Search PubMed⌕ Search

Biomedical subjects

W F Tsoi

Publications and source records attributed to W F Tsoi.

At least 37 records · Page 2Linked to original sources

New admissions to a psychiatric ward in a general hospital.

A study of 343 new patients in the first psychiatric department in a general hospital in Singapore revealed a large proportion (40%, n = 137) of neurotic patients, especially neurotic depressives (n = 76). The next largest group is the non-organic psychoses 35% (n = 120), most of which were schizophrenic psychoses (n = 73). The other major diagnostic groups were adjustment or acute stress reactions, alcohol or drug dependence and personality disorders. The neurotic patients were generally older than the psychotic patients at the time of admission (p less than 0.02). More of them were married (62.7%) compared with the psychotics of whom 51.5% remained unmarried (p less than 0.02). Comparison between neurotic depressives and manic-depressive psychotics should have no difference in sex ratio and marital status. However, the duration of admission for the latter was longer.

Adolescent↗

Developmental profile of 200 male and 100 female transsexuals in Singapore.

Two hundred male and 100 female transsexuals compared with 100 male and 80 female heterosexuals were studied in Singapore. Transsexuals started their psychosexual development earlier than controls. Transsexual feelings started in childhood. Male transsexuals went through a homosexual phase followed by a transvestite phase, before they became transsexual. Female transsexuals did not go through distinct phases. Cross-dressing was one of the early signs of transsexualism and started earlier in females. None of the transsexuals were married, in contrast to reports showing that up to 50% of Caucasian transsexuals had been married. Cultural differences may explain the contrasts between Singapore transsexuals and patients from Western countries.

Adolescent↗

Serum protein markers in Chinese schizophrenics--haptoglobin types and transferrin and group-specific component subtypes.

Four hundred and thirty-nine Chinese schizophrenic male patients were investigated for the distribution of haptoglobin types; transferrin and group-specific component subtypes. The allelic frequencies of these three polymorphisms in the patient group were compared with those in healthy controls from published series. An excess of Gc2 over Gc1 (chi 2(1) 4.1; P less than 0.05) as well as a lack of Gc1S (chi 2(1) 15.3; P less than 0.001) was observed in schizophrenia. The relative risks of Gc1F, Gc1S and Gc2 have been estimated as 1.12, 0.76 and 1.15, respectively. It appears from this study that the presence of Gc2 renders individuals susceptible while Gc1S offers protection for schizophrenia. No such association was found for the haptoglobin or transferrin polymorphisms.

Blood Proteins↗

Parental influence in transsexualism.

This is a study of parental influence in a group of Chinese male and female transsexuals compared with a group of male and female heterosexual controls. There was no difference in the parental ages of the transsexuals and controls at time of their birth. The fathers of the male transsexuals and the mothers of female transsexuals were less involved in their upbringing. Using a bonding instrument, the fathers of male transsexuals were found to be less caring, and mothers of female transsexuals were less overprotective than the fathers and mothers of the controls. Studies on parental involvement in male transsexuals showed a weak father figure and an overinvolvement with the mother, and in female transsexuals, an unsatisfactory mother-daughter relationship. Abnormal parental-child relationship, postulated as an important aetiological factor in transsexualism, needs to be further confirmed.

Adult↗

Tardive dyskinesia.

Explore the source record for details and available documents.

Antipsychotic Agents↗

The prevalence of transsexualism in Singapore.

The prevalence of transsexualism in Singapore was estimated by counting all the patients who sought sex-reassignment surgery and were subsequently diagnosed as transsexuals by psychiatrists. Up to 1986, there were a total of 458 Singapore-born transsexuals, of which 343 were males and 115 were females. This was a prevalence of 35.2 per 100,000 population age 15 and above (or 1/2900) for male transsexualism, and 12.0 per 100,000 (or 1/8300) for female transsexualism. The sex ratio was about 3 males to 1 female. The main reason for the high prevalence was the availability of sex-reassignment surgery.

Adolescent↗

Suicide following parasuicide in Singapore.

Suicide was attempted by 1641 people (502 males and 1139 females) in Singapore during 1980. Eleven of these committed suicide during the following three years, giving a suicide rate of 0.67%. Of the eleven suicides, five had schizophrenia and three depression. The risk of suicide in the year following attempted suicide is lower in Singapore (0.5%) than in Britain (1.6%). High risk factors for the Singapore patients were being Chinese, being male, and having a mental illness.

Adolescent↗

Psychosocial characteristics of repeat aborters in Singapore.

"The psychosocial characteristics of 200 repeat aborters and 200 first time aborters [among] Singapore Chinese were compared with 200 antenatal patients. The repeat aborters started their sexual activities at an earlier age. They were married for a longer period, had more past pregnencies and more children, but their marital adjustments were slightly less satisfactory. There were no differences in education, housing, and religious practices among the three groups. The aborters knew more methods of contraceptive practices, but they tended to use unreliable methods. Their main reasons for seeking abortion were that their families were complete or that they wished to space births."

Abortion Applicants↗