Accidental methylene chloride fatality.
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Accidents↗
Biomedical subjects
W D Collom
Publications and source records attributed to W D Collom.
Fatal strychnine ingestion.
A postmortem case involving ingestion of a strychnine-containing preparation is reported. Strychnine levels were determined in blood, urine, bile, liver, kidney, stomach contents, small and large intestines, and brain. The procedure, which is sensitive and specific, employs a gas-liquid chromatograph equipped with a flame ionization detector (FID). The extraction procedure using 5 mL of body fluids or tissue homogenate is described in detail. This is the first strychnine mortality in Allegheny County within a period of 20 years.
Chromatography, Gas↗
Blood versus synovial fluid ethanol concentrations in humans.
Many tissues have been analyzed for their relevance in prediction of blood ethanol concentrations, with varying results. Synovial fluid is contained and protected by the bursa sac. Because of its high water content, it may be a suitable biological fluid for analysis if a linear correlation could be established between blood and synovial fluid ethanol concentrations. Blood-synovial fluid ratios of ethanol in 28 human cadavers, using an internal standard, exhibit a good distribution ratio with an average of 0.99 +/- 0.29 and a correlation coefficient of 0.89. This study shows that synovial fluid is a good alternative biological sample for prediction of blood ethanol levels within a range.
Ethanol↗