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Biomedical subjects

W F Beyer

Publications and source records attributed to W F Beyer.

53 records · Page 3Linked to original sources
PubMedDate not supplied

[Solitary infantile myofibromatosis of the sacrum].

The infantile myofibromatosis is the most common fibrous tumor of infancy. One may find solitary lesions of dermal, visceral, musculoskeletal and subcutaneous tissues. Multiple lesions without visceral involvement generally take a benign course. Because the lesion is commonly known only to pathologists, infantile myofibromatosis is often misdiagnosed and underreported. Therefore we present a review of the pathology and symptoms of infantile myofibromatosis together with a case report of a solitary lesion of bone.

Adolescent↗
PubMedDate not supplied

[Comparative histomorphometry of subchondral bone density and articular cartilage thickness in the tibial head in early human arthritis].

The articular cartilage thickness and subchondral bone density of 50 human tibial heads were histomorphometrically measured by an image analysing system and topographically examined in relation to age, sex and grade of osteoarthrosis (OA). Altogether we evaluated 12,000 items. Independent of OA the lateral tibial plateau shows a significant thicker cartilage layer than the medial. In central joint areas we find a thicker cartilage cover than in marginal. Corresponding to the literature cartilage fibrillation according to OA grade 1 and 2 (Otte 1969, Fassbender 1975) accumulates in the lateral and dorsal tibial head including the meniscus covered area. The cartilage thickness decreases with age independent of OA. Without major alterations of the topographical pattern the cartilage thickness however shows a significant increase in early OA (grade 1). For that reason measurements of the cartilage thickness and joint space narrowing are not appropriate for defining early OA. The subchondral bone density shows high values ventromedially and dorsolaterally independent of sex, age or OA. Beneath central joint areas higher values are found than marginally. Corresponding to the topical literature our results point at the model of the real loaded knee joint, which says that the mean loading forces do not act on the middle of the joint but on the medial plateau. The dorsolateral density centre could be an expression of the functional adaptation of the bended knee joint. In joint areas with cartilage fibrillation (OA grade 1) we find a significant higher subchondral bone density without major alterations of the topographical pattern. It is not possible to define cause and effect, we interpret both as result of higher joint loading.

Adolescent↗
PubMedDate not supplied

[Roentgen morphologic study of arthrosis of the sternoclavicular joint].

X-rays of 102 sternoclavicular joints from post-mortem examination were interpreted systematically. In 89 cases we found an osteoarthrosis. We investigated the correlation between stage of osteoarthrosis and size and form of articular surface, age, sex and right or left preference. We also made a review about anatomy, embryology and pathology of the sternoclavicular joint. The differential diagnosis of sternoclavicular pain is discussed.

Adult↗
PubMedDate not supplied

[The styloid syndrome. Differential diagnosis of degenerative diseases of the cervical vertebrae--case report with literature review].

Elongated Styloid Process Syndrome requires its consideration in differential diagnosis of degenerative disease of the cervical spine. Radiating pain on certain movements of the cervical spine is a symptom of an elongated styloid process as well. First basic anatomy and pathology, symptoms and differential diagnosis of the elongated styloid syndrome are discussed. A case history is presented together with X-rays of the cervical spine and images of three dimensional CT-reconstruction to show the full length of an elongated styloid process.

Adult↗
PubMedDate not supplied

[Osteomyelitis following BCG vaccination].

Typical for the case history of a patient with the very rare vaccination-induced osteomyelitis is a relatively long interval between the BCG-vaccination and the initial clinical symptoms. The course of the disease is undramatic. Pronounced changes are frequently visible in x-rays and, with proper surgical and tuberculostatic therapy, the prognosis is good as well. The morphological changes in cases of BCG-osteomyelitis cannot be distinguished from those caused by tuberculosis. The same causal factors as for other possible BCG-complications are considered pathogenically significant for its development, perhaps as a result of a local trauma, too. When a BCG-osteomyelitis is suspected clinically, a curettage of the affected bone tissue is indicated for diagnostic as well as therapeutic purposes. A cause of BCG-osteomyelitis, diagnosed in a three-year-old girl, was described causally in detail.

Antitubercular Agents↗
PubMedDate not supplied

[The significance of inflammatory changes in the tarsometatarsal joints for development of rheumatic splayed foot: a radiologic follow-up].

The involvement of foot joints is a common finding in more than 90% of the patients with rheumatoid arthritis. The typical deformity of the forefoot is the splayfoot with hallux valgus or hallux rigidus and deformities of the lesser toes. 70 feet of 36 patients with rheumatoid arthritis were observed radiologically over a period between 5 years/1 month and 6 years/1 month. The x-rays were analyzed for arthritic changes of the various joints and changes of the foot statics. The question was whether the splay of the forefoot is caused by an arthritis of the metatarsophalangeal or tarsometatarsal joints with a consequent weakening of joint capsules and ligaments, or statistically by a flattening of the longitudinal arch owing to arthritic changes of the hindfoot. The statistic analysis showed that the splay of the forefoot appears between the first and second metatarsal bones. The arthritis of the tarsometatarsal joints II-IV could be identified as a statistically significant factor for the development of a splayfoot in rheumatoid arthritis. The influence of arthritic changes of the tarsometatarsal joints I and V was striking, but not statistically significant. The arthritis of the tarsometatarsal joints caused a flattening of the transverse arch already at an early stage. An arthritis of the metatarsophalangeal joints and the flattening of the longitudinal arch with arthritides of the rear foot had no statistically significant influence on the forefoot. From the results, we must draw the conclusions that orthopedic aids like shoe supports with retrocapital metatarsal bars should be recommended already at an early stage of the disease and that the support of the longitudinal arch is not sufficient to prevent a splayfoot.

Adult↗