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Biomedical subjects

W F O'Dwyer

Publications and source records attributed to W F O'Dwyer.

At least 19 recordsLinked to original sources

Aluminium encephalopathy: clinical and immunological features.

Aluminium encephalopathy is a specific syndrome occurring in dialysis patients and linked to high aluminium levels in dialysis water. We present the features of 38 cases seen in a single dialysis and transplantation unit. Serum immunoglobulin levels and the prevalence of histocompatibility antigens are discussed. The syndrome in its complete form is specific and easily recognizable. Careful attention to premonitory symptoms may lead to earlier diagnosis.

Aluminum↗

HLA-A, -B and -DR antigens in IgA nephropathy.

Fifty-six Irish patients with IgA Nephropathy were typed for HLA-A and -B antigens. Forty-six were typed for HLA-DR antigens. The frequencies of these antigens did not differ significantly from the frequency in the general population. The influence of genetic factors in the pathogenesis of this disease remains uncertain.

HLA Antigens↗

Nephrotic syndrome in Hodgkins disease.

A case of nephrotic syndrome due to minimal lesion glomerulonephritis associated with Hodgkins disease is described. The course of the nephrotic syndrome was relapsing, preceeding the development of lymphoma by eighteen months. Treatment of this nephrotic syndrome with repeated courses of Prednisone and Cyclophosphamide resulted only in partial improvement of his proteinuria. However, complete absence of proteinuria only occurred with successful therapy of Hodgkins disease.

Child↗