Kinetic heart pumping.
Explore the source record for details and available documents.
Biomedical subjects
Publications and source records attributed to W D Kelly.
Explore the source record for details and available documents.
A 13-year-old female with biochemically proven alpha mannosidase deficiency (mannosidosis) developed a bilateral destructive synovitis of the ankle region, a hitherto unreported complication of this disease. Clinically, it was believed to be a pigmented villonodular synovitis. Histologically, the synovium was thrown into villous folds and was infiltrated with clear histiocytes having rare collections of PAS-positive, diastase-resistant material. Electron microscopy demonstrated numerous membrane bound vacuoles filled with granular, amorphous material. This lesion can be distinguished from pigmented villonodular synovitis by its bilaterally symmetrical distribution, the monomorphic population of cells, and the presence of material having the histochemical and ultrastructural properties of (neutral) oligosaccharides.
Radical resection after unsuccessful radiotherapy for post cricoid carcinoma may provide longterm cures even in patients who have cervical node involvement. The best palliation is achieved by visceral replacement of the pharynx but this carries a significant mortality rate. In patients with tumors considered too extensive for radiotherapy, successful short term palliation can be achieved with pharyngolaryngectomy and left colon replacement.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.