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Biomedical subjects

W Dunlop

Publications and source records attributed to W Dunlop.

82 records · Page 5Linked to original sources
PubMed1978

Clinical relevance of coagulation and renal changes in pre-eclampsia.

Changes in coagulation tests (fibrin/fibrinogen degradation products, factor-VIII activity, and platelet-count) and in renal function (creatinine clearance and serum concentration, clearance, and fractional reabsorption of urate) were measured in late pregnancy. 10 patients with severe preeclampsia showed changes in both coagulation and renal function when compared with 13 normotensive controls. 18 patients with mild pre-eclampsia had changes in renal function only. Results from 5 patients with essential hypertension did not differ from those of the normotensive group. When results from the patients with severe pre-eclampsia were arranged in order of decreasing protein excretion, only renal-function tests correlated significantly with this ranking. It is suggested that, in the management of patients with established preeclampsia, assessment of renal function may be of greater practical value than measurement of the degree of coagulopathy.

Adult↗
PubMed1978

Maternal haemoglobin concentration, haematocrit and renal handling of urate in pregnancies ending in the births of small-for-dates infants.

In nine patients who gave birth to babies below the fifth centile in weight, serum urate concentration and fractional reabsorption of urate were significantly higher than in 25 control patients whose babies were of normal birth weight. Haemoglobin concentration and haematocrit were also significantly increased in the small-for-dates group. All of these changes may reflect depletion of extracellular fluid volume.

Adult↗
PubMed1977

The effect of normal pregnancy upon the renal handling of uric acid.

Twenty-four women were investigated serially during and after normal pregnancy. Plasma uric acid concentration appeared to be inversely related to uric acid clearance under infusion conditions, and comparison with simultaneous inulin clearance suggested an alteration in renal function resulting in increased 'net tubular reabsorption' of uric acid as pregnancy progressed. No difference was detected between primigravidae and multigravidae. The implications of these changes are discussed with reference to the renal handling of uric in pre-eclampsia.

Adult↗
PubMed1977

Hemobilia associated with a traumatic arteriovenous fistula.

Although there have been many reports of hemobilia, its association with an arteriovenous fistula within the liver is extremely rare, only two cases having been reported in the world literature. The authors describe a third case in which a gunshot injury to the liver of a 19-year-old man resulted in the development of hemobilia demonstrated radiologically to be associated with an arteriovenous fistula. The condition was successfully managed by ligation of the proximal hepatic artery.

Adult↗
PubMed1976

Investigations into the influence of posture on renal plasma flow and glomerular filtration rate during late pregnancy.

Renal plasma flow and glomerular filtration rate were investigated in three positions (supine, left lateral and sitting) in a group of eighteen healthy women during late pregnancy and again after the puerperium. No difference in renal function could be attributed to the position adopted. However, an unexplained decrease in both of the indices occurred during the course of prolonged infusion in any position.

Adolescent↗