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Biomedical subjects

W Duspiva

Publications and source records attributed to W Duspiva.

35 records · Page 2Linked to original sources

[New aspects of anastomoses of severed peripheral nerves].

Nerve anastomoses glued with Fibrinkleber are stabilized against the plasminogen-activators of the tissue by natural and synthetical inhibitors of fibrinolysis administered locally and systemically. So the early lysis of the clots is inhibited. The glued nerve anastomoses do not reach the bond strength of sutured nerves, but foreign body reactions are avoided by this method. Glueing nerves with Fibrinkleber combined with inhibition of fibrinolysis seems to be a good method reuniting severed nerves, especially in nerve transplantation, provided too much tension is avoided.

Antifibrinolytic Agents↗

[Experiences with replantation of large limbs].

From November 1975 to August 1978 26 limb replantations were performed. All 5 lower extremities had to be reamputated. Of the 21 replanted arms 15 healed without major complications, 9 have regained sufficient function up to now; 3 others show signs of reinnervation.

Accidents, Occupational↗

Early experiences in organising and running a replantation service.

In the 10 months since the establishment of a 24-hour replantation service, the centre at the Klinikum rechts der Isar of the Technical University of Munich has treated 162 amputation injuries; 132 underwent replantation surgery and 117 of these healed successfully. Surgical technique, medication and postoperative treatment with physiotherapy are described. Special emphasis is placed on the difficulties associated with crush and avulsion injuries; in most of them the only solution is an intermediate vein graft to bridge the defect in the vessels.

Amputation, Traumatic↗

[Covering defects by free grafting of skin and soft tissue with microvascular anastomoses (author's transl)].

The technique of free tissue transplantation with microvascular anastomoses in 3 patients is presented. Transplants consisting of skin and subcutaneous tissue from the groin with the superficial circumflex iliac artery and the superficial epigastric artery were used to cover defects over the calcaneum and to treat a scalping wound of the head, and a transplant from the dorsum of the foot with the A. dorsalis pedis and accompanying sensory nerves to the palmar surface of a hand following a third degree burn. Eight of a total of 13 transplants with microvascular connections healed completely. Partial necrosis occurred three times and total necrosis twice.

Adolescent↗

[Complications in free flap transfer with microvascular anastomosis].

We used free flap transfers with microvascular anastomoses to cover defects on head, leg, foot and hand. In our experiences of 12 cases we got 2 total and 3 partial necroses of the transplants. The possible causes of the failures are discussed, and the results are compared with other reports. The significance of the method in hand surgery is demonstrated, comparing groin and dorsalis pedis flaps.

Adolescent↗

[A new method of anastomosing severed nerves].

Nerve anastomoses glued with "Fribrinkleber" can be protected from tissue plasminogen-activators both by natural and synthetic inhibitors of fibrinolysis whether administered locally or systemically. The glued nerve-anastomoses do not attain the bond strength of sutured nerves, but show less foreign body reaction. Gluing nerves with Fibrinkleber" combined with inhibition of fibrinolysis would seem to be a good method for reuniting severed nerves. It may be especially useful in nerve transplantation if tension is avoided.

Animals↗

[Complications in the replantation of amputated digits].

The reason for thrombosis in replantation is very often the injured intima of the vessel ends. The vessel ends should be excised until absolutely normal tissue is reached. In many cases of oblique cutting, avulsion or crushing it is then difficult or impossible to approximate the ends and venous grafts are employed to avoid undue skeletal shortening.

Amputation, Traumatic↗

[Successful re-implantation of the metacarpus (author's transl)].

Two cases of subtotal traumatic metacarpal amputation in young people are described. Re-implantation with the help of microvascular surgical techniques was successful. In one case in which vascular connections to two long fingers were still present, the advantages of reconstruction of important vessels are pointed out, not only for re-implantation itself, but also as prophylaxis against circulatory disorders.

Adult↗