characterization and in comparative genome analysis. InterPro contains over 3500 entries, with more than 1000000 hits in SWISS-PROT and TrEMBL. The database is accessible for text- and sequence-based searches at http://www.ebi.ac.uk/interpro/. InterPro was used for whole proteome analysis of the pathogenic microorganism, Mycobacterium tuberculosis, and comparison with the predicted protein coding sequences of the complete genomes of Bacillus subtilis and Escherichia coli. 64.8% of the M. tuberculosis proteins in the proteome matched InterPro entries, and these could be classified according to function. The comparison with B. subtilis and E. coli provided information on the most common protein families and domains, and the most highly represented families in each organism. InterPro thus provides a useful tool for global views of whole proteomes and their compositions.

Bacillus subtilis↗