Biomedical subjects

W F Lever

Publications and source records attributed to W F Lever.

At least 37 records · Page 2Linked to original sources

PubMed1977

Localized mycosis fungoides with prominent epidermotropism: Woringer-Kolopp disease.

A patient had a single, large, sharply demarcated lesion on one leg. Under the mistaken diagnosis of malignant melanoma in situ, the lesion was excised and the area grafted in 1956. There has been no recurrence in the past 20 years. Histologic reevaluation led to a diagnosis of mycosis fungoides with pronounced epidermotropism of the cellular infiltrate. This case has close clinical and histologic resemblance with three cases published in Europe and regarded as a special form of reticulosis as first described by Woringer and Kolopp. Mycosis fungoides with marked epidermotropism is not always a benign localized disease but may be widespread and lead to death.

Adult↗

PubMed1975

Secretion from human apocrine glands: an electron microscopic study.

Electron microscopic examination of apocrine glands revealed three types of secretion: merocrine apocrine, and possible holocrine. In the merocrine type of secretion numerous vesicles originating in the Golgi area discharged their granular contents into the lumen of the gland. In the apocrine type of secretion three stages were observed: (1) formation of an apical cap; (2) formation of a dividing membrane at the base of the apical cap; and (3) formation of tubules avove the dividing membrand that extended parallel to the membrane and led to a separation of the apical cap from the underlying cell, In the holocrine type of secretion individual secretory cells or even strands of secretory cells were dischard into the lumen of the gland.

Adult↗

PubMed1975

Ultrastructural localization of in vivo bound immunoglobulins in bullous pemphigoid--a preliminary report.

The ultrastructural location of in vivo bound immunoglobulins in a case of bullous pemphigoid was determined by coupling peroxidase to antihuman gamma globulin. Immunoglobulin deposits were found exclusively in the space between the basal cells and the basal lamina. The location of the immunoglobulin in bullous pemphigoid thus differs from that in lupus erythematosus where immunoglobulins are found mainly below the basal lamina.

Antibodies, Anti-Idiotypic↗

PubMed1974