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Biomedical subjects

W C Shellhart

Publications and source records attributed to W C Shellhart.

22 records · Page 2Linked to original sources

Oral findings in fragile X syndrome.

This study compares the oral findings in fragile X syndrome individuals to those of normal age-matched patients. Sixteen fra(X) males (mean age 22 10/12 years) had a low caries rate (decayed, missing and filled surfaces (DMFS) = 12.3) and minimal intraoral hard or soft tissue disease. Rate of malocclusion, as determined by the first permanent molar classification of Angle, was not significantly different from that of matched subjects. Fra(X) subjects had a significantly higher occurrence of malocclusion as compared to matched subjects using crossbite and openbite as criteria. Palatal dimensions of fra(X) subjects did not differ significantly from those of the matched sample. The fra(X) males also demonstrated significantly more severe occlusal wear of their teeth than the matched sample.

Adolescent↗

Efficacy and safety of intravenous ketamine for the severely handicapped.

The severely and profoundly mentally and physically handicapped dental patient predominates in the institutional setting today. Many patients still require restorative dentistry, periodontal treatment, and an occasional tooth extraction. In terms of enabling treatment to be performed by the institutional dentist, intravenous agent can be effective but can be accompanied by substantial risks in this population. The anesthetic ketamine was evaluated as a sedative agent for dental treatment in this study.

Adolescent↗

General anesthesia and fragile X syndrome: report of a case.

A case report of an 11-year-old Caucasian boy with the fragile X syndrome is presented. The fragile X syndrome is a form of X-linked mental retardation with a connective tissue component that involves mitral valve prolapse. Antibiotic prophylaxis, electrocardiographic abnormalities, and special anesthetic management considerations are elements of treating patients with fragile X syndrome. The patient received morphine sulfate and scopolamine as a preoperative premedication. Ketamine was also administered intramuscularly prior to induction to gaseous anesthetic. Pancuronium was used to facilitate nasotracheal intubation. A wandering atrial pacemaker and progressive hypocapnia, both of which were managed without complication, were the only problems encountered in the anesthetic procedure.

Anesthesia, Dental↗