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Biomedical subjects

W C Yip

Publications and source records attributed to W C Yip.

At least 127 records · Page 7Linked to original sources
PubMed1983

Seasonal variations in admissions to a tropical paediatric unit.

The monthly admissions over the last 10 years (1972-1981) of children with common illnesses to the Department of Paediatrics, National University of Singapore, were analyzed to ascertain if there were any significant seasonal patterns. The method used (developed by Walter and Elwood) consists of estimating the amplitude of seasonal variations and the time at which the maximum occurs in a postulated simple harmonic fluctuation. Six out of the 9 diagnostic groups studied were found to have significant seasonal variations in at least 5 out of 10 years or 3 out of the last 5 years: pharyngitis, bronchitis, broncho-pneumonia, bronchial asthma, gastro-enteritis, and febrile convulsions. Febrile convulsions showed the best correlation (in terms of the number of monthly admissions) with the other illnesses showing seasonal fluctuations. Admissions for bronchial asthma were negatively correlated with the others. No consistent pattern in the time of peak number of admissions was discernable. The seasonal variations demonstrated are probably related to outbreaks of viral infections which tend to occur round the year in the tropics.

Asthma↗
PubMed1983

The incidence of atopy in steroid-responsive nephrotic syndrome: clinical and immunological parameters.

Fifty-nine children with steroid-responsive nephrotic syndrome (SRNS), ages ranging from two to 18 years, were studied to determine the incidence of atopy, using both clinical and immunological parameters. Children with SRNS were found to have a significantly higher incidence of atopy both in themselves (z = 2.51, p less than 0.05) and their first-degree relatives (z = 2.34, p less than 0.05). The proportion of children with raised serum IgE levels (60%) and the geometric mean (631 U/ml) in SRNS children were significantly higher than control values, 14.5% and 136 U/ml, respectively (p less than 0.0001). Intra-group comparison showed that children with multiple relapses (more than two relapses) had higher incidence of skin test positivity to house dust mite (p less than 0.01) and to two or more antigens (p less than 0.05). Our data would suggest that atopy may be a predisposing factor in local children with SRNS.

Adolescent↗
PubMed1983

Automated blood pressure reading--its claims and its reliability.

Advances in technology have made available automated devices for rapid and easy measurements of arterial blood pressure. This study evaluates the performance of one such device, the Hitachi Digital Blood Pressure and Pulse Monitor, Model HME-20, against a standard mercury sphygmomanometer, the Accoson . Fifty four sets of systolic and diastolic readings were simultaneously obtained using the two instruments. The readings obtained by both methods correlated significantly with each other (p less than 0.001). However, the mean diastolic pressure obtained by HME-20 is significantly lower than that obtained by the Accoson (p less than 0.05). There is also a consistent underestimation of systolic and diastolic pressures of 8 mm Hg by HME-20. Moreover, linear correlation studies between HME-20 and Accoson readings reveal that the 95% confidence limits are fairly wide, which limit, therefore, the value of a single reading by HME-20. Our preliminary evaluation suggests that HME-20 is more suited to monitor the trend of blood pressure changes rather than to provide precise determination of arterial blood pressures.

Adult↗
PubMed1982

New prognostic criteria for children with cyanotic congenital heart disease.

Available oxygen and oxygen unloading capacity were determined at the time of cardiac catheterisation, from blood gas analysis, p 50 in vivo, and haemoglobin, in 79 children with cyanotic congenital heart disease, their age ranging from 2 weeks to 14 years. The patients were followed up for six months to find out how many of those without surgical intervention survived. Actuarial analysis showed that the six month survival rate among the patients with low available oxygen or oxygen unloading capacity was significantly lower (24% and 49%, respectively) compared with those with normal indices (90% and 96%, respectively). Both available oxygen and oxygen unloading capacity were superior to arterial oxygen saturation and arterial oxygen content as prognostic criteria. Haemoglobin and haematocrit were of little value in prognosis. Available oxygen appeared to be the best prognostic criterion for survival at six months. It is concluded that available oxygen and oxygen unloading capacity are useful prognostic criteria in children with cyanotic congenital heart disease. These new criteria, when used in conjunction with the conventional methods of assessing the cardiac lesion, may be of considerable help to the physician in evaluating the prognosis of the patient.

Adolescent↗
PubMed1982

Parental age and birth order in Chinese children with congenital heart disease.

Parental age and birth order were studied in 100 Chinese children with congenital heart disease (proven by cardiac catheterisation) and in 100 controls. A higher incidence of congenital heart disease was present in the children with higher birth orders. No relationship was found between the incidence and the paternal or maternal ages. Using the method of multiple regression analysis this birth order effect was significant (p less than 0.01) and independent of parental age. This finding provides indirect evidence of environmental influence in the causation of congenital heart disease, which is known to be inherited in a multifactorial manner. Family planning to limit the size of the family may possibly contribute to the reduction of the incidence of congenital heart disease.

Adult↗