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Biomedical subjects

W D Johnson

Publications and source records attributed to W D Johnson.

299 records · Page 17Linked to original sources
PubMedDate not supplied

Modified mid-sternotomy approach for exposure of left internal mammary artery and the circumflex artery territory.

Despite coronary artery bypass grafting being a common operation today, obtaining an optimal exposure of the left internal mammary artery for its easy harvest can be difficult at times. Similarly, it may not always be easy to obtain adequate access to the left posterolateral surface of the heart (for the circumflex-marginal artery system). We describe a simple modification of the standard mid-sternotomy incision that helps to overcome both of these problems without using any cumbersome assembly of retractors and with minimal side effects.

Coronary Artery Bypass↗
PubMedDate not supplied

The influence of CD4+ T cells, HIV disease stage and zidovudine on HIV isolation in Bahia, Brazil.

HIV-1 isolation was attempted on 72 individuals, including persons with known HIV infection and five without proven HIV infection but with indeterminate Western blot patterns, as well as on low-risk HIV seronegative persons. The ability to detect HIV-1 from culture supernatant by p24 antigen capture assay was evaluated by segregating patients by absolute CD4+ cell counts, clinical stage of disease, p24 antigenemia and zidovudine use. The likelihood of a p24 positive HIV culture was highest among patients with CD4+ T-cell counts below 200/ul and patients with advanced clinical disease. Use of zidovudine did not affect the rate of HIV positivity in cultures.

Antiviral Agents↗
PubMedDate not supplied

Comparison of driving gases for IABPs.

Several aspects of CO2 vs He as the driving gas in intra-aortic balloon counterpulsation systems were reviewed and investigated. Carbon dioxide seems to be significantly safer than other gases, but not benign. Helium produces a faster balloon response, but the physiologic significance has not been defined. Balloon driving gases become diluted in relatively short time. Leak detection systems have significant limitations. It seems prudent for users of dual-balloon systems to periodically measure the PCO2 of the driving gas. A better method of purging the single-balloon system was developed.

Animals↗