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Biomedical subjects

W F Collins

Publications and source records attributed to W F Collins.

69 records · Page 4Linked to original sources

Evaluation of the neurotoxicity of water-soluble myelographic contrast agents by electrophysiological monitors.

The effects of subarachnoid injection of Conray (methylglucamine iothalamate) and its dimer (methylglucamine locarmate) in various concentrations were compared using electrophysiological monitors of the cortical evoked response (CER) and the H-reflex. Significant concentration-dependent differences were noted in the H-reflex, less marked with the dimer. No significant difference in the CER was noted. This differential alteration in neurophysiological parameters was independent of changes in blood and cerebrospinal fluid pressure, implying that these water-soluble contrast media have a direct toxic effect on the nervous system, possibly situated in the larger (group 1) root fibers.

Animals↗

Bifrontal decompressive craniectomy in the management of head trauma.

Retrospective analysis of 13 patients who had bifrontal decompressive craniectomy for the management of posttraumatic cerebral edema shows a significant decrease in expected mortality, but severe morbidity in the survivors. Only one patient returned to the pretrauma level of neurological function. No correlation could be found between the quality of survival and the neurological or operative findings. The need for more accurate prognostic criteria in the evaluation of severely head-injured patients is discussed.

Adolescent↗

Femoral nerve injury following inguinal hernia repair.

Insidious leg pain and weakness followed inguinal hernia repair. Despite the temporal relationship of the surgery and the symptoms, the diagnosis proved elusive, in part, because of the rarity of the complication.

Child↗