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PubMed1983

A computer program using a nested analysis of variance in morphometric sampling.

The quality of the sample set is absolutely essential in a morphometric analysis. In this paper a computer program is described which uses a nested analysis of variance in defining the sample. The program denotes those levels of the sampling protocol at which additional sampling should be performed to reduce the variance within the sample set. Furthermore, the program is written for use on a microcomputer which allows it to be used routinely in monitoring a sample set.

Analysis of Variance↗

PubMed1982

Cellular distribution within the rat adenohypophysis: a morphometric study.

A morphometric analysis of the cell types within the adenohypophysis of the female rat was conducted with an emphasis on regional variations. Type I and type II gonadotropes and corticotropes had the largest volumes, mammotropes and somatotropes were of medium size, and thyrotropes and chromophobes were the smallest cells. There was no regional variation in the volumes of the respective cell types. Somatotropes and mammotropes were most numerous, followed by the gonadotropes, chromophobes, corticotropes, and thyrotropes. There was no significant regional localization of the somatotropes, mammotropes, corticotropes, and thyrotropes. Gonadotropes were best defined as two populations with type I cells being localized in the central regions and type II cells being distributed throughout the gland. Chromophobes were the only cells with a significant distribution in the anterior regions and were most numerous in the anterior peripheral regions. These fine-structural morphometric findings are discussed in relation to other studies of the adenohypophysis that utilize immunocytochemistry.

Animals↗