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Biomedical subjects

W E Benson

Publications and source records attributed to W E Benson.

At least 73 records · Page 4Linked to original sources

Intraocular irrigating solutions for pars plana vitrectomy. A prospective, randomized, double-blind study.

A prospective, randomized, double-blind study showed that glutathione-bicarbonate-Ringer's solution (BSS Plus) caused significantly less corneal swelling on the first postoperative day after pars plana vitrectomy than did lactated Ringer's solution. By the seventh postoperative day, no difference was seen between the two solutions. We found no correlation between the increase in corneal thickness and either the duration of intraocular irrigation or the volume of solution used or the presence or absence of the lens. No persistent corneal complications were seen.

Adolescent↗

The effects of panretinal photocoagulation on dark adaptation in diabetics with proliferative retinopathy.

The dark adaptation of 14 diabetic patients was measured before and after panretinal photocoagulation (PRP). The rod-cone break of diabetics prior to PRP was delayed 1.7 minutes compared to normal controls and the final rod threshold was elevated 0.7 log units. After PRP, the rod-cone break was delayed 2.9 minutes and the final rod threshold was elevated 1.1 log units.

Dark Adaptation↗

Preparation of intravitreal drug doses.

Due to the narrow therapeutic index injected into the vitreous cavity, this study was undertaken to determine the accuracy of preparation of an intravitreal drug dose (400 microgram/0.1 ml from a stock solution of 40mg/ml) when prepared by pharmacists and physicians using the preparation method each would utilize in a clinical setting and to determine which of nine standard preparation methods is most accurate.

Humans↗

Subretinal neovascularization in chronic uveitis.

This paper describes two young patients who developed subretinal neovascularization (SRNV) of choroidal origin as a complication of chronic uveitis of undetermined etiology. The probable mechanism of SRNV development and the differential diagnosis of the intraocular inflammatory condition are presented.

Adolescent↗

Reversible night blindness associated with intestinal bypass surgery.

A 33-year-old man had a sudden onset of night blindness 3 1/2 years after intestinal bypass surgery for morbid obesity. Ocular examination disclosed a probable Bitot's spot and electrophysiologic testing showed markedly impaired dark adaptation and subnormal electroretinography. After therapy with orally administered vitamin A, the night blindness disappeared and the dark adaptation curve and electroretinogram returned to normal.

Adult↗

Ocular toxoplasmosis and visual field defects.

We studied 34 patients with peripapillary lesions secondary to toxoplasmosis. All patients had visual field defects corresponding to interruption of the nerve fiber layer of the retina. The extent of visual field loss increased with proximity to the disk.

Adult↗

Computed tomographic localization of the precentral gyrus.

The superior frontal, precentral, and central sulci of fixed brain specimens were marked and then scanned by computed tomography. A constant relationship between the posterior ends of the superior frontal and precentral sulci facilitated accurate identification of the anterior border of the precentral gyrus in both unmarked fixed brains and patients. Precise localization of this gyrus can aid in localization of lesions and correlation with functional changes.

Humans↗

Posterior scleritis. A cause of diagnostic confusion.

The referring diagnoses in seven women with posterior scleritis included intraocular neoplasm, retrobulbar tumor, choroiditis, and idiopathic central serous choroidopathy. In all cases, a localized area of intense posterior scleritis was responsible for the misdiagnosed ocular findings. Features that helped to correctly identify posterior scleritis were as follows: female sex; a history of anterior scleritis; a fundus mass the same color as normal adjacent pigment epithelium; choroidal folds; serous retinal detachment with cloudy fluid; early pinpoint leaking spots from fluorescein angiography; and thickening of the posterior coats of the eye, retrobulbar edema, and high internal reflectivity on ultrasonography. Corticosteroids given for retrobulbar or systemic effect provided effective treatment.

Adult↗

Cystoid macular edema after cryotherapy.

A 50-year-old man developed cystoid macular edema five weeks after cryotherapy of acute retinal tears. The cystoid edema cleared spontaneously, but ultimately the fovea developed wrinkling of the internal limiting membrane.

Cryosurgery↗

Presumed spontaneously regressed retinoblastoma.

A history of blindness in one eye since childhood, the fundus appearance of the other eye, and the family history of elevated plasma levels of carcinoembryonic (CEA) antigen and colorectal carcinoma led us to diagnose bilateral spontaneously regressed retinoblastoma. Massive gliosis of the retina was found in the eye enucleated because of blindness and pain. The diagnosis of regressed retinoblastoma should be considered where the pathologic diagnosis of an enucleated eye is massive gliosis of the retina, but where no known cause is present.

Adult↗

Late hyphema due to vascularization of the cataract wound.

Nineteen patients with hyphema due to fibrovascular tissue in the cataract wound were seen. In 3 patients the hyphema occurred after closure of an unitentional filtering bleb. Two patients receiving anticoagulants before and after the hyphema occurred did not have recurrence of the bleeding. In one patient the hyphema was induced by scleral depression. This benign condition is frequently misdiagnosed. When erythrocytes are seen in the anterior chamber of an aphakic patient, vascularization of the cataract wound should be suspected and confirmed by gonioscopy.

Adult↗

The prognosis of retinal detachment due to lattice degeneration.

In a series of 553 consecutive retinal detachments, 29% (120) were due to lattice degeneration. Forty-five percent of these were due to atrophic holes in the lattice degeneration and 55% were due to tears caused by traction posterior to or at the end of a patch of lattice. In phakic patients, retinal detachments due to atrophic holes were most common in young myopes. Detachments due to traction tears were seen in older, less myopic patients. The incidence of massive periretinal proliferation was less (5%) in detachments due to lattice degeneration than in detachments not due to lattice degeneration (6.5%).

Adolescent↗

Hemorrhage from isolated aneurysm of a retinal artery: report of two cases simulating malignant melanoma.

Isolated retinal arterial aneurysms or macroaneurysms of the retinal arteries may be the cause of hemorrhage in the retina or vitreous. Two cases are reported in which hemorrhages from isolated retinal arterial aneurysms clinically simulated malignant melanoma of the choroid. Previous studies of lesions simulating malignant melanoma of the uvea have shown that vitreous and retinal hemorrhage may easily mislead the clinician. It is stressed that careful prolonged observation does not materially decrease the patient's chance for survival if he does have a malignant melanoma and may prevent an unnecessary enucleation.

Aged↗

Late complications following cryotherapy of lattice degeneration.

We observed 341 patients who had received cryotherapy for lattice degeneration in order to identify possible late complications. Sequelae such as retinal tears posterior to an operculum or flap tears within treated areas showed that treatment did not necessarily prevent subsequent vitreous traction. Moreover, the newly created flap tears may extend beyond the treated area and can cause retinal detachment. Even scleral buckling did not necesserily prevent further traction. Therefore, we concluded that when cryotherapy is used to treat lattice degeneration, an adequate margin of surrounding retina should be treated and the treatment should extend to the ora serrata.

Cryosurgery↗