Search PubMed⌕ Search

Biomedical subjects

W D Jones

Publications and source records attributed to W D Jones.

At least 55 records · Page 3Linked to original sources

Applications of reconstructive craniofacial techniques to acute craniofacial trauma.

Increasing familiarity with elective reconstructive approaches to craniofacial deformity has led to the application of a similar multispecialty approach to repair of selected cases of massive frontal and upper facial trauma. The fundamental steps in craniofacial reconstruction are outlined. The process of patient selection is emphasized. Illustrative case histories review the management of this type of injury. Contributions from anesthesiology, neurosurgery, ophthalmology, and plastic surgery are required. Specialized facilities for postoperative care are mandatory.

Adult↗

Host modification and restriction with a mycobacteriophage isolated from a pseudolysogenic Mycobacterium chelonei.

A pseudolysogenic Mycobacterium chelonei and its phage phi630 are described. Phage phi630 is the first mycobacteriophate reported to be resistant to the nonpolar solvents chloroform, dioxan and diethyl ether. The phage had a latent period of 75 min, a rise period of 90 min and a burst size of 5I. Evidence is presented for host modification and restriction. Phage phi630A, grown on host strain M. chelonei F-630 Rg, plated on the alternative host M. smegmatis ATCC607 with an efficiency of plating (e.o.p.) of 10(-5). Phage phi630B, grown on host M. smegmatis, plated with an e.o.p. of 10(-5) on the alternative host F-630 Rg. Phages phi630A and phi630B absorbed equally well on their alternative hosts and on their indicator host strains. The progeny of plaques from initial platings on the alternative host, when grown in the alternative host, exhibited a marked reduction in e.o.p. on their original host.

Bacteriophage Typing↗

Use of phage F-phi WJ-1 of Mycobacterium fortuitum to discern more phage types of Mycobacterium tuberculosis.

A total of 125 strains of Mycobacterium tuberculosis from the Southeastern area of the United States was subjected to phage typing. In addition to the five major mycobacteriophages, a new phage, F-phi WJ-1, was used in the study. The results obtained with the five major phages were: type A0, 35.2%; TYPE B, 29.6%, and type C, 4.0%. The remaining 21.2% of the strains phaged typed as subgroups A1 through A6. These percentages were similar to the typing results of earlier studies. The new phage, F-phi WJ-1, subdivided each of the phage types, with the exception of type C, into two subgroups. The possible role of host modification-restriction of the phages used in phage typing of strains of M. tuberculosis is discussed.

Bacteriophage Typing↗