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Biomedical subjects

W D Hiltmann

Publications and source records attributed to W D Hiltmann.

At least 19 recordsLinked to original sources
PubMed1999

Congenital nasal hemangiopericytoma: intrauterine, intraoperative, and histologic findings.

Hemangiopericytoma is a rare tumor of mesenchymal origin. To date, 91 cases of nasal or paranasal hemangiopericytoma and 59 congenital hemangiopericytomas have been reported in the literature. A congenital hemangiopericytoma arising from the nasal cavity and skull base has not yet been described. We report a case of a male newborn with a highly vascular nasal tumor diagnosed by in utero sonography with three-dimensional surface reconstruction. The tumor extended to the right anterior skull base, the right nasal cavity, and the right side of the nasal pyramid. A complete resection by neodymium:yttrium-aluminum-garnet-potassium titanyl phosphate ("Nd:YAG-KTP") laser was performed on the day of cesarean section at 33 weeks' gestation. The tumor was diagnosed as hemangiopericytoma by histologic and immunohistochemical findings. Postoperative nasal flow, feeding, and sight were unimpaired. At the 9-month follow-up, the infant remained free of disease.

Female↗
PubMed1997

Pelvic ultrasound scanning of the ovaries in adolescent anorectic patients at low weight and after weight recovery.

In sixteen adolescent anorectic inpatients with secondary amenorrhea pelvic ultrasound examination of the ovaries was performed at lowest weight and after weight recovery. The outcome was assessed six months later at follow-up, assigning the patients to the categories of good, intermediate and poor outcome according to the modified Morgan and Russell criteria. At lowest weight all patients' ovaries were smaller than expected for age. After weight recovery the good outcome group had mature and fully developed ovaries whereas the ovarian morphology of patients with poor outcome remained prepubertal. The ovarian volume in the good outcome group was significantly higher than in the poor outcome group. From a threshold BMI of 17.8 upwards we observed a positive linear correlation between BMI and ovarian volume. At BMI 18 the probability for recovered ovaries was 53% rising to 82% at BMI 19.8, which was the highest noting in our study. Nevertheless, we could not find a clear cut-off BMI for definite prediction of recovered ovaries. Therefore, in patients with anorexia nervosa pelvic ultrasound is a very suitable method for determining the target weight required for recovery of ovarian function and resumption of menses. Normalized ovaries indicate favourable outcome and physical recovery.

Adolescent↗
PubMed1978

[The effects and side-effects of the intra-cervical application of prostaglandin F-2 alpha during early pregnancy (author's transl)].

In order to avoid the traumatic dilatation of the cervix for therapeutic abortions 200 micrograms of prostaglandin F-2 alpha were injected into the cervix. The effect on dilatation of the cervix was compared with the injection of normal saline in the control group. Without side effects the injection of prostaglandin F-2 alpha resulted in dilatation of the cervix and softening of the cervix. Normal saline had no effect. At present it is unknown whether the dilatory effect of prostaglandin F-2 alpha on the cervix is local or secondary to uterine contractions.

Abortion, Legal↗
PubMed1976

[Potassium substitutes during tocolysis].

The level of serum potassium during tokolytic therapy with Partusisten and Isoptin decreases in the first 24 hours of therapy. This decrease is not due to an increase in renal potassium elimination. During tokolytic treatment the serum level of potassium returns to its normal value after 48 hours without potassium substitution. While there is a decrease in serum potassium noticeable changes in electrocardiogram which are typial for hypopotassemia are observed. These changes disappear afer 48 hours of tokolytic treatment but never the less the initial serum potassium drop should be balanced by potassium substitution within these 48 hours.

Adrenergic beta-Agonists↗
PubMed1976

[Behaviour of serum concentrations of glucose, immunoreactive insulin and potassium ions in newborns after long term or crash treatments with Partusisten or Partusisten in combination with Isoptin (author's transl)].

The investigation was done on 50 infants born of metabolic healthy mothers. A group of 10 women received short term treatment with Partusisten and Isoptin. Another 10 were treated over the same period with Partusisten only. A further group of 15 received long term treatment (more than 7 days) with Partusisten and Isoptin and a final group of 15 mothers received placebos. Serum concentrations of glucose, immunoreactive insulin and potassium, together with acid-base-status and other important blood chemistry were determined in mothers and newborns directly postpartum. Blood sugar, immunoreactive insulin and potassium were further determined in the newborns 30 minutes, 60 minutes, 2 hours and 6 hours after birth. The results showed that a temporary relative hypoglycaemia occured in the newborns in short term as well as long term treatment with Partusisten or Partusisten in combination with Isoptin. Temporary derangements in insulin-glucose equilibrium were also seen in newborns from mothers receiving long term treatment. It was also demonstrated that approximately 1 hour post-partum, blood sugar and immunoreactive insulin of the newborn attained values compatible with normal carbohydrate metabolism. From these results it is indicated that infants born of mothers, who received tocolytic treatments with Partusisten or Partusisten in combination with Isoptin, should be given sodiumbicarbonate and glucose directly after birth.

Acid-Base Imbalance↗
PubMed1976

[Changes in maternal cardiovascular parameter during tocolysis and in the dorsal position shock syndrome (author's transl)].

Maternal circulatory parameters and fetal heart rate were measured in 25 healthy pregnant women in the last trimenon during treatment with Fenoterol, Fenoterol in combination with Verapamil and Verapamil alone. Dosages were used in accordance with the tocolytic guidelines from Weidinger and Wiest. We were able to demonstrate that the betamimetic Fenoterol alone and in combination with the Ca++-antagonist Verapamil strongly increases the maternal heart rate an the maternal cardiac output whereas the peripheral resistance decreases accordingly. The average blood pressure stayed leveled, so that a decreased uterine blood flow cannot be assumed under betamimetics from the maternal cardiovascular point of view. However, there are indications for an increased placental blood flow during tocolysis. The betamimetic drug show no significant effect on the fetal heart rate. Additional application of the Ca++-antagonist Verapamil during tocolysis with Fenoterol (in dosages usually used for tocolysis) doesn't change cardiovascular reactions caused by Fenoterol. Change in position from supine to left lateral position caused a short term increase in the maternal cardiac output even noted in pregnant women without a clinically observed cavasyndrom. These changes of maternal cardiac output are comparable with those in orthostatic stress situations.

Adult↗
PubMedDate not supplied

[The variability of the QRS loop in the orthogonal lead system of frank and schmitt (SVEC III) (author's transl)].

A method has been previously described, to test the accuracy of lead fields. This method is used here to compare in 7 persons the relative validity of the two orthogonal lead systems of Frank and Schmitt (SVECC III). The variables the variation of which characterizes the validity of the systems, are the spatial position (represented by the spatial angles of the normal of the broadside view) and the variations in shape of the vector loops. The latter are measured by a comparison of the length of vectors in a distance of 5 degrees, starting with the maximal vector and proceeding from here to both sides. The vectors of loops in two different heart positions are compared by means of their correlation coefficients, and one of the loops is rotated in space as long as this correlation coefficient reaches a maximum. The data are handled by a computer. The optimal correlation coefficients, the regression coefficients and the differences in the spatial angles of the planes, in which the loops show their broadside view, are compared. The Frank system has a significantly lower variability of these values, by extreme dislocations of the heart, either by respiratory or by positional dislocations.

Adult↗