Biomedical subjects

W C Scott

Publications and source records attributed to W C Scott.

At least 37 records · Page 2Linked to original sources

PubMed1979

Hemodynamic effects of various modes of cardiac pacing after operation for idiopathic hypertrophic subaortic stenosis.

The hemodynamic effects of varying heart rate and pacing site were studied in 6 patients with idiopathic hypertrophic subaortic stenosis following operative relief of outflow obstruction. Ventricular pacing (117 beats per minute) resulted in a 26% decrease in cardiac output (p less than 0.02), a 54% increase in pulmonary capillary wedge pressure (p less than 0.03), and a 23% decrease in mean blood pressure (p less than 0.05), compared with normal sinus rhythm (88 beats per minute). Slow atrial pacing (112 beats per minute) did not significantly alter any hemodynamic variable compared with normal sinus rhythm. Rapid atrial pacing (143 beats per minute) produced a similar degree of hemodynamic impairment as ventricular pacing. This study demonstrates that ventricular pacing at heart rates commonly used clinically and rapid atrial rates result in a significant fall in cardiac output. Preservation of atrial systole at heart rates that allow adequate diastolic ventricular filling of a hypertrophied, noncompliant ventricle is stressed. In addition, atrial electrodes are useful to record atrial electrograms or induce rapid atrial stimulation to treat supraventricular tachyarrhythmias.

Adult↗

PubMed1978

Pelvic abscess in association with intrauterine contraceptive device.

Serious pelvic infection associated with the use of IUDs is of increasing concern to obstetricians and gynecologists. This review of the literature is accompanied by analysis of 5 years' experience at the Arizona Health Sciences Center. Of 169 patients with acute infections, 34% had an IUD in place at the onset of infection. In addition, 24 of the patients were less than 20 years of age and 35% were nulliparous. Of the nulliparous patients, 11 were rendered sterile following surgical extirpative therapy. Sixty-six patients developed pelvic and tubo-ovarian abscesses; 38% of those were related to IUD usage. Six of the pelvic abscesses and eight of the unilateral tubo-ovarian abscesses came to pelvic cleanout. Evidence presented documents the serious infection potential that IUD usage entails, the antibiotic and surgical management, the infertility that results, and the mechanism assumed responsible. In addition, the high-risk patient has been identified (young, nulliparous, sexually active, and, especially, of the lower socioeconomic strata).

Abscess↗

PubMed1978

Limits of myocardial protection with potassium cardioplegia.

Preservation of left ventricular function with various potassium-based cardioplegic solutions has been considered to be effective for at least 60 minutes during occlusion of the ascending aorta. The purpose of this study was to define the limits of protection offered by potassium alone. A single bolus of 150 ml of potassium (24 mEq per liter) in normal saline solution at 30 degrees C was injected in the aortic roots of foxhounds at the initiation of periods of 45 minutes, 60 minutes, and 75 minutes of aortic occlusion at a core temperature of 30 degrees C. Data derived from postischemic recovery phase ventricular function curves and force-velocity relations demonstrated excellent protection during 45 minutes of ischemia, inconsistent protection at 60 minutes, and poor protection at 75 minutes.

Animals↗

PubMed1978