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Biomedical subjects

W C Mann

Publications and source records attributed to W C Mann.

4 recordsLinked to original sources
PubMed1979

Determination of buflomedil hydrochloride [2',4',6'-trimethoxy-4-(pyrrolidinyl)butyrophenone hydrochloride] by reversed-phase ion-pair high-performance liquid chromatography.

A simple and rapid method for the determination of buflomedil hydrochloride [2',4',6'-trimethoxy-4-(pyrrolidinyl)butyrophenone hydrochloride] in pharmaceutical formulations by reversed-phase ion-pair high-performance liquid chromatography is described. The sample is dissolved in methanol and 1,3,5-trimethoxybenzene is added as an internal standard. The resulting solution is chromatographed on an octadecylsilane column using ion-pair partition chromatography with lauryl sulphate as the counter ion. A 25-microliter injection (containing 3.5 micrograms of buflomedil hydrochloride) produces a 60% full-scale peak (0.2 a.u.f.s.) at the absorbance maximum (275 nm). The relative standard deviation of the method ranges from 1 to 3%, depending on the particular tablet formulation examined. Excipients present in the preparations do not interfere.

Butyrophenones↗
PubMed1975

Feeding program for the institutionalized mentally retarded.

A program using techniques from behavior modification and motivation theories was initiated to improve dining room behavior in a large residential center for the mentally retarded. The program was graduated into three levels to deal with behaviors ranging from normal eating habits to total lack of self-feeding skills. The effectiveness of this program, indicated by behavioral ratings taken both before the program began and eight weeks after the program was in operation, was shown in significantly improved eating habits.

Behavior Therapy↗
PubMedDate not supplied

A quarterway house for adult psychiatric patients.

An intermediate step between living on a hospital ward and living in the community was considered necessary for many acute and chronic patients preparing to leave Harlem Valley Psychiatric Center in New York. A quarterway house program was initiated to help patients acquire the skills and coping mechanisms they could not easily acquire on a ward setting, but which they would need to meet the demands of living in the community. The quarterway house program described may offer ideas to others who are attempting to help patients prepare for living outside a state hospital.

Adult↗