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Biomedical subjects

W C Yip

Publications and source records attributed to W C Yip.

At least 91 records · Page 5Linked to original sources
PubMed1985

Transcutaneous estimation of oxygen tension in unusual clinical situations.

Transcutaneous oxygen monitoring has been used successfully in the assessment of trend in tissue oxygenation in neonates and children. This study highlights the application of transcutaneous oxygen monitoring in three unusual clinical situations: dual channel oxygen monitoring in persistent foetal circulation, hyperoxia test in the differentiation of cardiac or pulmonary central cyanosis and the effect of endotracheal intubation on tissue oxygenation. Its usefulness and potential application in these situations are discussed.

Cyanosis↗
PubMed1984

Value and limitations of bilirubin binding capacity in predicting the development of kernicterus.

The serum bilirubin (SBR) and the bilirubin binding capacity (BBC) were determined on hospital admission in 181 consecutive neonates with neonatal jaundice. Twenty-three babies were less than 2500 g and two were of birth weight less than 2000 g. Fifteen babies were preterm. There were eight cases of kernicterus. Although the serum bilirubin was generally higher in infants with a BBC less than 34 mumol/l, there was no correlation between the bilirubin binding capacity and the presence of kernicterus (r = 0.28, P greater than 0.05). However, when both the serum bilirubin and the bilirubin binding capacity were used, a low value of BBC less than 34 mumol/l increased the risk of kernicterus. Higher values of BBC, on the other hand, did not mean that there was less risk of kernicterus, other factors being equal. This, while the bilirubin binding capacity may provide an additional source of information, its limitations should always be borne in mind.

Bilirubin↗
PubMed1984

Intestinal lymphangiectasia--a report in two Chinese children.

Two Chinese infants with asymmetrical lymphoedema and steatorrhoea were investigated. The laboratory investigations showed that they had hypoproteinaemia without proteinuria. One of them showed peripheral lymphopenia and hypogammaglobulinaemia. Radiologically, they had evidence of extensive lymphangiectasia of the small intestine. This was confirmed histologically. Endoscopy of one of them showed diffuse milky nodular duodenal mucosa. The appearance of the mucosa was rather typical of intestinal lymphangiectasia.

Endoscopy↗
PubMed1984

The estimation of inbreeding from isonymy: relationship to the average inbreeding coefficient.

The inbreeding coefficient estimated by the isonymy method is often much larger than the average inbreeding coefficient (FD). One reason commonly stated is that the surnames are polyphyletic in origin in such cases. The purpose of this paper is to examine the relationship between the inbreeding calculated from isonymy and the average inbreeding coefficient. It was found that when the level of inbreeding is low, especially when the random isonymy (Pr) is much larger than FD, or when the number of surnames is small (which results in a larger value of Pr), isonymy tends to grossly overestimate FD. A small number of surnames per se (not necessarily due to polyphyletic origin of surnames) will be likely to result in an unduly high estimate of inbreeding. The equations established are illustrated by numerical examples.

Consanguinity↗
PubMed1984

Mathematical function for maternal age in Down's syndrome.

The purpose of this study is to fit a mathematic function to the observed risk figures for Down's syndrome at various maternal ages. Data from the New York State and Swedish studies were used. It was found that the estimated risks fitted the exponential relationship very well, with a correlation coefficient of over 0.94. An even better correlation was found (over 0.97) for each 5-yr period in the New York State study. The exponential relationship was given by: I = aebx, where 1/I is the estimated risk; x, the maternal age in years; and a and b, the constants. In both studies there was considerable variation in the values of a and b with maternal age as well as an excellent correlation between ln a and b for the 5-yr periods. This function may be used to test various hypotheses for the effect of maternal age in Down's syndrome.

Adult↗