Some effects of pentamidine di-isethionate on Crithidia fasciculata.
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Adenine↗
Biomedical subjects
W E Gutteridge
Publications and source records attributed to W E Gutteridge.
Growth of Trypanosoma cruzi in human heart tissue cells and effects of aminonucleoside of puromycin, trypacidin and aminopterin.
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Amino Acids↗
Presence and properties of dihydrofolate reductases within the genus Trypanosoma.
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Aminopterin↗
566C80, an antimalarial hydroxynaphthoquinone with broad spectrum: experimental activity against opportunistic parasitic infections of AIDS patients.
Hydroxynaphthoquinone 566C80 was synthesised and initially developed as an antimalarial with potent activity against drug-resistant strains of the human malaria parasite, Plasmodium falciparum. Subsequent studies have revealed that in addition, this compound has experimental activity, both in vitro and in vivo, against Pneumocystis carinii and Toxoplasma gondii; the data obtained thus far for Cryptosporidium parvum are equivocal. Currently 566C80 is being assessed clinically not only against malaria, but also against P. carinii pneumonia, toxoplasmosis and cryptosporidiosis.
Acquired Immunodeficiency Syndrome↗