Experimentally induced degenerative joint lesions following partial meniscectomy in the rabbit.
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Animals↗
Biomedical subjects
W Davis
Publications and source records attributed to W Davis.
Immunoprofile studies for patients with bronchogenic carcinoma--III. Multivariate analysis of immune tests in correlation with survival.
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Blood Cell Count↗
Analysis of air contrast barium enema, computed tomographic colonography, and colonoscopy: prospective comparison.
BACKGROUND: The usefulness of currently available colon imaging tests, including air contrast barium enema (ACBE), computed tomographic colonography (CTC), and colonoscopy, to detect colon polyps and cancers is uncertain. We aimed to assess the sensitivity of these three imaging tests. METHODS: Patients with faecal occult blood, haematochezia, iron-deficiency anaemia, or a family history of colon cancer underwent three separate colon-imaging studies--ACBE, followed 7-14 days later by CTC and colonoscopy on the same day. The primary outcome was detection of colonic polyps and cancers. Outcomes were assessed by building an aggregate view of the colon, taking into account results of all three tests. FINDINGS: 614 patients completed all three imaging tests. When analysed on a per-patient basis, for lesions 10 mm or larger in size (n=63), the sensitivity of ACBE was 48% (95% CI 35-61), CTC 59% (46-71, p=0.1083 for CTC vs ACBE), and colonoscopy 98% (91-100, p<0.0001 for colonoscopy vs CTC). For lesions 6-9 mm in size (n=116), sensitivity was 35% for ACBE (27-45), 51% for CTC (41-60, p=0.0080 for CTC vs ACBE), and 99% for colonoscopy (95-100, p<0.0001 for colonoscopy vs CTC). For lesions of 10 mm or larger in size, the specificity was greater for colonoscopy (0.996) than for either ACBE (0.90) or CTC (0.96) and declined for ACBE and CTC when smaller lesions were considered. INTERPRETATION: Colonoscopy was more sensitive than other tests, as currently undertaken, for detection of colonic polyps and cancers. These data have important implications for diagnostic use of colon imaging tests.
Barium Sulfate↗
Alcoholism in Vietnam and Korea veterans: a long term follow-up.
The prevalence of alcoholism was assessed in veterans of the Vietnam and Korean wars. In addition, the role played by exposure to combat in excessive alcohol consumption was evaluated. One-third of patients attending clinics that were not devoted to the treatment of alcoholism had alcohol-related problems. This is far in excess of general population prevalence estimates. A significant association was found between combat exposure and excessive alcohol use. Close to 60% of a group of veterans exposed to combat drank excessively at the time of our study versus only 25% of a group of veterans of the Vietnam and Korean eras. An association between alcoholism and war experiences had already been observed by others in the early postwar era. Our data show that the effects of combat exposure can persist for more than a decade after the stressful events.
Alcoholism↗