Search PubMed⌕ Search

Biomedical subjects

W D Steck

Publications and source records attributed to W D Steck.

At least 19 recordsLinked to original sources
PubMed1996

Quinidine-induced pigmentation.

Antimalarial agents have long been known to cause a variety of pigmentary disturbances. Quinidine, a cincha alkaloid and D-isomer of quinine, is widely used for the treatment of ventricular arrhythmias. A paucity of literature, however, exists concerning quinidine-associated hyperpigmentation. We describe a case of focal ceruloderma we believe to be secondary to quinidine therapy.

Anti-Arrhythmia Agents↗
PubMed1996

Familial leiomyomata.

The autosomal dominant inheritance of multiple piloleiomyomas has been previously described. This is a report of two such cases, along with a brief review of the diagnosis, classification, and treatment of the cutaneous leiomyomas.

Diagnosis, Differential↗
PubMed1993

Pen push purpura: iatrogenic nail bed hemorrhages in the intensive care unit.

Peculiar fingernail hemorrhages appeared in a febrile, comatose patient several weeks after she was admitted to the hospital. Bedside questioning of the nursing staff uncovered a frequently used neurologic examination maneuver as the cause. We suggest the term "pen push purpura" to describe this phenomenon. The clinical significance and various causes of nail bed hemorrhages are reviewed.

Female↗
PubMed1989

Wells' syndrome.

Explore the source record for details and available documents.

Cellulitis↗
PubMed1989

Systemic mycoses.

Explore the source record for details and available documents.

Bibliographies as Topic↗
PubMed1989

Blastomycosis.

Blastomycosis is an uncommon, sometimes self-healing, sometimes fatal, infectious disease caused by the fungus Blastomyces dermatitidis. Although amphotericin B is still considered the drug of choice, ketoconazole and several other imidazole drugs--miconazole, itraconazole, econazole--have shown promise in the treatment of blastomycosis.

Amphotericin B↗
PubMed1986

Eosinophilic cellulitis associated with urticaria. A report of two cases.

Two patients with the clinical and histopathologic findings of eosinophilic cellulitis are presented. In one patient there was a definite relationship between upper respiratory tract infection and flare-ups of eosinophilic cellulitis. This patient's condition was superimposed on a long history of chronic urticaria. In the other patient a relationship to recurrent sinusitis was possible but not definite. There were no other contributory underlying skin diseases in either patient. Eosinophilic cellulitis is not likely a disease entity as such but, instead, represents a severe urticarial hypersensitivity reaction to various stimuli. Collagen alteration by eosinophil granules results in flame figure formation and a granulomatous response, which may explain the prolonged persistence of the lesions.

Adult↗
PubMed1986

Electrocardiography electrode and hand dermatitis from parachlorometaxylenol.

Parachlorometaxylenol is used as a germicide in many topical products. To our knowledge, this is the first case of dermatitis from parachlorometaxylenol in electrocardiograph electrodes used with cardiac monitors. The patient also had hand eczema from a germicidal soap containing parachlorometaxylenol. In addition, our patient had a cross-reaction to dichlorometaxylenol, a reaction not previously reported.

Aged↗
PubMed1984

Spontaneous improvement of Cronkhite-Canada syndrome in a postpartum female.

A case report of a 34-year-old female with the Cronkhite-Canada syndrome is presented. The patient developed the characteristic clinical features of intestinal polyposis, skin pigmentation, alopecia, and onychodystrophy which later resolved. An unusual feature was that symptoms developed during the postpartum period. This is the youngest female patient described with the syndrome. The etiology, pathophysiology, clinical manifestations, and management of the Cronkhite-Canada syndrome are reviewed.

Adult↗
PubMed1983

Cowden's disease (multiple hamartoma and neoplasia syndrome). A case report and review of the English literature.

Cowden's disease is a multisystem disease complex inherited as an autosomal dominant trait with incomplete penetrance and variable expressivity. Its mucocutaneous findings are the most characteristic feature of the syndrome and the key to its diagnosis. The findings of multiple facial trichilemmomas appear to be pathognomonic of the disease. Multiple extracutaneous hamartomas are a regular feature of Cowden's disease. The most important hamartomas to recognize include fibrocystic disease of the breast, thyroid goiters or adenomas, multiple polyposis of the gastrointestinal tract, and ovarian cysts. Although many developmental anomalies have been described in these patients, only adenoid facies and high-arched palates appear significant from a statistical standpoint. The most important feature of Cowden's disease, that which makes early recognition absolutely essential, is an increased prevalence of malignant neoplasia primarily in affected female patients, and principally involving the breasts and thyroid gland. All patients, however, must be screened for occult malignancies of all types. A detailed review of the English literature offers a basis for the formation of guidelines that should be helpful in making a diagnosis of the disease.

Adolescent↗