Preliminary studies on the immunogenicity and amount of Escherichia coli polypeptides in biosynthetic human insulin produced by recombinant DNA technology.
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Biomedical subjects
Publications and source records attributed to W C Smith.
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Over a period of two years 180 pork pigs, 144 baconers and 144 sows from two slaughterhouses in northern England were examined for gastrointestinal parasites. Sows showed the highest level and intensity of infection, 85 per cent harbouring the dominant parasites Oesophagostomum dentatum and O quadrispinulatum; the highest worm burden recorded was 21,000. Hyostrongylus rubidus was present in 28.5 per cent of sows but virtually absent from younger pigs. Small numbers of Ascaris suum and Trichuris suis were recorded, 16 per cent and 23 per cent respectively in pork pigs and lower in older animals. Levels of parasitism appeared to be influenced by a number of management practices, in particular the housing system.
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The incidence of death from tetanus in leprosy patients has been compared with the general population. It appears that tetanus occurs less often among leprosy patients. The pathogenesis and the consequences of this are discussed.
All patients admitted to an ulcer ward in a leprosy hospital over the period of one year were screened for glycosuria. Out of 154 patients screened 4 showed glycosuria. These 4 patients had more severely complicated ulcers evidenced by their longer duration of admission. Early diagnosis and treatment of diabetes in leprosy patients with complicated ulcers is important.
Chlordiazepoxide, which blocks serotonin turnover, increased food intake; and fluoxetine, a serotonin agonist, decreased food intake. Administration of combinations of the two drugs showed an antagonistic dose-dependent relationship, implicating a satiety of hunger mechanims which is mediated by serotonin.
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