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Biomedical subjects

W D Sager

Publications and source records attributed to W D Sager.

61 records · Page 4Linked to original sources
PubMed1976

[Results of radiotherapy of bronchial carcinoma (author's transl)].

In a joint retrospective study by 17 radiotherapy clinics in German-speaking countries the results of treatment of bronchial carcinoma after radiotherapy were analysed in 7503 cases. The age peak was between the 60th and 70th year. Squamous-cell carcinoma was the most frequent histological type, followed by anaplastic carcinoma, with adenocarcinoma being rare. There was a high proportion of histologically not clearly identified cases (27% in central and 35% in peripheral carcinomas). Survival rate at one year was 31% for central (3662 patients) and peripheral (961 patients) tumours, but only 2% at five years. Prognostically there was no difference between histological types and kind of radiotherapy or technique, but total dose affected survival rate. At a total dose of less than 5000 rd the survival rate at five years was minimal. The prognosis of combined surgical and radiotherapeutic measures was slightly better than with a radiotherapy alone, but results were unpredictable for the individual case. It is concluded that radiotherapy aiming at cure should be used in imoperable bronchial carcinoma if the tumour state and general condition of the patient appear to make a cure possible. But if this is not the case, radiotherapy should be used only palliatively, i.e. only to ameliorate symptoms.

Adenocarcinoma↗
PubMed1976

[A complex malformation of the first and second branchial arch and of the first bran-hial arch and of the first branchial cleft. Dysostosis temporo-spheno-facialis (author's transl)].

A complex malformation of the first and second branchial arches and of the first branchial cleft is described; there was also involvement of the axial skeleton and the limbs. The syndrome has been described by us as dysostosis temporo-sphenofacialis and could not be classified with any previously described entity. The reason for this was due to the imcomplete description of previously published cases, but also the large number of possible combinations of changes in various organs which can occur. In order to understand the condition more clearly, the aetiology and pathogenesis of abnormalities of the face and skull have been considered in detail. Adequate and accurate radiographic examination is considered as a pre-requisite to surgery, which can be cosmetic or improve hearing, and which may have good results.

Abnormalities, Multiple↗
PubMed1976

[Results of radiotherapy of malignant testicular neoplasms].

It is very difficult to compare the therapeutic results of malignant testicular tumours because of the different histological classification systems, the uncertainty in the definition of the different stages, the error rate of the lymphography which amounts up to 35%, and the multitude of surgical, radiation, and chemotherapeutic methods. A histological classification and an exact determination of the stage is required as a condition of beginning a radiotherapy. The desirable focal dose for seminomas is between 4000 and 5000 rad, the maximum dose for teratomas is 6000 rad. For the stages T1-3N0 the iliac and the paraaortic lymph nodes are irradiated, for the stages T1-4N1-2 the interpleural space andthe supraclavicular region are included. For a group of 91 patients there was reached a five-year survival rate of 85,5% in case of seminomas and of 64% in case of teratomas.

Adult↗
PubMed1975

[The roentgen diagnosis of chronic inflammatory disease of the middle ear with tomography (author's transl)].

Tomography of the middle ear is a reliable method for the diagnosis of a cholesteatoma. Radiological diagnosis is possible in nearly all cases showing changes in the bony margins of the tympanic cavity and of the retro-tympanic spaces. Bone changes of the medial wall of the tympanic cavity, unless they extend into the labyrinth, can only be shown by tomography. In contrast to cholesteatomas, osteolytic changes are rare and only superficial as a result of ordinary, chronic otitis media. They can be demonstrated by tomography, particularly in the region of the lateral wall of the attic. Diffuse enlargement of the epitympanic recess is rare in chronic otitis media. Destruction of the ossicles may be found with cholesteatomas and, more rarely, with chronic otitis media; evidence of destruction of the ossicles is therefore not adequate for a radiological diagnosis of a cholesteatoma. In addition, the demonstration of bone changes is necessary for this diagnosis. In general, the tomographic investigation of the ossicles is subject to certain limitations. In most cases, destruction of ossicles can be inferred only if their size is reduced, their shape is altered, or if they appear to be absent. Unsharpness of normal-sized or only slightly reduced ossicles is an unreliable sign and has causes other than superficial destruction. An impression of unsharp and "washed out" contours may be due to inflammtory osteoporosis of the ossicles, or to a reduced absorption differential between porotic bone and abnormal contents of the tympanic cavity. This process may even produce the appearance of absence of the ossicles. In the presence of cholesteatomas, the unsharpness is more probably due to superficial destruction than is the case with chronic otitis without a complicating cholesteatoma.

Cholesteatoma↗
PubMed1975

[Improvement of focal dose determination in the small pelvis].

An easily applicable auxiliary method in order to register exactly the topographic relations on horizontal sections in the small pelvis is indicated. Only the body contour, pelvis pictures on two planes, diapositives with the corresponding pictures of the cross-section and a photographic enlarger are needed. A sagittal tomogram in the median plane, and for radium therapy the localization pictures on two planes are other helps.

Cervix Uteri↗
PubMedDate not supplied

Computer tomography in transient global amnesia.

16 patients with transient global amnesia (TGA) have been investigated by computer tomography. 3 had a completed stroke associated with the TGA. The findings of computer tomography were normal in 7 patients. Atrophy alone was seen in 2 patients. A single hypodense lesion was found in 6 patients; a bilateral lesion in 1 patient. All 3 patients with amnesic stroke showed a hypodense lesion in the CT.

Adult↗