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Biomedical subjects

W D Strohm

Publications and source records attributed to W D Strohm.

49 records · Page 3Linked to original sources
PubMed1978

[The diagnostic value of wedged hepatic vein pressure in chronic hepatitis and liver cirrhosis (author's transl)].

In 38 patients with chronic hepatitis and 53 patients with liver cirrhosis the portal vein pressure was determined by wedged hepatic vein pressure (WHVP). There were significant differences among chronic persistent, chronic active hepatitis and liver cirrhosis. The wedged hepatic vein pressure increased in chronic active hepatitis according to the rate of hepatic connective tissue. The platelet count and the thromboplastin time were correlated to the values of wedged hepatic vein pressure not only in chronic active hepatitis but in liver cirrhosis as well. The correlation among serum albumin level, bromsulphalein retention and systolic blood pressure after Riva-Rocci and wedged hepatic vein pressure was significant in liver cirrhosis exclusively. Even if the determination of wedged hepatic vein pressure does not permit an absolute statement on the risk of hemorrhage of esophageal varicosis it is nevertheless suited for follow-up controls in chronic hepatitis and liver cirrhosis and renders possible an outlook on the progress of the disease.

Blood Pressure Determination↗
PubMed1978

[Differing results of direct and indirect solid phase radioimmunoassay for HBsAg in acute hepatitis (author's transl)].

In 54 patients suffering from acute viral hepatitis the indirect solid phase radioimmunoassay (ind-SPRIA) for HBsAg was positive in 9 cases the direct solid phase radioimmunoassay (d-SPRIA) being negative. In 2 further cases ind-SPRIA was positive during several weeks but d-SPRIA only once. AntiHBc could be detected in 9 of these patients. In 7 patients the usual decrease of the transaminase activity was followed by a second elevation with prolongation of disease. The unknown factor detected by ind-SPRIA suggests a special form of acute hepatitis.

Adult↗
PubMed1978

[The different biochemical course of HBsAg-negative and HBsAg-positive hepatitis (author's transl)].

In 73 patients with HBsAg negative hepatitis and in 94 patients with HBsAg positive hepatitis (hepatitis B) laboratory findings were compared: GOT, GPT, AP, gamma-GT, bilirubin, sedimentation rate and gamma-globulins. In the beginning of the disease there was little difference. But comparing the maximal values patients with hepatitis B showed significantly higher GOT, GPT, de-Ritis, and bilirubin levels than patients with HBsAg-negative hepatitis. There was a correlation between de Ritis quotient and bilirubin. The difference of HBsAg negative and HBsAg positive hepatitis might be due to different reactions of cellular mediated immunity.

Adult↗
PubMed1976

[Significance of indirect hemagglutination test with polyvalent E. coli O antigens to diagnosis of pyelonephritis (author's transl)].

78% of 32 patients with acute E. coli pyelonephritis had significantly increased antibody titers to polyvalent E. coli antigens (PA). Only 14% of 42 patients with chronic E. coli pyelonephritis had increased antibody titers. 143 E. coli O groups were used in hemagglutination test distributed into 8 antigen pools. Antibody titers to common O groups were more elevated than those to uncommon O groups. The result showed that hemagglutination test with PA can be usefull for serologic diagnostic of acute pyelonephritis.

Acute Disease↗
PubMed1976

[The determination of hemagglutinating antibodies with polyvalent E, coli O antigens in infections of the urinary tract in childhood (author's transl)].

42 sera from children with acute urinary tract infections and 71 sera from children with chronic recurrent urinary tract infections were examined for antibodies by means of indirect hemagglutination with eight different polyvalent O antigens from a total of 143 E. coli strains and compared with a control group from 142 children. 72% of the children with acute urinary tract infection had a raised antibody titer. On the other hand, the group with chronic recurrent urinary tract infection showed raised antibody titers in only 23% of cases. The method is suitable for random sample investigations and for observation of the course of the disease.

Acute Disease↗
PubMed1976

[Electron miscoscopy studies of liver tissue in patients with amanita phalloides poisoning].

Electron microscopic findings of the liver are being described found in 4 patients aged from 12 months to 26 years after poisoning with Amanita phalloides. Marked alterations were seen in nuclei, in the endoplasmic reticulum, and in mitochondria. Morphologic criteria of cholestasis were observed in one patient. Extreme cellular edema was found in two patients. Since our findings differ considerably in several points from those patients with Amanita phalloides poisoning previously reported, one may suppose, that e.g. age, sex, preexisting damage and liver function might be highly important for the extent and form of resulting liver damage.

Adolescent↗
PubMedDate not supplied

[Sensitization to nickel sulfate in patients with ileitis terminalis (Crohn disease)].

The history of inpatients with Crohn's disease revealed several occurrences of contact dermatitis due to metal ions. Therefore, we considered the question as to whether allergic reactions to amalgam fillings or mercury, delivered in small amounts, could be a factor in the activity of regional enteritis. 23 patients with Crohn's disease (15 females, 8 males), aged from 20 to 44 years were screened by an extended standard patch test (following the rules of the ICDRG). Surprisingly, no case of hypersensitivity to amalgam and/or mercury was found. However, nickelsulfate yielded positive reactions in 39.1% of all tested patients (9/23). In comparison to the normal population this prevalence of nickelsulfate hypersensitivity is distinctly increased. It may be an epiphenomenon of Crohn's disease (sensitization via an enhanced permeability of the irritated mucous membranes for nutritive nickelsulfate) or an etiopathogenetic co-factor. In the latter case regional enteritis might be regarded as an allergic-irritative disease of the bowel.

Adolescent↗