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Biomedical subjects

W Eicher

Publications and source records attributed to W Eicher.

At least 37 records · Page 2Linked to original sources
PubMed1980

[Transexuality and X-Y antigen (author's transl)].

Eleven transexuals with transexuality from man to woman and a karotype 46 X-Y and 11 transexuals with transexuality from woman to man and the karotype 46 X-X were investigated for H-Y antigen. Eight of the 46 X-Y transexuals were H-Y antigen negative, one intermediately slightly positive and two H-Y antigen positive. Of the 46 X-X transexuals 9 were H-Y antigen positive, one was intermediately slightly positive and one was H-Y antigen negative. Two groups of transexuals can be distinguished. Genuine transexuals and secondary transexuals with a transvestite past who have suffered a sexual identity crisis due to the environment. The H-Y antigen is an expression of a complex of the genes which is responsible for virilization and is likely located in the Y chromosone. The gene responsible for the H-Y antigen expression is not identical with the inductor for testicular development. An explanation for the disordance of the H-Y antigen findings in transexuals is translocation or gene exchange from a Y-chromosome to an X-chromosome during meisis of the spermatogonia. In this way a morphological substrate for transexuality has been detected. H-Y antigen negative 46 X-Y males and H-Y antigen positive 46 X-X females can now be diagnosed as genuine morphological transexuals.

Environment↗
PubMed1979

[The epidemiology of breast neoplasms].

In an epidemiologic study the risks of breast cancer were assessed. An evaluation of the distribution of different tumor stages revealed that more information, in a larger sense more civilization, workship and the life in town makes women more curious and brings them to go sooner to the doctor. A lack of information correlates with more advanced stage of tumor. Significantly more childless women suffer of breast cancer, but a high number of children is no protection. In women with 3 and more children yet more advanced stages were seen. This may be interpreted by isolation, lack of information and distress. A significantly high number of breast cancer patients lost one of their parents by death before the age of 20, which confirms the psychosomatic theory of cancerogenesis (overcoming of the "Objektverlust" in early childhood). The incidence of depressive states before the onset of the disease is significantly higher. A reduced capacity to communicate was also observed. The exploration of sexual behaviour showed more frequently a reduced sexual activity correlated to cohabitarche, number of partners, alibidimia, unwanted pregnancy and masturbation. The ability of adequate sexual life was deeply disturbed by disease and therapy. Following primary therapy intelligent guidance of the patient may avoid occurrence of disturbances of sexual communication.

Breast Neoplasms↗
PubMed1976

[Disorders of libido from the gynecological view point].

Sexual dysfunctions are differentiated according to the following symptoms: libido dysfunction, orgasmic dysfunction, vaginism, algopareunia and polysymptomatic dysfunction. In the out-patient service for sexual and other psychosomatic disorders of the University of Heidelberg's Women's Hospital 90 women with libido dysfunction were treated with conflict-centered psychotherapy after exclusion of organic diseases which could explain the reduction of libido and after exclusion of a depression where the loss of libido is a regular symptom. The success-rate was 63%. It was attempted to reinforce the ego of the patient which enables him to experience his surroundings with less conflicts. Neurotic anxieties and symptoms are decreased and loos their importance so that the patient is able to handle his sexual disturbance. Among the psychosocial factors, i.e. focal causes, responsible for the libido dysfunction we found: In 48% of the cases the relationship between parents and children had been disturbed, which caused difficulties in the identification process (lack of father or mother, cool mother, divorce, borken home). Problems with the partners were found in 42%. 2/3 of these women had not grown up in intact families, which seems to predestinate difficulties in communication later on. Psychodynamically the loss of libido means sexual resistance which can lead to aversion or disgust. When there is no excitement the vasocongestion and lubrication do not take place: cohabitation pain (algopareunia) results. On the other hand the reduction of libido can also be a result of chronic algopareunia, i.e. secondary. Psychogenic bleedings ("aversion-bleeding") during or after intercourse occasionally occur in combination with algopareunia and lack of libido.

Dyspareunia↗
PubMed1975

[Organic changes and pain after laparoscopic tubal sterilization].

In 100 women who underwent laparoscopic sterilization approximately one year before a follow-up check including gynecological examination, a structurized interview and a "Maudsley Personality Inventory" (MPI) test were performed. 6% complained about algopareunia before the operation which did not disappear afterwards. In 8 patients algopareunia started after the operation, only 2 of them presenting pelvic adhesions at control, whereas 6 patients suffered from psychogenic algopareunia. Neurotic tendency was evidently elevated in all those patients complaining about pelvic pain before and after operation. 6 patients had pelvipathia nervosa, 14 showed organic alterations, but these were not necessarily the reason for the complaints. Laparoscopy revealed pathologic processes e.g. adhesions, pelvic varicosis or adnexitis in 27%, but not more than 11% of these patients with obvious pathology had subjective complaints. These findings underline the fact that pathologic alterations will not necessarily explain pelvic pains and that in most cases psychosomatic factors must be taken into consideration.

Dyspareunia↗